Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

The respiratory burst of phagocytes.

1984 • 914 citations

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

1982 • 618 citations

Fluoroaluminates activate transducin‐GDP by mimicking the γ‐phosphate of GTP in its binding site

1985 • 420 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.

1985 • 356 citations

Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase.

1984 • 342 citations

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

1984 • 335 citations

Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.

1985 • 334 citations

Receptor-Coupled Activation of Phosphoinositide-Specific Phospholipase C by an N Protein

1986 • 324 citations

Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.

1985 • 315 citations

An Inherited Abnormality of Neutrophil Adhesion

1980 • 306 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

Thyrotropin-releasing hormone activates a Ca2+-dependent polyphosphoinositide phosphodiesterase in permeable GH3 cells. GTP gamma S potentiation by a cholera and pertussis toxin-insensitive mechanism.

1986 • 197 citations

Subcellular localization of the human neutrophil NADPH oxidase. b-Cytochrome and associated flavoprotein.

1984 • 187 citations

Evidence suggesting that a novel guanine nucleotide regulatory protein couples receptors to phospholipase C in exocrine pancreas

1986 • 177 citations

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

1985 • 175 citations

Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin.

1985 • 159 citations

GTP-binding proteins: One molecular machine can transduce diverse signals

1986 • 157 citations

Regulation of human polymorphonuclear leukocyte superoxide release by cellular responses to chemotactic peptides.

1981 • 101 citations

Mechanism of inhibition of transducin GTPase activity by fluoride and aluminum.

1985 • 93 citations

Activation of the human neutrophil NADPH oxidase results in coupling of electron carrier function between ubiquinone-10 and cytochrome b559.

1985 • 48 citations

GTP and cytosol stimulate phosphoinositide hydrolysis in isolated platelet membranes

1986 • 37 citations

Cytosol Activator Protein from Rat Reticulocytes Requires the Stimulatory Guanine Nucleotide-Binding Protein for Its Actions on Adeiiylate Cyclase*

1985 • 15 citations

[40] Characterization of tubulin and microtubule-associated protein interactions with guanine nucleotides and their nonhydrolyzable analogs

1982 • 11 citations