Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Oncogenes and signal transduction

1991 • 2,816 citations

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Phosphatidylinositol 3′-kinase is activated by association with IRS-1 during insulin stimulation.

1992 • 1,030 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1992 • 692 citations

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases

1993 • 666 citations

Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1993 • 658 citations

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1990 • 650 citations

Characterization of the major protein-tyrosine-phosphatases of human placenta.

1988 • 554 citations

Activation of a Phosphotyrosine Phosphatase by Tyrosine Phosphorylation

1993 • 554 citations

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

1992 • 400 citations

Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit

1993 • 395 citations

The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp

1993 • 384 citations

Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.

1992 • 359 citations

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.

1992 • 317 citations

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma.

1992 • 231 citations

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.

1992 • 228 citations

A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains.

1993 • 219 citations

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.

1993 • 211 citations

Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2

1993 • 192 citations

Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide/SH2 domain binding

1993 • 162 citations

Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation.

1993 • 156 citations

Alternative Strategies for the Fmoc Solid‐Phase Synthesis of O⁴‐Phospho‐L‐tyrosine‐Containing Peptides

1991 • 118 citations

Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.

1993 • 110 citations

Negative Regulation of CD45 Protein Tyrosine Phosphatase Activity by Ionomycin in T Cells

1991 • 108 citations

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit.

1991 • 96 citations

Expression, purification, and characterization of SH2-containing protein tyrosine phosphatase, SH-PTP2.

1993 • 91 citations

Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1.

1993 • 73 citations

Presence of SH2 domains of phospholipase C gamma 1 enhances substrate phosphorylation by increasing the affinity toward the epidermal growth factor receptor.

1992 • 64 citations

Protein tyrosine phosphatase 1B undergoes mitosis-specific phosphorylation on serine.

1993 • 36 citations