Calcium Deposit Formation and Glial Reaction in Rat Brain after Ibotenic Acid‐induced Basal Forebrain Lesion

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

1999 • 3,597 citations

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1983 • 3,028 citations

A rapid radiochemical method for the determination of choline acetyltransferase

1975 • 2,406 citations

Calbindin D-28k and parvalbumin in the rat nervous system

1990 • 2,068 citations

A Histochemical Method for Localizing Cholinesterase Activity.

1949 • 1,203 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

Cellular localization of a metabotropic glutamate receptor in rat brain

1992 • 539 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function

1994 • 425 citations

Astrocytes Block Axonal Regeneration in Mammals by Activating the Physiological Stop Pathway

1987 • 400 citations

Increased monoamine oxidase b activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography

1994 • 361 citations

Frequenin—A novel calcium-binding protein that modulates synaptic efficacy in the drosophila nervous system

1993 • 360 citations

Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats

1987 • 352 citations

The effect of age on the activity and molecular properties of human brain monoamine oxidase

1980 • 342 citations

The pathological association between down syndrome and Alzheimer disease

1988 • 334 citations

Quantitative enzyme radioautography with 3H-Ro 41-1049 and 3H-Ro 19- 6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain

1992 • 332 citations

HISTOCHEMICAL METHODS FOR CALCIUM

1958 • 311 citations

Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type

1980 • 254 citations

Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats.

1985 • 249 citations

Glutamate receptors activate Ca2+ mobilization and Ca2+ influx into astrocytes.

1990 • 239 citations

The effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on the acquisition and retention of a conditional visual discrimination: Implications for cholinergic hypotheses of learning and memory

1987 • 183 citations

Macrophage and Astrocyte Populations in Relation to [³H]PK 11195 Binding in Rat Cerebral Cortex following a Local Ischaemic Lesion

1991 • 178 citations

Comparative effects of quisqualic and ibotenic acid-induced lesions of the substantia innominata and globus pallidus on the acquisition of a conditional visual discrimination: Differential effects on cholinergic mechanisms

1989 • 162 citations

The significance of the incidental finding of basal ganglia calcification on computed tomography.

1981 • 148 citations

An analysis of feeding and sensorimotor abilities of rats after decortication.

1981 • 139 citations

Expression of monoamine oxidase B activity in astrocytes of senile plaques

1990 • 128 citations

Calcification of the basal ganglia

1979 • 128 citations

Imaging of human brain lesions with an ω₃ site radioligand

1988 • 125 citations

Peripheral benzodiazepine binding sites in Alzheimer's disease frontal and temporal cortex

1991 • 115 citations

ASTROGLIAL CELL CONTRIBUTIONS TO NEURONAL SURVIVAL AND NEURITIC GROWTH

1986 • 114 citations

Microglial—Neuronal interactions

1993 • 111 citations

Diffuse neurofibrillary tangles with calcification: a new presenile dementia.

1994 • 103 citations

Familial idiopathic striopallidodentate calcifications

1989 • 98 citations

Bilateral striopallidodentate calcinosis: Cerebrospinal fluid, imaging, and cerebrospinal fluid, imaging, and electrophysiological studies

1992 • 98 citations

Divergent effects of astroglial and microglial secretions on neuron growth and survival

1992 • 95 citations

Calcification of axons in experimental spinal cord trauma

1977 • 94 citations

REACTIVE GLIOSIS

1986 • 81 citations

Similar memory impairments found in medial septal-vertical diagonal band of Broca and nucleus basalis lesioned rats: Are memory defects induced by nucleus basalis lesions related to the degree of non-specific subcortical cell loss?

1990 • 80 citations

In Vitro Quantitative Autoradiography of [³H]‐L‐Deprenyl and [³H]‐PK 11195 Binding Sites in Human Epileptic Hippocampus

1992 • 52 citations

Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.

1991 • 45 citations

Age-related recurrence of basal forebrain lesion-induced cholinergic deficits

1987 • 44 citations

Comparison of behavioral effects of nucleus basalis magnocellularis lesions and somatosensory cortex ablation in the rat

1989 • 44 citations

Regional Calcium Accumulation and Cation Shifts in Rat Brain by Kainate

1984 • 43 citations

Differential brain area vulnerability to long-term subcortical excitotoxic lesions

1995 • 41 citations

Widespread neuronal degeneration after ibotenic acid lesioning of cholinergic neurons in the nucleus basalis revealed by in situ hybridization

1992 • 37 citations

Ibotenic acid-induced calcium deposits in rat substantia nigra

1992 • 33 citations

Iron accumulation in the rat basal ganglia after excitatory amino acid injections—Dissociation from neuronal loss

1992 • 26 citations

Inhibition of N-methyl-d-aspartate evoked sodium flux by MK-801

1988 • 25 citations

Calcium deposits develop in rat substantia nigra but not striatum several weeks after local ibotenic acid injection

1990 • 20 citations