Human recombinant interleukin-1α protection against the lethality of endotoxin and experimental sepsis in mice

Biology of interleukin 1

1988 • 1,547 citations

Sepsis and septic shock—A review of laboratory models and a proposal

1980 • 1,441 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Laboratory models of sepsis and septic shock

1990 • 539 citations

A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection.

1988 • 241 citations

Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection.

1989 • 196 citations

Interleukin 1 pretreatment decreases ischemia/reperfusion injury.

1990 • 152 citations

Enhanced resistance of mice to bacterial infection induced by recombinant human interleukin-1a

1987 • 146 citations

Recombinant murine interleukin-1 alpha enhancement of nonspecific antibacterial resistance

1987 • 118 citations

Prevention and treatment of endotoxin and sepsis lethality with recombinant human tumor necrosis factor.

1989 • 85 citations

Augmentation of host resistance to microbial infections by recombinant human interleukin-1 alpha

1988 • 53 citations

The biological activities of interleukin-1

1989 • 43 citations

Protective effects and role of endotoxin in experimental septicemia.

1984 • 31 citations

The Effect of Interleukin 1α on Survival in a Murine Model of Burn Wound Sepsis

1990 • 30 citations

Tumor necrosis factor and interleukin-1 protection against the lethal effects of tumor necrosis factor.

1991 • 24 citations

Prevention of fatal infections by recombinant human interleukin 1 alpha in normal and anticancer drug-treated mice.

1990 • 22 citations

Recombinant interleukin-1 stimulates clearance of Escherichia coli K1 bacteraemia

1989 • 19 citations