Nucleus Accumbens Dopamine and the Regulation of Effort in Food-Seeking Behavior: Implications for Studies of Natural Motivation, Psychiatry, and Drug Abuse
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References (69)
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
1998 • 3,973 citations
A psychomotor stimulant theory of addiction.
1987 • 2,704 citations
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex
2002 • 2,076 citations
The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
1999 • 1,420 citations
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
1997 • 1,234 citations
Neuroleptics and operant behavior: The anhedonia hypothesis
1982 • 1,021 citations
Nucleus accumbens shell and core dopamine: differential role in behavior and addiction
2002 • 957 citations
Impulsive Choice Induced in Rats by Lesions of the Nucleus Accumbens Core
2001 • 908 citations
Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine
2002 • 783 citations
On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine
1977 • 733 citations
The involvement of nucleus accumbens dopamine in appetitive and aversive motivation
1994 • 580 citations
Behavioral functions of nucleus accumbens dopamine: Empirical and conceptual problems with the anhedonia hypothesis
1997 • 525 citations
Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure
1994 • 446 citations
Incentive Sensitization by Previous Amphetamine Exposure: Increased Cue-Triggered “Wanting” for Sucrose Reward
2001 • 435 citations
Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat.
1978 • 421 citations
Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food choice procedure
1991 • 417 citations
A COST‐BENEFIT ANALYSIS OF DEMAND FOR FOOD
1988 • 344 citations
Complex motor and sensorimotor functions of striatal and accumbens dopamine: involvement in instrumental behavior processes
1992 • 284 citations
Dopamine and depression: A review of recent evidence. I. Empirical studies
1983 • 267 citations
Nucleus accumbens dopamine depletions make rats more sensitive to high ratio requirements but do not impair primary food reinforcement
1999 • 262 citations
Nucleus accumbens dopamine depletions alter relative response allocation in a T-maze cost/benefit task
1996 • 235 citations
Decreased intracranial self-stimulation after neuroleptics or 6-hydroxydopamine: Evidence for mediation by motor deficits rather than by reduced reward
1976 • 227 citations
Effects of selective dopamine D1 or D2 receptor blockade within nucleus accumbens subregions on ingestive behavior and associated motor activity
2002 • 221 citations
D1 or D2 antagonism in nucleus accumbens core or dorsomedial shell suppresses lever pressing for food but leads to compensatory increases in chow consumption
2001 • 220 citations
Dopamine gating of glutamatergic sensorimotor and incentive motivational input signals to the striatum
2002 • 206 citations
Sensitization of Midbrain Dopamine Neuron Reactivity Promotes the Pursuit of Amphetamine
2002 • 205 citations
Neural integrative activities of nucleus accumbens subregions in relation to learning and motivation
1999 • 196 citations
Nucleus accumbens dopamine depletions make animals highly sensitive to high fixed ratio requirements but do not impair primary food reinforcement
2001 • 196 citations
Ventrolateral striatal dopamine depletions impair feeding and food handling in rats
1993 • 178 citations
Nucleus accumbens dopamine depletions in rats affect relative response allocation in a novel cost/benefit procedure
1994 • 171 citations
Different effects of nucleus accumbens and ventrolateral striatal dopamine depletions on instrumental response selection in the rat
1993 • 169 citations
Vacuous jaw movements and feeding deficits in rats with ventrolateral striatal dopamine depletion: possible relation to parkinsonian symptoms
1991 • 168 citations
Behavior-Relevant Changes in Nucleus Accumbens Dopamine Transmission Elicited by Food Reinforcement: An Electrochemical Study in Rat
1996 • 163 citations
Role of nucleus accumbens dopamine D1 and D2 receptors in instrumental and Pavlovian paradigms of conditioned reward
2000 • 155 citations
The behavioral neurochemistry of motivation: methodological and conceptual issues in studies of the dynamic activity of nucleus accumbens dopamine
1996 • 155 citations
Involvement of nucleus accumbens dopamine in the motor activity induced by periodic food presentation: a microdialysis and behavioral study
1992 • 153 citations
EFFECTS OF MESOLIMBIC DOPAMINE DEPLETION ON RESPONDING MAINTAINED BY COCAINE AND FOOD
1994 • 153 citations
The Psychopharmacology of Energy and Fatigue
2002 • 151 citations
Dopaminergic involvement in activational aspects of motivation: Effects of haloperidol on schedule-induced activity, feeding, and foraging in rats
1988 • 146 citations
Dopamine antagonists alter response allocation but do not suppress appetite for food in rats: contrast between the effects of SKF 83566, raclopride, and fenfluramine on a concurrent choice task
2002 • 143 citations
The role of brain dopamine in response initiation: effects of haloperidol and regionally specific dopamine depletions on the local rate of instrumental responding
1993 • 137 citations
Nucleus accumbens dopamine and work requirements on interval schedules
2002 • 125 citations
Effects of d-amphetamine and apomorphine upon operant behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens.
1983 • 120 citations
A microdialysis study of nucleus accumbens core and shell dopamine during operant responding in the rat
1998 • 108 citations
Positive relationship between activity in a novel environment and operant ethanol self-administration in rats
2002 • 108 citations
Effects of Raclopride in the Nucleus Accumbens on Ethanol Seeking and Consumption
2001 • 101 citations
Effects of dopamine receptor antagonists on sucrose consumption and preference
1989 • 97 citations
Different effects of haloperidol and extinction on instrumental behaviours
1986 • 97 citations
The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: A neurochemical and behavioral study
1993 • 95 citations
Cocaine-seeking by rats: regulation, reinforcement and activation
2000 • 89 citations
The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: Contrasts with the effects of extinction
1995 • 75 citations
Conditioned appetitive stimulus increases extracellular dopamine in the nucleus accumbens of the rat
2002 • 75 citations
Nucleus accumbens dopamine and rate of responding: Neurochemical and behavioral studies
1999 • 75 citations
Low doses of haloperidol interfere with rat tongue extensions during licking: A quantitative analysis.
1992 • 72 citations
Symmetrical effects of amphetamine and alpha-flupenthixol on conditioned punishment and conditioned reinforcement: contrasts with midazolam
1997 • 71 citations
Different behavioral functions of dopamine in the nucleus accumbens and ventrolateral striatum: a microdialysis and behavioral investigation
1999 • 63 citations
Substance dependence as a compulsive behavior
1998 • 60 citations
Low doses of haloperidol interfere with rat tongue extensions during licking: A quantitative analysis.
1992 • 56 citations
Dopamine in the nucleus accumbens: cellular actions, drug- and behavior-associated fluctuations, and a possible role in an organism's adaptive activity
2002 • 51 citations
AcuteLead Acetate Administration Potentiates Ethanol‐Induced Locomotor Activity in Mice: The Role of Brain Catalase
1999 • 47 citations
Sexually conditioned incentives:
2002 • 45 citations
Treatment Strategies in Amotivated Patients
1997 • 44 citations
Both the shell of the nucleus accumbens and the central nucleus of the amygdala support amphetamine self-administration in rats
2002 • 39 citations
Schedule-dependent effects of haloperidol and amphetamine: multiple-schedule task shows within-subject effects
2001 • 34 citations
Increase in accumbal dopaminergic transmission correlates with response cost not reward of hypothalamic stimulation
2002 • 28 citations
Haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: Reevaluation of the anhedonia hypothesis of dopamine blocking.
2002 • 21 citations
Haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: Reevaluation of the anhedonia hypothesis of dopamine blocking.
2002 • 18 citations
An update of fowler and das: Anticholinergic reversal of haloperidol-induced, within-session decrements in rats' lapping behavior
1996 • 14 citations
Complex response competition and dopamine blocking: choosing of high cost sucrose solution versus low cost water in rats.
1995 • 12 citations