Autonomous activation of B and T cells in antigen-free mice

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

THE NATURAL-SELECTION THEORY OF ANTIBODY FORMATION

1955 • 700 citations

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

1979 • 451 citations

High frequency of natural autoantibodies in normal newborn mice.

1985 • 387 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Use of the Avidin-Biotin Complex for Specific Staining of Biological Membranes in Electron Microscopy

1974 • 269 citations

Reactions among IgM antibodies derived from normal, neonatal mice

1984 • 231 citations

Isotypes and specificities of immunoglobulins produced by germ‐free mice fed chemically defined ultrafiltered “antigen‐free” diet

1984 • 194 citations

From an Antigen‐Centered, Clonal Perspective of Immune Responses to an Organism‐Centered, Network Perspective of Autonomous Activity in a Self‐Referential Immune System

1984 • 143 citations

Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies

1980 • 136 citations

The high idiotypic connectivity of “natural” newborn antibodies is not found in adult mitogen‐reactive B cell repertoires

1986 • 119 citations

Two-step separation of human peripheral blood monocytes on discontinuous density gradients of colloidal silica-polyvinylpyrrolidinone

1977 • 77 citations

Natural effector T lymphocytes in normal mice.

1985 • 70 citations

Frequencies of background immunoglobulin-secreting cells in mice as a function of organ, age, and immune status

1981 • 59 citations

A "Trans" Perspective on the Control of Immunoglobulin C Gene Expression

1982 • 53 citations

The Uniqueness and Boundaries of the Idiotypic Self

1984 • 32 citations

Natural autoantibodies to the fore — forbidden clones to the rear?

1983 • 32 citations

The production of membrane or secretory forms of immunoglobulins is regulated by C-gene-specific signals

1982 • 25 citations

Effect of anti‐γ₃ antibodies on immunoglobulin isotype expression in lipopolysaccharide‐stimulated cultures of mouse spleen cells

1983 • 21 citations

Oxygen Consumption and Thyroid Hormones in Germfree Mice Fed Glucose-Amino Acid Liquid Diet

1982 • 19 citations