Cellular Functions of the Plasma Membrane Estrogen Receptor

Postmenopausal Estrogen Therapy and Cardiovascular Disease

1991 • 2,008 citations

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1996 • 1,473 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.

1996 • 992 citations

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells.

1996 • 964 citations

Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

1999 • 895 citations

Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells

1977 • 686 citations

Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription.

1994 • 667 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

17-β Estradiol Protects Neurons from Oxidative Stress-Induced Cell Death in Vitro

1995 • 612 citations

HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells.

1995 • 599 citations

The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons

1999 • 581 citations

Activation of ternary complex factor Elk-1 by MAP kinases.

1993 • 561 citations

Membrane estrogen receptors identified by multiple antibody labeling and impeded‐ligand binding

1995 • 532 citations

Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat

1997 • 512 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 478 citations

Estrogen Increases Endothelial Nitric Oxide by a Receptor Mediated System

1995 • 403 citations

Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation.

1991 • 378 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ER and ER Expressed in Chinese Hamster Ovary Cells

1999 • 371 citations

Estrogen Relaxes Coronary Arteries by Opening BK _Ca Channels Through a cGMP-Dependent Mechanism

1995 • 345 citations

Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia.

1994 • 310 citations

Cell surface-binding sites for progesterone mediate calcium uptake in human sperm.

1991 • 291 citations

Role of Estrogen Replacement Therapy in Memory Enhancement and the Prevention of Neuronal Loss Associated With Alzheimer’s Disease

1997 • 280 citations

Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption.

1997 • 269 citations

Nongenomic effects of 17 beta-estradiol on maturing human oocytes: relationship to oocyte developmental potential.

1995 • 235 citations

Estrogen Replacement Therapy In Older Women: A Neuropsychological And Brain MRI Study

1996 • 205 citations

Glucocorticoid Receptor-Like Antigen in Lymphoma Cell Membranes: Correlation to Cell Lysis

1987 • 177 citations

Phospholipase C β and Membrane Action of Calcitriol and Estradiol

1997 • 177 citations

Cell signaling and estrogens in female rat osteoblasts: A possible involvement of unconventional nonnuclear receptors

1993 • 175 citations

Estrogen and Progesterone Inhibit Vascular Smooth Muscle Proliferation*

1997 • 171 citations

Partial purification and characterization of oestrogen receptors in subfractions of hepatocyte plasma membranes

1980 • 160 citations

17β-Estradiol inhibits the voltage-dependent L-type Ca2+ currents in aortic smooth muscle cells

1995 • 145 citations

Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription

1997 • 143 citations

Oestrogen and progesterone inhibit the stimulated production of endothelin-1

1998 • 126 citations

Effects of Estrogen on Nonverbal Processing Speed and Motor Function in Girls with Turner’s Syndrome¹

1998 • 124 citations

Steroid hormones modulate the production of nitric oxide and cGMP in the rat uterus.

1994 • 120 citations

Estradiol Coupling to Endothelial Nitric Oxide Stimulates Gonadotropin-Releasing Hormone Release from Rat Median Eminence Via a Membrane Receptor*

1999 • 115 citations

A Novel, Synergistic Interaction Between 17 β-Estradiol and Glutathione in the Protection of Neurons against β-Amyloid 25–35-Induced Toxicity In Vitro

1998 • 104 citations

Nongenomic effects of 17 beta-estradiol on maturing human oocytes: relationship to oocyte developmental potential

1995 • 97 citations

Estradiol Activates the Prostate Androgen Receptor and Prostate-specific Antigen Secretion through the Intermediacy of Sex Hormone-binding Globulin

1997 • 93 citations

Effects of 17β-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the rats

1997 • 90 citations

Effects of Estrogen on Nonverbal Processing Speed and Motor Function in Girls with Turner's Syndrome

1998 • 83 citations

Estradiol increases cyclic adenosine monophosphate in rat pulmonary vascular smooth muscle cells by a nongenomic mechanism.

1996 • 80 citations

Estrogen and Progesterone Inhibit Vascular Smooth Muscle Proliferation

1997 • 69 citations

Membrane binding sites and non-genomic effects of estrogen in cultured human preosteoclastic cells

1996 • 64 citations

17β-Estradiol regulation of protein kinase C activity in chondrocytes is sex-dependent and involves nongenomic mechanisms

1998 • 61 citations

Effect of 17β-estradiol on chondrocyte membrane fluidity and phospholipid metabolism is membrane-specific, sex-specific, and cell maturation-dependent

1996 • 52 citations

Steroid hormones modulate the production of nitric oxide and cGMP in the rat uterus

1994 • 51 citations

Nongenomic aldosterone effects: The cell membrane as a specific target of mineralocorticoid action

1995 • 49 citations

Estrogen blocks parathyroid hormone (PTH)-stimulated osteoclast-like cell formation by selectively affecting PTH-responsive cyclic adenosine monophosphate pathway.

1996 • 44 citations

Estradiol Coupling to Endothelial Nitric Oxide Stimulates Gonadotropin-Releasing Hormone Release from Rat Median Eminence Via a Membrane Receptor

1999 • 34 citations

Hypoglycemia-induced seizures reduce cyclic AMP response element binding protein levels in the rat hippocampus

1998 • 21 citations

Estrogen blocks parathyroid hormone (PTH)-stimulated osteoclast-like cell formation by selectively affecting PTH-responsive cyclic adenosine monophosphate pathway

1996 • 20 citations

Deleted Work

1955 • 0 citations