A phosphoprotein of Mr 47,000, defective in autosomal chronic granulomatous disease, copurifies with one of two soluble components required for NADPH:O2 oxidoreductase activity in human neutrophils.
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References (33)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT
1973 • 2,955 citations
The Biochemical Basis of Phagocytosis
1959 • 1,240 citations
Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.
1982 • 1,008 citations
Studies of the Metabolic Activity of Leukocytes from Patients with a Genetic Abnormality of Phagocytic Function*
1967 • 677 citations
The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and function
1986 • 665 citations
Leukocyte Oxidase: Defective Activity in Chronic Granulomatous Disease
1967 • 425 citations
Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.
1985 • 356 citations
Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.
1985 • 334 citations
Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.
1985 • 315 citations
Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein
1985 • 286 citations
Functional activity of enucleated human polymorphonuclear leukocytes.
1983 • 230 citations
Activation of neutrophil NADPH oxidase in a cell-free system. Partial purification of components and characterization of the activation process.
1987 • 202 citations
Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.
1985 • 193 citations
Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.
1987 • 188 citations
Subcellular localization of the human neutrophil NADPH oxidase. b-Cytochrome and associated flavoprotein.
1984 • 187 citations
A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.
1986 • 168 citations
GTP-binding proteins: One molecular machine can transduce diverse signals
1986 • 157 citations
Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.
1988 • 127 citations
Further evidence for the involvement of a phosphoprotein in the respiratory burst oxidase of human neutrophils
1986 • 111 citations
Kinetics of activation of the respiratory burst oxidase in a fully soluble system from human neutrophils.
1988 • 111 citations
Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils.
1987 • 111 citations
Chronic granulomatous disease due to a defect in the cytosolic factor required for nicotinamide adenine dinucleotide phosphate oxidase activation.
1988 • 103 citations
Purification and partial characterization of the b-type cytochrome from human polymorphonuclear leukocytes.
1985 • 97 citations
Respiratory burst oxidase from human neutrophils: purification and some properties.
1985 • 81 citations
Complementation in monocyte hybrids revealing genetic heterogeneity in chronic granulomatous disease
1984 • 80 citations
Isolation of large numbers of highly purified lymphocytes and monocytes with a modified centrifugal elutriation technique
1981 • 72 citations
Activation of protein kinase C in neutrophil cytoplasts
1985 • 68 citations
Characterization of the NADPH-dependent superoxide production activated by sodium dodecyl sulfate in a cell-free system of pig neutrophils
1987 • 58 citations
Reversible activation of NADPH oxidase in membranes of HL-60 human leukemic cells
1987 • 56 citations
Analysis of human class I antigens by two-dimensional gel electrophoresis
1983 • 40 citations
Cell-free activation of phagocyte NADPH-oxidase: Tissue and differentiation-specific expression of cytosolic cofactor activity
1987 • 12 citations
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