Molecular characterization of immunoreactivities of peptides derived from chromogranin a (GE-25) and from secretogranin II (secretoneurin) in human and bovine cerebrospinal fluid

Peroxidase labelled antibody and Fab conjugates with enhanced intracellular penetration

1971 • 879 citations

The chromogranins A and B: The first 25 years and future perspectives

1992 • 653 citations

Neuropeptides in perspective: The last ten years

1991 • 620 citations

Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

1990 • 579 citations

Secretion of a Chromaffin Granule Protein, Chromogranin, from the Adrenal Gland after Splanchnic Stimulation

1967 • 523 citations

Cloning and Primary Sequence of a Mouse Candidate Prohormone Convertase PC1 Homologous to PC2, Furin, and Kex2: Distinct Chromosomal Localization and Messenger RNA Distribution in Brain and Pituitary Compared to PC2

1991 • 475 citations

Bovine chromogranin A sequence and distribution of its messenger RNA in endocrine tissues

1986 • 314 citations

Secretoneurin—a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C)

1993 • 264 citations

SECRETION FROM THE ADRENAL MEDULLA: BIOCHEMICAL EVIDENCE FOR EXOCYTOSIS

1967 • 222 citations

Chromogranin A, the major catecholamine storage vesicle soluble protein. Multiple size forms, subcellular storage, and regional distribution in chromaffin and nervous tissue elucidated by radioimmunoassay.

1984 • 217 citations

Chromogranin immunoreactivity in the central nervous system. Immunochemical characterisation, distribution and relationship to catecholamine and enkephalin pathways

1984 • 193 citations

Immunological Characterization of Secretory Proteins of Chromaffin Granules: Chromogranins A, Chromogranins B, and Enkephalin‐Containing Peptides

1985 • 160 citations

Neurons and neuroendocrine cells contain chromogranin: detection of the molecule in normal bovine tissues by immunochemical and immunohistochemical methods.

1985 • 145 citations

Secretoneurin releases dopamine from rat striatal slices: A biological effect of a peptide derived from secretogranin II (chromogranin C)

1993 • 145 citations

Attraction of human monocytes by the neuropeptide secretoneurin

1993 • 118 citations

The primary structure of rat secretogranin II deduced from a cDNA sequence

1988 • 117 citations

Distribution of secretoneurin, a peptide derived from secretogranin II, in rat brain: An immunocytochemical and radioimmunological study

1993 • 113 citations

The major tyrosine-sulfated protein of the bovine anterior pituitary is a secretory protein present in gonadotrophs, thyrotrophs, mammotrophs, and corticotrophs.

1985 • 101 citations

Identification of a peptide arising from the specific post‐translation processing of secretogranin II

1991 • 95 citations

Characterization of adenohypophysial polypeptides by two-dimensional gel electrophoresis

1981 • 90 citations

Distribution of mRNAs for Chromogranins A and B and Secretogranin II in Rat Brain

1991 • 90 citations

Chromogranin C: A Third Component of the Acidic Proteins in Chromaffin Granules

1986 • 77 citations

Neuroendocrinology of Cerebrospinal Fluid: Peptides, Steroids, and Other Hormones

1982 • 76 citations

Biochemical and functional properties of large and small dense-core vesicles in sympathetic nerves of rat and ox vas deferens

1984 • 76 citations

Chromogranins in rat brain: characterization, topographical distribution and regulation of synthesis

1990 • 73 citations

Immunohistochemical localization of secretogranin II in the rat cerebellum

1989 • 71 citations

Human and Rat Primary C‐Fibre Afferents Store and Release Secretoneurin, a Novel Neuropeptide

1994 • 71 citations

Nucleotide sequence and cellular distribution of rat chromogranin B (Secretogranin I) mRNA in the neuroendocrine system

1989 • 71 citations

Chromogranin A-like immunoreactivity in the human brain: Distribution in bulbar medulla and cerebral cortex

1990 • 65 citations

Nucleotide sequence and cellular distribution of rat chromogranin B (secretogranin I) mRNA in the neuroendocrine system

1989 • 65 citations

Immunocytochemical localization of a novel pituitary protein (7B2) within the rat brain and hypophysis.

1985 • 59 citations

Immunological characterization of the endoproteases PC1 and PC2 in adrenal chromaffin granules and in the pituitary gland

1992 • 58 citations

Distribution of Secretoneurin‐like Immunoreactivity in Comparison with Substance P‐ and Enkephalin‐like Immunoreactivities in Various Human Forebrain Regions

1993 • 53 citations

Pancreastatin distribution and plasma levels in the pig

1988 • 49 citations

Effects of haloperidol and clozapine on preprotachykinin‐A messenger RNA, tachykinin tissue levels, release and neurokinin‐1 receptors in the striato‐nigral system

1990 • 42 citations

Enkephalin-containing polypeptides in human cerebrospinal fluid

1986 • 38 citations

Bovine Posterior Pituitary: Presence of p65 (Synaptotagmin), PC1 PC2 and Secretoneurin in Large Dense Core Vesicles

1994 • 38 citations

Expression of neuropeptide processing enzymes and neurosecretory proteins in ependyma and choroid plexus epithelium

1993 • 37 citations

Detection of N‐Terminally Extended Substance P but Not of Substance P in Human Cerebrospinal Fluid: Quantitation with HPLC‐Radioimmunoassay

1988 • 36 citations

Suboccipital cerebrospinal fluid and plasma concentrations of somatostatin, neuropeptide Y and beta-endorphin in patients with common migraine

1992 • 34 citations

Distribution of secretoneurin immunoreactivity in the spinal cord and lower brainstem in comparison with that of substance P and calcitonin gene‐related peptide

1994 • 32 citations

Neuropeptides in human cerebrospinal fluid

1985 • 32 citations

THE PRESENCE OF CALCITONIN GENE-RELATED PEPTIDE IN HUMAN CEREBROSPINAL FLUID

1987 • 30 citations

Beta-endorphin and neurotensin in brainstem and cerebrospinal fluid in the sudden infant death syndrome☆

1992 • 28 citations

Secretogranin II Is Synthesized and Secreted in Astrocyte Cultures

1993 • 27 citations

Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla

1988 • 24 citations

Regional distribution of chromogranin B 420–493-like immunoreactivity in the pituitary gland and central nervous system of man, guinea-pig and rat

1989 • 24 citations

Chromogranin a immunoreactivity in human cerebrospinal fluid: Properties, relationship to noradrenergic neuronal activity, and variation in neurologic disease

1993 • 24 citations

Sites of synthesis of chromogranins A and B in the human brain

1992 • 23 citations

Analysis of proenkephalin A, proopiomelanocortin and protachykinin neuropeptides in human lumbar cerebrospinal fluid by reversed-phase high-performance liquid chromatography, radioimmunoassay and enzymolysis

1992 • 22 citations

Different degrees of processing of secretogranin II in large dense core vesicles of bovine adrenal medulla and sympathetic axons correlate with their content of soluble PC1 and PC2

1993 • 21 citations

Cerebrospinal fluid levels of immunoreactive substance P and somatostatin in patients with multiple sclerosis and inflammatory CNS disease

1990 • 21 citations

CSF chromogranin A-like immunoreactivity in schizophrenia

1991 • 19 citations

Substance P concentrations in human cerebrospinal fluid vary inversely with age

1985 • 18 citations

Different processing of chromogranin B into GAWK-immunoreactive fragments in the bovine adrenal medulla and pituitary gland

1988 • 17 citations

Measurement of lumbar CSF levels of met-enkephalin, encrypted met-enkephalin, and neuropeptide Y in normal patients and in patients with Parkinson's disease before and after autologous transplantation of adrenal medulla into the caudate nucleus.

1990 • 13 citations

CSF galanin in alcoholics, pathological gamblers, and normal controls: A negative report

1990 • 13 citations

Clinical improvement in parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin a or basic fibroblast growth factor in ventricular fluid

1991 • 11 citations

Pituitary protein 7B2-like immunoreactivity in cerebrospinal fluid: comparison with other neuropeptides.

1989 • 11 citations

Highly sensitive enzyme immunoassay for bovine chromogranin A: application for studies of regional distribution in bovine central nervous system.

1989 • 11 citations

Monoamine metabolites and neuropeptides in patients with Parkinson's disease, Huntington's chorea, Shy-Drager syndrome, and torsion dystonia.

1990 • 9 citations

Ventricular fluid neuropeptides in Parkinson's disease

1990 • 9 citations

N-terminally extended tachykinins in human cerebrospinal fluid

1993 • 7 citations

CSF galanin and neuropeptide Y immunoreactivity in progressive supranuclear palsy

1992 • 6 citations