Effects of Modafinil on Dopamine and Dopamine Transporters in the Male Human Brain
Data up to Jan 2025
Total Citations Per Year
Abstract
References (37)
Physicians Desk Reference
1994 • 2,653 citations
Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-11C-Methyl]-(−)-Cocaine PET Studies in Human Subjects
1990 • 1,412 citations
The Permeability of Capillaries in Various Organs as Determined by Use of the ‘Indicator Diffusion’ Method
1963 • 1,138 citations
Dopamine Transporter Occupancies in the Human Brain Induced by Therapeutic Doses of Oral Methylphenidate
1998 • 878 citations
Dopaminergic Role in Stimulant-Induced Wakefulness
2001 • 763 citations
Modafinil: A Review of Neurochemical Actions and Effects on Cognition
2007 • 656 citations
Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness
2000 • 484 citations
The Physicians' Desk Reference
1996 • 456 citations
“Nonhedonic” food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect
2002 • 447 citations
A Double-Blind, Placebo-Controlled Trial of Modafinil for Cocaine Dependence
2004 • 386 citations
Imaging endogenous dopamine competition with [11C]raclopride in the human brain
1994 • 378 citations
Modafinil Occupies Dopamine and Norepinephrine Transporters in Vivo and Modulates the Transporters and Trace Amine Activity in Vitro
2006 • 318 citations
Relationship between blockade of dopamine transporters by oral methylphenidate and the increases in extracellular dopamine: Therapeutic implications
2001 • 315 citations
The neuroscience of addiction
2005 • 310 citations
Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c- fos immunocytochemistry in the cat
1996 • 305 citations
Mapping cocaine binding sites in human and baboon brain in vivo
1989 • 300 citations
Evaluation of the Abuse Liability of Modafinil and Other Drugs for Excessive Daytime Sleepiness Associated with Narcolepsy
2000 • 296 citations
Dopaminergic D1and D2Receptors Are Essential for the Arousal Effect of Modafinil
2008 • 219 citations
Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI
2008 • 182 citations
Smoked Cocaine Self-Administration is Decreased by Modafinil
2007 • 172 citations
Effects of Blood Flow on [11C]Raclopride Binding in the Brain: Model Simulations and Kinetic Analysis of PET Data
1994 • 171 citations
Evaluation of the cocaine-like discriminative stimulus effects and reinforcing effects of modafinil
1996 • 157 citations
Variations in extracellular monoamines in the prefrontal cortex and medial hypothalamus after modafinil administration: a microdialysis study in rats
2001 • 148 citations
Modafinil: An antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers
1997 • 139 citations
Modafinil: Preclinical, Clinical, and Post-Marketing Surveillance—A Review of Abuse Liability Issues
2004 • 139 citations
Modafinil enhances extracellular levels of dopamine in the nucleus accumbens and increases wakefulness in rats
2006 • 93 citations
Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration
2005 • 85 citations
Synthesis of [methoxy‐3H]‐ and [methoxy‐11C]‐ labelled raclopride. Specific dopamine‐D2 receptor ligands
1987 • 85 citations
Behavioral and Cardiovascular Effects of Intravenous Methylphenidate in Normal Subjects and Cocaine Abusers
1997 • 70 citations
A Comparison of Once-Daily and Divided Doses of Modafinil in Children With Attention-Deficit/Hyperactivity Disorder
2006 • 57 citations
Mapping Neuroreceptors at work: on the Definition and Interpretation of Binding Potentials after 20 years of Progress
2005 • 55 citations
Plasma input function determination for PET using a commercial laboratory robot
1995 • 53 citations
Cerebral blood flow changes in man by wake‐promoting drug, modafinil: a randomized double blind study
2008 • 41 citations
The Science of Stimulant Abuse
2006 • 29 citations
A Comparison of Once-Daily and Divided Doses of Modafinil in Children With Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind, and Placebo-Controlled Study
2008 • 4 citations
The Science of Stimulant Abuse
2005 • 4 citations
Deleted Work
1955 • 0 citations