A genetic and multifactorial analysis of anxiety-related behaviours in Lewis and SHR intercrosses

Introduction to Quantitative Genetics.

1982 • 22,508 citations

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

The use of a plus-maze to measure anxiety in the mouse

1987 • 2,571 citations

Development of a Strain of Spontaneously Hypertensive Rats

1963 • 2,492 citations

Tests for emotionality in rats and mice: A review

1973 • 1,561 citations

Ethologically-based animal models of anxiety disorders

1990 • 841 citations

Ethopharmacological analysis of rat behavior on the elevated plus-maze

1994 • 823 citations

Behavioral genetics, a primer

1980 • 722 citations

Sex differences in animal tests of anxiety

1991 • 576 citations

Stress and emotionality: a multidimensional and genetic approach

1997 • 508 citations

A multiple-test study of anxiety-related behaviours in six inbred rat strains

1997 • 497 citations

Differences in fear motivated behaviors among inbred mouse strains

1993 • 450 citations

A Simple Genetic Basis for a Complex Psychological Trait in Laboratory Mice

1995 • 447 citations

Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats

1996 • 414 citations

Behavioral genetics: A primer

1990 • 380 citations

The Maudsley Reactive and Nonreactive strains of rats: A survey

1975 • 344 citations

Emotional behavior in the rat. III. The relationship between emotionality and ambulatory activity.

1936 • 322 citations

5HT drugs in animal models of anxiety

1993 • 261 citations

Polygenic disease: methods for mapping complex disease traits

1995 • 239 citations

Identification of sex–specific quantitative trait loci controlling alcohol preference in C57BL/6 mice

1996 • 188 citations

Emotionality in male and female rodents: A reply to Archer

1979 • 185 citations

Anxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests

1997 • 174 citations

5-HT receptors as targets for the development of novel anxiolytic drugs: models, mechanisms and future directions

1993 • 168 citations

5-HT2C (HTR2C)serotonin receptor gene polymorphism associated with the human personality trait of reward dependence: Interaction with dopamine D4 receptor (D4DR) and dopamine D3 receptor (D3DR) polymorphisms

1997 • 162 citations

Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure.

1990 • 157 citations

Stressful environmental stimuli increase extracellular DOPAC levels in the prefrontal cortex of hypoemotional (Roman high-avoidance) but not hyperemotional (Roman low-avoidance) rats. An in vivo voltammetric study

1988 • 137 citations

Open field and elevated plus-maze: A behavioural comparison between spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats and the effects of chlordiazepoxide

1987 • 133 citations

Quantitative Trait Loci in Genetically Hypertensive Rats

1996 • 122 citations

Differential responsiveness of inbred strains of rats to antidepressants in the forced swimming test: are Wistar Kyoto rats an animal model of subsensitivity to antidepressants?

1996 • 102 citations

The biological basis of anxiety

1985 • 99 citations

Male Fischer 344 and Lewis rats display differences in locomotor reactivity, but not in anxiety-related behaviours: relationship with the hippocampal serotonergic system

1995 • 96 citations

Dissociation of genetic hyperactivity and hypertension in SHR.

1983 • 93 citations

Daily mood states and ambulatory blood pressure

1997 • 87 citations

Gender bias in the preclinical psychopharmacology of anxiety: male models for (predominantly) female disorders

1995 • 80 citations

Quantitative Trait Loci Affecting Methamphetamine Responses in BXD Recombinant Inbred Mouse Strains

1997 • 79 citations

Evidence that the Behaviors in the Mouse Defense Test Battery Relate to Different Emotional States: A Factor Analytic Study

1996 • 76 citations

Psychobiogenetics: adapted tools for the study of the coupling between behavioral and neuroendocrine traits of emotional reactivity

1994 • 75 citations

PSYCHOGENETICS OF EMOTIONALITY IN THE RAT*

1969 • 69 citations

Spontaneously Hypertensive Rat Y Chromosome Increases Indexes of Sympathetic Nervous System Activity

1997 • 65 citations

Behavioral and neuroendocrine reactivity to stress in the WKHA/WKY inbred rat strains: a multifactorial and genetic analysis

1996 • 65 citations

Elevated plus-maze behavior in adult offspring of selectively bred rats

1996 • 65 citations

Behavioral reactivity in spontaneously hypertensive rats

1985 • 62 citations

Brain Metabolism of Progesterone, Coping Behaviour and Emotional Reactivity in Male Rats from Two Psychogenetically Selected Lines

1997 • 61 citations

Tsukuba High- and Low-Emotional strains of rats (Rattus norvegicus): An overview

1994 • 60 citations

Factor-derived subsyndromes of schizophrenia and familial morbid risks

1997 • 58 citations

Maudsley reactive and nonreactive rats differ only in some tasks reflecting emotionality

1992 • 50 citations

Paradoxical differences in animal models of anxiety among the Roman rat lines

1994 • 50 citations

Genetic analysis of the relationships between behavioral and neuroendocrine traits in roman high and low avoidance rat lines

1995 • 50 citations

Factor analysis of open-field behavior in the rat (Rattus norvegicus): application of the three-way PARAFAC model to a longitudinal data set

1994 • 49 citations

Comparison of anxiety measured in the elevated plus-maze, open-field and social interaction tests between spontaneously hypertensive rats and Wistar EPM-1 rats.

1993 • 47 citations

Stability and change in the inheritance of behaviour in rats: a further analysis of statistics from a diallel cross

1966 • 47 citations

The SHR Exhibits Less “Anxiety” but Increased Sensitivity to the Anticonflict Effect of Clonidine Compared to Normotensive Controls

1989 • 46 citations

Differential behavioral response in LEW/N and F344/N rats: Effects of corticotropin releasing hormone

1992 • 44 citations

Origins of individual differences in anxiety proneness: a twin/adoption study of the anxiety‐related scales from the Karolinska Scales of Personality (KSP)

1996 • 41 citations

Psychoneuroendocrine profile associated with hypertension or hyperactivity in spontaneously hypertensive rats

1993 • 40 citations

Genetic factors regulate processes related to anxiety in mice

1997 • 37 citations

Open-field behavior in mice: Genetic analysis of repeated measures

1968 • 22 citations

Evaluating activity and emotional reactivity in a hexagonal tunnel maze: Correlational and factorial analysis from a study with the Roman/Verh rat lines

1994 • 15 citations

Failure to find behavioural differences between lean and obese Zucker rats exposed to novel environments.

1994 • 14 citations

COSEGREGATION OF THE NEW REGION ON CHROMOSOME 3 WITH SALT‐INDUCED HYPERTENSION IN FEMALE F2 PROGENY FROM STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE AND WISTAR‐KYOTO RATS

1996 • 13 citations

Environmentally-Reguiated Genes of Hypertension

1996 • 12 citations

Les bases de la génétique quantitative : Définition et mesure des paramètres du croisement

1992 • 2 citations