Cross‐talk between B cell surface immunoglobulin and interleukin 4 receptors: the role of protein kinase C and Ca²⁺‐mediated signals

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

B-Cell Stimulatory Factor-1/Interleukin 4

1987 • 602 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

Down-regulation of protein kinase C is due to an increased rate of degradation

1987 • 442 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

The mechanism of protein kinase C activation

1989 • 423 citations

B lymphocyte receptors and polyphosphoinositide degradation

1985 • 332 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

Molecular Mechanisms of Transmembrane Signaling in B Lymphocytes

1987 • 279 citations

B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes.

1987 • 251 citations

Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.

1981 • 144 citations

Interleukin 4 activates human B lymphocytes via transient inositol lipid hydrolysis and delayed cyclic adenosine monophosphate generation

1990 • 113 citations

Activation and proliferation signals in mouse B cells VIII. Induction of DNA synthesis in B cells by a combination of calcium ionophores and phorbol myristate acetate

1986 • 104 citations

Induction of resting B cells to DNA synthesis by soluble monoclonal anti‐immunoglobulin

1984 • 103 citations

Activation of human B cells. Comparison of the signal transduced by IL-4 to four different competence signals.

1989 • 90 citations

G protein coupling of antigen receptor-stimulated polyphosphoinositide hydrolysis in B cells.

1988 • 89 citations

Identification of interleukin 4 receptor‐associated proteins and expression of both high‐ and low‐affinity binding on human lymphoid cells

1989 • 75 citations

BSF-1 action on resting B cells does not require elevation of inositol phospholipid metabolism or increased [Ca2+]i.

1986 • 74 citations

BSF1 induces membrane protein phosphorylation but not phosphoinositide metabolism, Ca2+ mobilization, protein kinase C translocation, or membrane depolarization in resting murine B lymphocytes.

1986 • 70 citations

Interleukin 4 and soluble CD23 as progression factors for human B lymphocytes: analysis of their interactions with agonists of the phosphoinositide “dual pathway” of signalling

1988 • 68 citations

Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells.

1986 • 58 citations

B-lymphocyte activation mediated by anti-immunoglobulin antibody in the absence of protein kinase C.

1987 • 54 citations

Activation and proliferation signals in mouse B cells I. A comparison of the capacity of anti‐Ig antibodies or phorbol myristic acetate to activate B cells from CBA/N or normal mice into G₁

1984 • 52 citations

Increased expression of surface IgM but not IgD or IgG on human B cells in response to IL-4.

1989 • 50 citations

CYCLOSPORINE-SENSITIVE AND CYCLOSPORINE-INSENSITIVE MODES OF B CELL STIMULATION

1988 • 48 citations

B-cell-stimulatory factor 1 reverses Fc receptor-mediated inhibition of B-lymphocyte activation.

1987 • 43 citations

IL-4 induces loss of B lymphocyte Fc gamma R II ligand binding capacity.

1988 • 29 citations

Effects of cyclosporine on responses of murine B cells to T cell-derived lymphokines.

1986 • 28 citations

Tumor-promoting phorbol esters suppress receptor-stimulated inositol phospholipid degradation and Ca2+ mobilization in mouse lymphocytes

1987 • 24 citations

Expression of B cell surface receptors. II. IL-4 can accelerate the developmental expression of the murine B cell IgE Fc receptor.

1989 • 23 citations

Purification of monoclonal antibodies from ascites using ABx liquid chromatography column

1987 • 22 citations

Differential regulation of murine B cell Fc gamma RII expression by CD4+ T helper subsets.

1989 • 19 citations

Protein kinase C activators inhibit the antigen receptor‐coupled polyphosphoinositide phosphodiesterase in murine B lymphocytes

1988 • 12 citations