Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution.

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

Resolution of phase ambiguity in macromolecular crystallography

1985 • 1,040 citations

Stereochemically restrained refinement of macromolecular structures

1985 • 614 citations

The treatment of errors in the isomorphous replacement method

1959 • 497 citations

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2·7 and 1·7 Å resolution

1982 • 495 citations

The use of an imaging proportional counter in macromolecular crystallography

1987 • 494 citations

The accessible surface area and stability of oligomeric proteins

1987 • 353 citations

Purine nucleoside synthesis: an efficient method employing nucleoside phosphorylases

1981 • 191 citations

Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution.

1990 • 178 citations

The glycine‐rich loop of adenylate kinase forms a giant anion hole

1986 • 143 citations

On the conformation of proteins: The handedness of the connection between parallel β-strands

1977 • 128 citations

An alternative method of solving the layer scaling equations of Hamilton, Rollett and Sparks

1966 • 109 citations

Uridine Phosphorylase from Escherichia coli. Physical and Chemical Characterization

1977 • 107 citations

Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases

1983 • 107 citations

Catabolism of thymidine in human blood platelets purification and properties of thymidine phosphorylase

1981 • 100 citations

5-Benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase

1982 • 91 citations

Specificity of pyrimidine nucleoside phosphorylases and the phosphorolysis of 5-fluoro-2'-deoxyuridine.

1980 • 79 citations

Thymidine Phosphorylase from Escherichia coli. Properties and Kinetics

1971 • 77 citations

Comparison of pharmacokinetics of 5-fluorouracil and 5-fluorouracil with concurrent thymidine infusions in a Phase I trial.

1980 • 73 citations

Cytoplasmic Uridine Phosphorylase of Rat Liver

1971 • 48 citations

[59] Thymidine phosphorylase from Escherichia coli

1978 • 47 citations

Regression of human tumors established in nude mice after continuous infusion of thymidine.

1979 • 33 citations

Oscillation camera data processing: reflecting range and prediction of partiality. 2. Monochromatized synchrotron X-radiation from a singly bent triangular monochromator

1982 • 29 citations

Correlation of substrate-stabilization patterns with proposed mechanisms for three nucleoside phosphorylases

1982 • 22 citations

Crystallization and preliminary X-ray investigation of uridine phosphorylase from Escherichia coli.

1987 • 21 citations

Irreversible enzyme inhibitors. 188. Inhibition of mammalian thymidine phosphorylase

1971 • 21 citations

Crystallization and preliminary x-ray investigation of purine-nucleoside phosphorylase from Escherichia coli.

1985 • 20 citations

Crystallization and preliminary x-ray investigation of thymidine phosphorylase from Escherichia coli.

1987 • 13 citations

Effect of thymidine on the survival of mice with EL4 tumors.

1979 • 10 citations