Chronic Alcohol Ingestion: Nerve Growth Factor Gene Expression and Neurotrophic Activity in Rat Hippocampus

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain.

1990 • 993 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

The changing scene of neurotrophic factors

1991 • 827 citations

Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's disease

1983 • 811 citations

The nerve growth factor: thirty-five years later.

1987 • 720 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture

1990 • 684 citations

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3

1991 • 530 citations

Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons

1990 • 529 citations

Studies on the expression of the beta nerve growth factor (NGF) gene in the central nervous system: level and regional distribution of NGF mRNA suggest that NGF functions as a trophic factor for several distinct populations of neurons.

1986 • 528 citations

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system.

1986 • 525 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

New protein fold revealed by a 2.3-Å resolution crystal structure of nerve growth factor

1991 • 500 citations

Nerve Growth Factor Gene Expression in the Developing Rat Brain

1986 • 436 citations

Neuronal Loss in Hippocampus Induced by Prolonged Ethanol Consumption in Rats

1980 • 396 citations

Function and evolution in the NGF family and its receptors

1992 • 338 citations

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

1992 • 336 citations

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

1986 • 335 citations

Morphological response of axotomized septal neurons to nerve growth factor

1988 • 323 citations

Rat β‐nerve growth factor sequence and site of synthesis in the adult hippocampus

1988 • 309 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system

1987 • 268 citations

Neuroanatomical and Functional Deficits Subsequent to Chronic Ethanol Administration in Animals

1981 • 246 citations

Delayed treatment with nerve growth factor reverses the apparent loss of cholinergic neurons after acute brain damage

1988 • 233 citations

Association of 125I-nerve growth factor with PC12 pheochromocytoma cells. Evidence for internalization via high-affinity receptors only and for long-term regulation by nerve growth factor of both high- and low-affinity receptors.

1984 • 197 citations

Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): Distribution, morphology, and colocalization with cholinergic enzymes

1988 • 176 citations

Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol

1988 • 173 citations

Impairment of shuttle box avoidance learning following prolonged alcohol consumption in rats

1971 • 147 citations

Developmental regulation of nerve growth factor and its receptor in the rat caudate-putamen

1989 • 126 citations

Messenger RNAs for trk and the low-affinity NGF receptor in rat basal forebrain

1991 • 107 citations

Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons

1993 • 79 citations

Effect of Chronic Ethanol on the Septohippocampal System: A Role for Neurotrophic Factors?

1993 • 49 citations

Changes in cholinergic activity in human hippocampus following chronic alcohol abuse

1983 • 48 citations

Continuous presence of nerve growth factor is required for maintenance of cholinergic septal neurons in organotypic slice cultures

1990 • 43 citations

Chronic ethanol consumption reduces the neurotrophic activity in rat hippocampus

1992 • 34 citations

Chronic treatment with scopolamine and physostigmine changes nerve growth factor (NGF) receptor density and NGF content in rat brain

1991 • 27 citations

Signal transduction and regulation of neurotrophins

1992 • 26 citations

Neither chronic exposure to ethanol nor aging affects type I or type II corticosteroid receptors in rat hippocampus

1989 • 22 citations

Sequestration requirements for the degradation of ¹²⁵I‐labeled β nerve growth factor bound to embryonic sensory neurons

1982 • 14 citations

Differential regulation of the nerve growth factor and brain‐derived neurotrophic factor genes in L929 mouse fibroblasts

1992 • 13 citations