Thegastrulation defectivegene ofDrosophila melanogasteris a member of the serine protease superfamily

Basic local alignment search tool

1990 • 87,358 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 • 1,560 citations

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

1988 • 1,077 citations

Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster

1983 • 626 citations

[2] Families of serine peptidases

1994 • 621 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology.

1991 • 504 citations

Vectors for P-Mediated Transformation in Drosophila

1988 • 399 citations

Comparative modeling methods: Application to the family of the mammalian serine proteases

1990 • 383 citations

SIGNALING PATHWAYS THAT ESTABLISH THE DORSAL-VENTRAL PATTERN OF THE DROSOPHILA EMBRYO

1995 • 348 citations

The molecular organization of the Antennapedia locus of drosophila

1983 • 331 citations

A restriction map of the bacteriophage T4 genome

1980 • 326 citations

The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo

1994 • 321 citations

The polarity of the dorsoventral axis in the drosophila embryo is defined by an extracellular signal

1991 • 260 citations

cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo.

1989 • 246 citations

Gametogenesis and the early embryo

1987 • 207 citations

Intercellular signaling and the polarization of body axes during Drosophila oogenesis.

1996 • 202 citations

The role of easter, an apparent serine protease, in organizing the dorsal-ventral pattern of the Drosophila embryo

1989 • 175 citations

Vectors: a survey of molecular cloning vectors and their uses.

1988 • 173 citations

A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo

1994 • 161 citations

A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease

1986 • 148 citations

Complete primary structure for the zymogen of human complement factor B.

1984 • 142 citations

Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal–ventral pattern formation

1991 • 140 citations

Dorsal midline fate in Drosophila embryos requires twisted gastrulation, a gene encoding a secreted protein related to human connective tissue growth factor.

1994 • 139 citations

The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundas: cloning and expression

1991 • 118 citations

Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity

1992 • 112 citations

An unusual mosaic protein with a protease domain, encoded by the nudeI gene, is involved in defining embryonic dorsoventral polarity in Drosophila

1995 • 109 citations

Activation of the easter zymogen is regulated by five other genes to define dorsal-ventral polarity in the Drosophila embryo

1992 • 84 citations

SALIVARY CHROMOSOME BANDS AND THE FREQUENCY OF CROSSING OVER IN DROSOPHILA MELANOGASTER

1971 • 82 citations

Behavioral and Cytogenetic Analysis of the cacophony Courtship Song Mutant and Interacting Genetic Variants in Drosophila melanogaster

1987 • 78 citations

Ventralizing signal determined by protease activation in Drosophila embryogenesis

1994 • 76 citations

windbeutel,a gene required for dorsoventral patterning inDrosophila,encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum

1998 • 67 citations

Extracellular proteases and embryonic pattern formation

1992 • 62 citations

Crystal structure analysis and refinement of two variants of trigonal trypsinogen

1978 • 53 citations

Mouse 7S nerve growth factor: complete sequence of a cDNA coding for the .alpha.-subunit precursor and its relationship to serine proteases

1984 • 51 citations

Cell-cell signaling, microtubules, and the loss of symmetry in the drosophila oocyte

1995 • 46 citations

Mutational analysis of the Drosophila snake protease: an essential role for domains within the proenzyme polypeptide chain.

1994 • 45 citations

Developmental genetics of the gastrulation defective locus in Drosophila melanogaster

1988 • 32 citations

Structural analysis of chicken factor B-like protease and comparison with mammalian complement proteins factor B and C2.

1993 • 26 citations

Multiple signaling pathways establish both the individuation and the polarity of the oocyte follicle inDrosophila

1996 • 19 citations

Injection of wild-type cytoplasm and poly(A)+ RNA provokes phenotype rescue in sp�tzle mutant Drosophila embryos

1987 • 9 citations