REACTIVE GLIOSIS

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

Monoclonal antibody to a plasma membrane antigen of neurons.

1979 • 965 citations

Neuronal plasticity in the septal nuclei of the adult rat

1969 • 818 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics

1983 • 758 citations

LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA

1968 • 706 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system

1981 • 631 citations

Autoradiographic investigation of cell proliferation in the brains of rats and cats

1963 • 584 citations

Renewal of Cell Populations

1956 • 564 citations

Synapse replacement in the nervous system of adult vertebrates.

1981 • 545 citations

Neural grafting in the mammalian CNS

1985 • 536 citations

Transition between immature radial glia and mature astrocytes studied with a monoclonal antibody to vimentin

1984 • 536 citations

A quantitative investigation of the development of collateral reinnervation after partial deafferentation of the septal nuclei

1973 • 496 citations

Transplantation of central and peripheral monoamine neurons to the adult rat brain: Techniques and conditions for survival

1976 • 490 citations

THE ASTROGLIAL RESPONSE TO STABBING. IMMUNOFLUORESCENCE STUDIES WITH ANTIBODIES TO ASTROCYTE‐SPECIFIC PROTEIN (GFA) IN MAMMALIAN AND SUBMAMMALIAN VERTEBRATES

1976 • 473 citations

Electron microscopic identification of three classes of oligodendrocytes and a preliminary study of their proliferative activity in the corpus callosum of young rats

1970 • 465 citations

Spinal Cord Reconstruction

1983 • 437 citations

Extensive elongation of axons from rat brain into peripheral nerve grafts

1982 • 436 citations

Glia are a unique substrate for the in vitro growth of central nervous system neurons

1984 • 425 citations

Intracerebral Neural Implants: Neuronal Replacement and Reconstruction of Damaged Circuitries

1984 • 416 citations

Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system.

1981 • 410 citations

Fibrillary astrocytes proliferate in response to brain injury

1979 • 399 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Laminin is produced by early rat astrocytes in primary culture.

1983 • 389 citations

Glial cells in the enteric nervous system contain glial fibrillary acidic protein

1980 • 379 citations

Adult rat brain astrocytes support survival of both NGF-dependent and NGF-insensitive neurones

1979 • 378 citations

Localization of vimentin, the nonspecific intermediate filament protein, in embryonal glia and in early differentiating neurons

1982 • 378 citations

Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system

1979 • 374 citations

Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct

1984 • 370 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve I. Cell proliferation

1976 • 364 citations

Glial heterogeneity may define the three-dimensional shape of mouse mesencephalic dopaminergic neurones

1984 • 326 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. II. Time of origin

1976 • 315 citations

Laminin is induced in astrocytes of adult brain by injury.

1984 • 315 citations

Regeneration in the Central Nervous System

1956 • 309 citations

Sensory neurons in culture: Changing requirements for survival factors during embryonic development

1980 • 302 citations

Deposition of Scar Tissue in the Central Nervous System

1983 • 285 citations

ORIGIN OF BRAIN MACROPHAGES IN THE MOUSE

1963 • 282 citations

The proliferation of astrocytes around a needle wound in the rat brain.

1970 • 271 citations

New Neuronal Growth Factors

1984 • 269 citations

Differentiation of a bipotential glial progenitor cell in single cell microculture

1985 • 262 citations

Schwann cells of the olfactory nerves contain glial fibrillary acidic protein and resemble astrocytes

1982 • 251 citations

Nerve regeneration model and trophic factors in vivo

1982 • 240 citations

Electron microscopic studies of wallerian degeneration in rat optic nerves. I. The multipotential glia

1970 • 234 citations

Preferential outgrowth of central nervous system neurites on astrocytes and Schwann cells as compared with nonglial cells in vitro.

1985 • 232 citations

Two glial cell lineages diverge prenatally in rat optic nerve

1984 • 232 citations

Astrocyte-like glia in the peripheral nervous system: an immunohistochemical study of enteric glia

1983 • 229 citations

Glia-Induced Morphological Differentiation in Neuroblastoma Cells

1973 • 228 citations

The in vitro differentiation of a bipotential glial progenitor cell.

1984 • 227 citations

Glial Fibrillary Acidic Protein (GFA) in Normal Neural Cells and in Pathological Conditions

1980 • 227 citations

Electron microscopic studies of Wallerian degeneration in rat optic nerves. II. Astrocytes, oligodendrocytes and adventitial cells

1970 • 208 citations

Is reactive gliosis a property of a distinct subpopulation of astrocytes?

1986 • 206 citations

Electron microscopic features and proliferation of astrocytes in the corpus callosum of the rat

1969 • 205 citations

Regeneration of Axons in the Vertebrate Central Nervous System

1956 • 200 citations

Neuronotrophic activity in brain wounds of the developing rat. Correlation with implant survival in the wound cavity

1983 • 197 citations

Proliferative and migratory activity of glial cells in the partially deafferented hippocampus

1979 • 197 citations

New Neurotrophic Factors

1983 • 190 citations

The cellular reaction to wallerian degeneration in the central nervous system of the cat

1969 • 190 citations

Trophic and Specifying Factors Directed to Neuronal Cells

1981 • 186 citations

The survival of brain transplants is enhanced by extracts from injured brain.

1984 • 185 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

Proliferation of mature oligodendrocytes after trauma to the central nervous system

1984 • 179 citations

The Origin and Nature of Microglia

1981 • 178 citations

In vivo and in vitro differentiation of neurons and astrocytes in the rat embryo

1981 • 171 citations

INCORPORATION OF THYMIDINE-H3 BY CELLS IN NORMAL AND INJURED MOUSE SPINAL CORD

1962 • 168 citations

New factor released by cultured glioma cells supporting survival and growth of sensory neurones

1978 • 167 citations

Neuroglial reactions secondary to wallerian degeneration in the optic nerve of the postnatal rat: Ultrastructural and quantitative study

1977 • 166 citations

An autoradiographic study of neuronal development, vascularization and glial cell migration from hippocampal transplants labelled in intermediate explant culture

1984 • 160 citations

Expression of Glial Fibrillary Acidic Protein in Immature Oligodendroglia

1984 • 153 citations

Glial fibrillary acidic protein in cryogenic lesions of the rat brain

1981 • 151 citations

Two forms of cerebellar glial cells interact differently with neurons in vitro.

1984 • 148 citations

Competence of nerve tissue as distal insert promoting nerve regeneration in a silicone chamber

1984 • 145 citations

Development, reactivity and GFA immunofluorescence of astroglia-containing monolayer cultures from rat cerebrum

1979 • 142 citations

Mitogens for glial cells: a comparison of the response of cultured astrocytes, oligodendrocytes and schwann cells

1981 • 137 citations

Mitotic division of neuroglia in the normal adult rat

1967 • 137 citations

Temporal changes of neuronotrophic activities accumulating in vivo within nerve regeneration chambers

1983 • 136 citations

The Reactive Astrocyte

1981 • 136 citations

An autoradiographic study of cellular proliferation in degenerating rat optic nerve

1971 • 129 citations

The fine structure of pulse labeled (³H‐thymidine cells) in degenerating rat optic nerve

1975 • 129 citations

Astrocyte cultures from adult rat brain. Derivation, characterization and neurotrophic properties of pure astroglial cells from corpus callosum

1982 • 125 citations

Glial Fibrillary Acidic Protein

1981 • 121 citations

Astrocyte cell lineage. II. Mouse fibrous astrocytes and reactive astrocytes in cultures have vimentin- and GFP-containing intermediate filaments

1983 • 112 citations

Development of embryonic spinal cord transplants in the rat

1983 • 111 citations

Differences between adult and neonatal rats in their astroglial response to spinal injury

1984 • 110 citations

Gliogenesis of astrocytes and oligodendrocytes in the neocortical grey and white matter of the adult rat: Electron microscopic analysis of light radioautographs

1980 • 101 citations

Identification of the pituicytes as astroglial cells by indirect immunofluorescence-staining for the glial fibrillary acidic protein

1981 • 100 citations

Correlation of glial proliferation with age in the mouse brain

1968 • 99 citations

Autoradiographic investigations of glial proliferation in the brain of adult mice. II. Cycle time and mode of proliferation of neuroglia and endothelial cells

1975 • 96 citations

Autoradiographic investigations of glial proliferation in the brain of adult mice. The DNA synthesis phase of neuroglia and endothelial cells

1973 • 96 citations

The Origin of Brain Macrophages in Traumatic Lesions, Wallerian Degeneration, and Retrograde Degeneration

1972 • 94 citations

Brain Cells in Culture: Morphological Transformation by a Protein

1974 • 92 citations

Subclass of astroglia in mouse cerebellum recognized by monoclonal antibody

1980 • 86 citations

Astrocyte cell lineage. III. The morphology of differentiating mouse astrocytes in colony culture

1984 • 76 citations

Responses to cortical injury: II. Widespread depression of the activity of an enzyme in cortex remote from a focal injury

1981 • 73 citations

Neuropeptides and astroglia in intracerebral hippocampal transplants: An immunohistochemical study in the rat

1984 • 73 citations

Distribution of glial fibrillary acidic protein and fibronectin in primary astroglial cultures from rat brain

1980 • 72 citations

Reinnervation of peripheral nerve segments implanted into the rat central nervous system

1980 • 70 citations

Differentiation of purified astrocytes in a chemically defined medium

1983 • 70 citations

Glial cell development in the rat optic nerve

1984 • 69 citations

Formation of a glial scar following microinjection of fetal neurons into the hippocampus or midbrain of the adult rat: An immunocytochemical study

1983 • 67 citations

Cell proliferation in injured spinal cord. An electron microscopic study

1973 • 67 citations

Effects of cultured astroglia on the survival of neonatal rat retinal ganglion cells in vitro

1984 • 66 citations

Distinction between nerve growth factor and glial factor

1975 • 66 citations

Developmentally regulated induction of neurite outgrowth from immature chick sensory neurons (DRG) by homogenates of avian or mammalian heart, liver and brain

1979 • 66 citations

Glial fibrillary acidic (GFA) protein in Müller glia. Immunofluorescence study of the goldfish retina

1984 • 65 citations

Human brain in tissue culture

1976 • 64 citations

Cultivation of immature astrocytes of mouse cerebellum in a serum-free, hormonally defined medium. Appearance of the mature astrocytic phenotype after addition of serum

1982 • 62 citations

Morphological studies on neuroglia

1981 • 62 citations

Trophic effects of brain areas on the developing cerebral cortex: I. Growth and histological organization of intraocular grafts

1983 • 60 citations

Isolation of a protein from bovine brain which promotes neurite extension from chick embryo cerebral cortex neurons in defined medium

1982 • 58 citations

Immunocytochemical demonstration of glial fibrillary acidic protein in mouse tanycytes

1981 • 55 citations

Astrocytic development in fetal parietal cortex grafted to cerebral and cerebellar cortex of immature rats

1983 • 50 citations

Cellular mechanisms for recovery from nervous system injury: A conference report☆

1981 • 49 citations

An autoradiographic study of DNA synthesis in adolescent and adult mouse forebrain

1974 • 49 citations

The distribution of types I, III, IV and V collagens in penetrant lesions of the central nervous system of the rat

1984 • 48 citations

Human brain in tissue culture. I. Acquisition, initial processing, and establishment of brain cell cultures

1975 • 47 citations

Astroglial proliferation and phenotype are modulated by neuronal plasma membrane

1984 • 47 citations

Spinal cord contains neurotrophic activity for spinal nerve sensory neurons. Late developmental appearance of a survival factor distinct from nerve growth factor

1984 • 47 citations

Cell division in injured spinal cord

1968 • 44 citations

Glial Disturbances in Isolated Neocortex: Evidence from Immunohistochemistry of Intraocular Grafts

1982 • 43 citations

Spinal cord grafts: An intraocular approach to enigmas of nerve growth regulation

1982 • 42 citations

Neuronotrophic activities in cerebrospinal fluid of head trauma patients

1984 • 40 citations

Reconstruction of brain circuitries by neural transplants

1979 • 40 citations

Human brain in tissue culture. IV. Morphological characteristics

1975 • 37 citations

Comparative study of astrocytes and mononuclear leukocytes reacting to brain trauma in mice

1973 • 36 citations

Glial cells from normal adult rat brain established in continuous culture

1978 • 36 citations

Autologous peripheral nerve grafting into murine brain as a model for studies of regeneration in the central nervous system

1983 • 35 citations

Glial fibrillary acidic protein-like immunoreactivity in the iris: development, distribution, and reactive changes following transplantation

1984 • 34 citations

Autologous sciatic nerve grafts to the rat spinal cord: Immunofluorescence studies with neurofilament and gliofilament (GFA) antisera

1980 • 33 citations

Nerve growth factors in chick tissues

1982 • 33 citations

Astrocytes and oligodendrocytes in dissociated cell culture of adult rat optic nerve

1980 • 32 citations

Reactive glial protein synthesis and early disappearance of saxitoxin binding in degenerating rat optic nerve

1983 • 29 citations

Preparation and partial characterization of highly purified primary cultures of neurons and non-neuronal (glial) cells from embryonic chick cerebral hemispheres and several other regions of the nervous system

1982 • 29 citations

An estimate of the number of cells arising by division in mouse cerebral hemispheres from age one to 12 months: An autoradiographic study of DNA synthesis

1975 • 28 citations

Anomalous migration of central nervous tissue to transplanted autonomic ganglia

1981 • 28 citations

Mitotic activity in adult rat brain induced by implantation of pieces of fetal rat brain and liver

1979 • 28 citations

Astrogliosis limits the integration of peripheral nerve grafts into the spinal cord

1983 • 27 citations

Glial antigens and the expression of neuroglial phenotypes

1982 • 25 citations

Cellular mechanisms in axonal growth

1979 • 21 citations

Influence of grafted glia cells and host mossy fibers on anomalously migrated host granule cells surviving in cortical transplants

1982 • 21 citations

Intracerebral transplantation of cultured neurons after reaggregation in a plasma clot

1987 • 21 citations

A study of glial cell proliferation in the molecular layer of the dentate gyrus of the rat following interruption of the ventral hippocampal commissure

1979 • 20 citations

Changes in expression of glial antigens M1 and C1 after cerebellar injury

1982 • 19 citations

Enhanced growth and morphological differentiation of isolated adult rat oligodendrocytes in vitro: use of a naturally produced extracellular matrix

1983 • 19 citations

Fibrous astrocytes and reactive astrocyte-like cells in transplants of cultured astrocyte precursor cells

1983 • 18 citations

Glial DNA synthesis and cell proliferation in the lesioned frontal cortex of the rat

1982 • 17 citations

Intracranial cerebellar grafts: Intermediate filament immunohistochemistry and electrophysiology

1984 • 17 citations

Inductive Factors in Gliosis.

1962 • 16 citations

Glial Cells in Huntington's Chorea

1984 • 11 citations

Effect of nerve section on perineuronal glial cells in the CNS of rat and cat

1984 • 10 citations

Localization of desmin in cultured astrocytes and its distribution in relation to glial fibrillary acidic (GFA) protein

1983 • 9 citations

Mitotic activity in the mouse brain after cortical and striatal lesions.

1983 • 8 citations

Derivation, characterization and purification of astroglial-cell cultures from adult brain, incorporating a new immunotoxin method for fibroblast elimination in vitro

1982 • 6 citations

Cell Surface Antigens in the Nervous System

1982 • 6 citations

Differentiation of glioblasts from adult brain

1983 • 6 citations

Growth regulator from spinal cord: produced in cultures of glial cells

1981 • 3 citations