Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1977 • 2,105 citations

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1995 • 2,075 citations

Postmenopausal Estrogen Therapy and Cardiovascular Disease

1991 • 2,008 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women

1994 • 708 citations

Estrogen modulates responses of atherosclerotic coronary arteries.

1990 • 605 citations

Inhibition of coronary artery atherosclerosis by 17-beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone.

1990 • 603 citations

Insights from the study of animals lacking functional estrogen receptor

1994 • 587 citations

The Role of Endothelium in Cardiovascular Homeostasis and Diseases

1993 • 558 citations

Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women.

1994 • 499 citations

Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.

1992 • 479 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

Identification of increased nitric oxide biosynthesis during pregnancy in rats

1993 • 394 citations

Up‐regulation of nitric oxide synthase by estradiol in human aorticendothelial cells

1995 • 352 citations

Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit.

1988 • 320 citations

Estrogen-induced uterine vasodilatation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis

1992 • 312 citations

Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium

1997 • 288 citations

Intracellular pH and Tyrosine Phosphorylation but Not Calcium Determine Shear Stress–Induced Nitric Oxide Production in Native Endothelial Cells

1996 • 287 citations

Circulating Nitric Oxide (Nitrite/Nitrate) Levels in Postmenopausal Women Substituted With 17β-Estradiol and Norethisterone Acetate

1995 • 263 citations

Canine vascular tissues are targets for androgens, estrogens, progestins, and glucocorticoids.

1982 • 237 citations

Estrogen-Binding Sites in Endothelial Cell Cultures

1978 • 229 citations

Comparison of atherosclerotic lesions and HDL-lipid levels in male, female, and testosterone-treated female mice from strains C57BL/6, BALB/c, and C3H

1987 • 216 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

1995 • 187 citations

Estrogen Enhances Basal Nitric Oxide Release in the Forearm Vasculature in Perimenopausal Women

1996 • 187 citations

Immunocytochemical Demonstration of Estrogen and Progesterone Receptors in Muscle Cells of Uterine Arteries in Rabbits and Humans*

1988 • 186 citations

Induction of nitric oxide synthases early in pregnancy

1994 • 165 citations

Bioassay of endothelium-derived relaxing factor(s): inactivation by catecholamines

1985 • 154 citations

Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae

1994 • 141 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 139 citations

Endothelium-derived relaxing factors

1995 • 119 citations

Inhibition of the development of spontaneous hypertension in SH rats by gonadectomy or estradiol.

1979 • 113 citations

91300401 Postmenopausal estrogen therapy and cardiovascular disease — Ten-year follow-up from the nurses' health study

1992 • 103 citations

Estrogen Action in the Mouse Uterus: Characterization of the Cytosol and Nuclear Receptor Systems

1979 • 101 citations

Cardiovascular Significance of Endothelium-Derived Vasoactive Factors

1992 • 97 citations

Hormone receptors of the baboon cardiovascular system. Biochemical characterization of aortic and myocardial cytoplasmic progesterone receptors.

1982 • 87 citations

Nuclear estrogen receptor molecular heterogeneity in the mouse uterus.

1988 • 46 citations

Differential effects of <scp>l</scp>‐arginine on the inhibition by N^G‐nitro‐<scp>l</scp>‐arginine methyl ester of basal and agonist‐stimulated EDRF activity

1991 • 42 citations

Cardiovascular significance of endothelium-derived vasoactive factors

1992 • 40 citations

Unstimulated release of endothelium derived relaxing factor is independent of mitochondrial ATP generation

1987 • 27 citations

Ambulatory Blood Pressure in Children Followed for 3 Years: Influence of Sex and Family History of Hypertension

1986 • 25 citations

Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women

1995 • 24 citations

17β-Estradioi and Endotheilal Nitric Oxide Synthase

1994 • 17 citations

Estrogen-Binding Sites in Endothelial Cell Cultures

1979 • 14 citations