Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Novel Proteinaceous Infectious Particles Cause Scrapie

1982 • 4,972 citations

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

1993 • 2,237 citations

Molecular Biology of Prion Diseases

1991 • 1,978 citations

A cellular gene encodes scrapie PrP 27-30 protein

1985 • 1,494 citations

Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome

1989 • 834 citations

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

1986 • 829 citations

Does the Agent of Scrapie Replicate without Nucleic Acid ?

1967 • 671 citations

CREUTZFELDT-JAKOB DISEASE VIRUS ISOLATIONS FROM THE GERSTMANN-STRÄUSSLER SYNDROME

1981 • 534 citations

Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein

1990 • 531 citations

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

1985 • 490 citations

Regional mapping of prion proteins in brain.

1992 • 329 citations

Pathology of Kuru.

1959 • 284 citations

Rapid detection of Creutzfeldt‐Jakob disease and scrapie prion proteins

1990 • 217 citations

Amyloid Filaments in Inclusion Body Myositis

1991 • 205 citations

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

1992 • 204 citations

Fatal familial insomnia

1992 • 200 citations

Creutzfeldt–Jakob Disease Prion Proteins in Human Brains

1985 • 197 citations

Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.

1991 • 195 citations

Amyloid plaques in Creutzfeldt‐Jakob disease stain with prion protein antibodies

1986 • 175 citations

INHERITED PRION DISEASE WITH 144 BASE PAIR GENE INSERTION: 1. GENEALOGICAL AND MOLECULAR STUDIES

1992 • 168 citations

Diagnosis of Creutzfeldt-Jakob Disease by Western Blot Identification of Marker Protein in Human Brain Tissue

1986 • 154 citations

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.

1994 • 154 citations

Viroids and prions.

1982 • 145 citations

Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

1992 • 131 citations

Analysis of the prion protein gene in thalamic dementia

1992 • 99 citations

Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD).

1993 • 97 citations

Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids

1987 • 89 citations

Immunoblotting of Creutzfeldt‐Jakob disease prion proteins: Host species—specific epitopes

1987 • 81 citations

CNS amyloid proteins in neurodegenerative diseases

1988 • 81 citations

The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease.

1992 • 80 citations

Familial Neurological Disease Associated With Spongiform Encephalopathy

1976 • 74 citations

Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob Disease

1994 • 61 citations

Atypical Creutzfeldt‐Jakob disease in an American family with an insert mutation in the PRNP amyloid precursor gene

1992 • 58 citations

Neuronal Enzymatic Failure in Creutzfeldt-Jakob Disease

1964 • 46 citations

Small virus-like structure in fractions from scrapie hamster brain

1994 • 39 citations

Scrapie agent reflication without the prion protein?

1993 • 18 citations