Stress reactivity of the brain noradrenergic system in three rat strains differing in their neuroendocrine and behavioral responses to stress: implications for susceptibility to stress-related neuropsychiatric disorders

Psychopharmacology: The Fourth Generation of Progress

1995 • 2,920 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

Role of locus coeruleus in attention and behavioral flexibility

1999 • 867 citations

Mechanisms of stress: A dynamic overview of hormonal and behavioral homeostasis

1992 • 867 citations

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

1980 • 813 citations

Corticotropin-releasing factor, norepinephrine, and stress

1999 • 623 citations

Corticosteroids in relation to fear, anxiety and psychopathology

2001 • 606 citations

A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

1989 • 579 citations

Discharge of noradrenergic locus coeruleus neurons in behaving rats and monkeys suggests a role in vigilance

1991 • 575 citations

Abnormal Noradrenergic Function in Posttraumatic Stress Disorder

1993 • 566 citations

A role for corticotropin releasing factor and urocortin in behavioral responses to stressors

1999 • 527 citations

A multiple-test study of anxiety-related behaviours in six inbred rat strains

1997 • 497 citations

Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus

1990 • 400 citations

Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. I. Acutely presented stressful and nonstressful stimuli

1987 • 374 citations

Strain Differences in the Behavioral Effects of Antidepressant Drugs in the Rat Forced Swimming Test

2000 • 338 citations

The Extended Amygdala: Are the Central Nucleus of the Amygdala and the Bed Nucleus of the Stria Terminalis Differentially Involved in Fear versus Anxiety?

1999 • 332 citations

Facilitation of Immunoreactive Corticotropin-Releasing Factor Secretion into the Hypophysial-Portal Circulation after Activation of Catecholaminergic Pathways or Central Norepinephrine Injection*

1987 • 324 citations

The Locus Coeruleus as a Site for Integrating Corticotropin‐Releasing Factor and Noradrenergic Mediation of Stress Responsesa

1993 • 297 citations

The Endocrinology of Melancholic and Atypical Depression: Relation to Neurocircuitry and Somatic Consequences

1999 • 295 citations

Conditioned fear and startle magnitude: Effects of different footshock or backshock intensities used in training.

1978 • 276 citations

Hypothalamic-Pituitary-Adrenal Response to Chronic Stress in Five Inbred Rat Strains: Differential Responses Are Mainly Located at the Adrenocortical Level

1996 • 269 citations

Noradrenergic agonists and antagonists: Effects on conditioned fear as measured by the potentiated startle paradigm

1979 • 263 citations

Open field, learned helplessness, conditioned defensive burying, and forced-swim tests in WKY rats

1994 • 260 citations

The Bed Nucleus of the Stria Terminalis: A Target Site for Noradrenergic Actions in Opiate Withdrawal

1999 • 252 citations

Modulatory effects of norepinephrine in the lateral bed nucleus of the stria terminalis on behavioral and neuroendocrine responses to acute stress

2002 • 244 citations

Anatomy of brain alpha₁‐adrenergic receptors: In vitro autoradiography with [¹²⁵I]‐heat

1985 • 238 citations

The noradrenergic system in pathological anxiety: a focus on panic with relevance to generalized anxiety and phobias

1999 • 237 citations

Involvement of the Bed Nucleus of the Stria Terminalis in Tonic Regulation of Paraventricular Hypothalamic CRH and AVP mRNA Expression

1994 • 234 citations

Conditioned fear and startle magnitude: Effects of different footshock or backshock intensities used in training.

1978 • 184 citations

Sensitive pituitary-adrenal responsiveness to varying intensities of psychological stimulation

1978 • 182 citations

Excitatory Influence of the Locus Coeruleus in Hypothalamic‐Pituitary‐Adrenocortical Axis Responses to Stress

1999 • 160 citations

The hidden patient: unrecognized panic disorder.

1990 • 151 citations

Depressive behavior and stress ulcer in Wistar Kyoto rats

1993 • 146 citations

Pharmacological Characterisation of a Modified Social Interaction Model of Anxiety in the Rat

1985 • 132 citations

Monoamine innervation of bed nucleus of stria terminalis: An electron microscopic investigation

1992 • 130 citations

Behavioral reactivity to stress

2002 • 128 citations

Anxiogenic action of caffeine: an experimental study in rats

1997 • 124 citations

Behavioral reactivity to social and nonsocial stimulations: a multivariate analysis of six inbred rat strains.

1997 • 116 citations

Effects of immobilization on in vivo release of norepinephrine in the bed nucleus of the stria terminalis in conscious rats

1995 • 107 citations

Glucocorticoid negative feedback on the HPA axis in five inbred rat strains

1998 • 103 citations

A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses

1998 • 102 citations

Strain differences in hypothalamic-pituitary-adrenal activity and stress ulcer

1994 • 102 citations

Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. I. Thermoregulatory challenge

1987 • 102 citations

Dexamethasone suppresses pituitary-adrenal but not behavioral effects of centrally administered CRF

1986 • 98 citations

Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol.

1988 • 95 citations

Bladder distention activates noradrenergic locus coeruleus neurons by an excitatory amino acid mechanism

1992 • 94 citations

Catecholamine-CRF synaptic interaction in a septal bed nucleus: Afferents of neurons in the bed nucleus of the stria terminalis

1994 • 92 citations

Antagonistic effects of caffeine and yohimbine in animal tests of anxiety

1989 • 85 citations

Brain corticotropin-releasing factor immunoreactivity and receptors in five inbred rat strains: relationship to forced swimming behaviour

1997 • 72 citations

Single-unit and physiological analyses of brain norepinephrine function in behaving animals

1991 • 68 citations

Physiological and neurochemical aspects of corticotropin-releasing factor actions in the brain: the role of the locus coeruleus.

1998 • 68 citations

Individual differences in behavioral reactivity: correlation with stress-induced norepinephrine efflux in the hippocampus of Sprague-Dawley rats

1999 • 66 citations

Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wistar and Wistar-Kyoto rats

2000 • 63 citations

Effects of physiological manipulations on locus coeruleus neuronal activity in freely moving cats. III. Glucoregulatory challenge

1987 • 58 citations

A combined immunocytochemical and retrograde tracing study of noradrenergic connections between the caudal medulla and bed nuclei of the stria terminalis

1995 • 48 citations

Hypertensive rats exhibit heightened expression of corticotropin-releasing factor in activated central neurons in response to restraint stress

1999 • 45 citations

Strain differences in rat adrenal biosynthetic enzymes and stress-induced increases in plasma catecholamines

1979 • 39 citations

A neuroanatomy of stress.

1995 • 29 citations

Locus coeruleus electrophysiological activity and responsivity to corticotropin-releasing factor in inbred hypertensive and normotensive rats

1997 • 26 citations