Hunting for the pore of voltage-gated channels

Mechanism of ion permeation through calcium channels

1984 • 850 citations

Calcium channel characteristics conferred on the sodium channel by single mutations

1992 • 776 citations

Non‐selective conductance in calcium channels of frog muscle: calcium selectivity in a single‐file pore.

1984 • 643 citations

Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K ⁺ Channel

1991 • 634 citations

Mutations Affecting Tea Blockade and Ion Permeation in Voltage-activated K ⁺ Channels

1990 • 569 citations

Molecular model of the action potential sodium channel.

1986 • 525 citations

Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II

1991 • 460 citations

The aromatic binding site for tetraethylammonium ion on potassium channels

1992 • 446 citations

Alteration of ionic selectivity of a K+ channel by mutation of the H5 region

1991 • 445 citations

A Mutant of TTX-Resistant Cardiac Sodium Channels with TTX-Sensitive Properties

1992 • 387 citations

Exchange of Conduction Pathways Between Two Related K ⁺ Channels

1991 • 387 citations

Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor

1989 • 351 citations

A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II

1989 • 336 citations

Molecular Localization of an Ion-Binding Site Within the Pore of Mammalian Sodium Channels

1992 • 281 citations

Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor

1990 • 220 citations

Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethylammonium

1992 • 142 citations

Batrachotoxin-modified sodium channels in planar lipid bilayers. Ion permeation and block.

1987 • 133 citations

Differences between the deep pores of K+ channels determined by an interacting pair of nonpolar amino acids

1992 • 104 citations

A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity

1992 • 71 citations

Competitive binding interaction between Zn2+ and saxitoxin in cardiac Na+ channels. Evidence for a sulfhydryl group in the Zn2+/saxitoxin binding site

1991 • 60 citations

Zn2(+)-induced subconductance events in cardiac Na+ channels prolonged by batrachotoxin. Current-voltage behavior and single-channel kinetics.

1991 • 41 citations

Chapter 16 Sodium Channels in Lipid Bilayers: Have We Learned Anything Yet?

1988 • 4 citations