High Affinity Not in the Vicinity?

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Neurotrophin signaling through the p75 neurotrophin receptor

2002 • 686 citations

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1999 • 452 citations

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

1994 • 397 citations

A Neurotrophin Signaling Cascade Coordinates Sympathetic Neuron Development through Differential Control of TrkA Trafficking and Retrograde Signaling

2004 • 381 citations

High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.

1994 • 313 citations

Structure of Nerve Growth Factor Complexed with the Shared Neurotrophin Receptor p75

2004 • 308 citations

Structural and Mechanistic Insights into Nerve Growth Factor Interactions with the TrkA and p75 Receptors

2007 • 295 citations

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF

1994 • 278 citations

Lysine 63 Polyubiquitination of the Nerve Growth Factor Receptor TrkA Directs Internalization and Signaling

2005 • 267 citations

An alternatively spliced form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin 3.

1994 • 204 citations

The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo

1999 • 122 citations

p75 neurotrophin receptor reduces ligand‐induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation

2005 • 94 citations

The Neurotrophin Receptor p75 Binds Neurotrophin-3 on Sympathetic Neurons with High Affinity and Specificity

1997 • 77 citations

Differential cross-regulation of TrkA and TrkC tyrosine kinase receptors with p75

2003 • 35 citations

Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells

2002 • 24 citations