Scrapie agent reflication without the prion protein?

Novel Proteinaceous Infectious Particles Cause Scrapie

1982 • 4,972 citations

Mice devoid of PrP are resistant to scrapie

1993 • 2,058 citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

A cellular gene encodes scrapie PrP 27-30 protein

1985 • 1,494 citations

Identification of a Protein That Purifies with the Scrapie Prion

1982 • 1,260 citations

Nature of the Scrapie Agent: Self-replication and Scrapie

1967 • 1,128 citations

A protease-resistant protein is a structural component of the Scrapie prion

1983 • 919 citations

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive.

1991 • 627 citations

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.

1990 • 510 citations

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

1985 • 490 citations

Abnormal fibrils from scrapie-infected brain

1981 • 473 citations

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

1991 • 412 citations

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

1993 • 391 citations

Scrapie infectivity, fibrils and low molecular weight protein

1983 • 345 citations

Potent Inhibition of Scrapie‐Associated PrP Accumulation by Congo Red

1992 • 228 citations

Scrapie Strain Variation and Its Implications

1991 • 143 citations

Congo red inhibition of scrapie agent replication

1993 • 128 citations

Host Genetic Control of Spontaneous and Induced Immunity to Friend Murine Retrovirus Infection

1990 • 126 citations