Macrophages, oxidised lipids and atherosclerosis

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

1976 • 606 citations

A macrophage-dependent factor that stimulates the proliferation of fibroblasts in vitro.

1976 • 579 citations

Studies on the pathogenesis of atherosclerosis. I. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats.

1983 • 487 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

Phagocyte-generated oxygen metabolites and cellular injury.

1982 • 457 citations

Oxygen-Dependent Microbial Killing by Phagocytes

1978 • 448 citations

Dietary induced atherogenesis in swine. Morphology of the intima in prelesion stages.

1979 • 393 citations

STUDIES ON THE ROLE OF LIPOPEROXIDES IN HUMAN PATHOLOGY

1952 • 347 citations

Lipid oxidation: Biologic effects and antioxidants—A review

1980 • 308 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. IV. Investigation of macrophage-like properties of aortic cell populations.

1979 • 297 citations

Specificity of receptor-mediated recognition of malondialdehyde-modified low density lipoproteins.

1982 • 279 citations

Changes in the endothelium of the aorta and the behaviour of macrophages in experimental atheroma of rabbits

1958 • 270 citations

Lipid peroxidation: its measurement, occurrence, and significance in animal tissues.

1967 • 250 citations

Individual Variation in the Effects of Dietary Cholesterol on Plasma Lipoproteins and Cellular Cholesterol Homeostasis in Man

1981 • 241 citations

Monocytic origin of foam cells in human atherosclerotic plaques

1984 • 202 citations

Angiotoxicity of Oxygenated Sterols and Possible Precursors

1980 • 202 citations

Lipid Peroxidation by Human Blood Phagocytes

1974 • 177 citations

Angiotoxicity and arteriosclerosis due to contaminants of USP-grade cholesterol.

1976 • 176 citations

Fine structure of human aortic intimal thickening and fatty streaks.

1965 • 168 citations

Haematological Cytochemistry

1981 • 154 citations

"Ceroid" Pigment in Human Tissues.

1946 • 132 citations

Electron microscopic study of experimental atherosclerosis in the rat.

1962 • 132 citations

Lipids of human atheroma Part 4. Characterisation of a new group of polar sterol esters from human atherosclerotic plaques

1971 • 113 citations

The aortic tunica intima in young and aging rats

1972 • 100 citations

The genesis of atherosclerosis

1941 • 95 citations

Connective tissue responses to oxysterols

1982 • 85 citations

Insoluble lipids in human atherosclerotic plaques

1982 • 82 citations

Sterol metabolism

1970 • 72 citations

INCREASED LEUCOCYTE OXIDATIVE METABOLISM IN HYPERLIPOPROTEINAEMIA

1982 • 68 citations

The role of smooth muscle cells and hematogenous macrophages in atheroma

1977 • 62 citations

The origin of foam cells in atherosclerosis.

1971 • 57 citations

On the cellular origin and development of atheromatous plaques

1983 • 56 citations

Narrow superficial injury to rabbit aortic endothelium

1982 • 56 citations

The pathogenesis of cholesterol arteriosclerosis in the rabbit

1953 • 54 citations

Detection of macrophages in atherosclerotic lesions with cytochrome oxidase.

1976 • 51 citations

Effects of peripheral blood monocytes on human vascular cell proliferation

1981 • 50 citations

Transformation of monocytes into "fat" cells.

1978 • 49 citations

The Incidence of Acid-Fast Pigment (Ceroid) in Aortic Atherosclerosis

1952 • 46 citations

The cytochemical demonstration of lipids in blood and bone‐marrow cells

1953 • 44 citations

Prostacyclin and atherosclerosis

1979 • 39 citations

Accumulation of lipids in the leukocytes of rats fed atherogenic diets

1964 • 33 citations

Circulating lipophages, serum lipids, and atherosclerosis in rats.

1967 • 31 citations

THE FINE STRUCTURE OF CEROID IN HUMAN ATHEROMA

1967 • 30 citations

The circulating lipophage and experimental atherosclerosis

1961 • 29 citations

The lipophage in hyperlipemic rats: An electron microscopic study

1966 • 29 citations

The adhesion of different cell types to cultured vascular endothelium: effects of culture density and age.

1984 • 28 citations

The occurrence of iron and ceroid in coronary arteries

1956 • 27 citations

The Release of Hydrogen Peroxide from Mononuclear Phagocytes and its Role in Extracellular Cytolysis

1980 • 25 citations

Sterol metabolism

1973 • 25 citations

Coronary intimal necrosis occurring as an early stage of atherosclerotic involvement

1981 • 23 citations

The binding of total low density lipoproteins in human arterial intima affected and unaffected by atherosclerosis

1979 • 21 citations

On the Role of Fatty Acid Peroxides in Atherogenesis

1965 • 21 citations

Peroxides as a factor of atherosclerosis.

1965 • 20 citations

Tissue reaction to atheroma lipids

1973 • 18 citations

Crystalline ester cholesterol and atherosclerosis.

1949 • 17 citations

The production of ceroid by mouse peritoneal macrophages in vitro.

1984 • 17 citations

Composition and metabolism of lipid in macrophages from normally fed and cholesterol-fed rabbits

1978 • 16 citations

OXIDATION OF ¹⁴C‐LABELLED CHYLOMICRON FAT AND ¹⁴C‐LABELLED UNESTERIFIED FATTY ACIDS BY MACROPHAGES IN VITRO AND THE EFFECT OF CLEARING FACTOR

1960 • 15 citations

The microdissection of large atherosclerotic plaques to give morphologically and topographically defined fractions for analysis *1Part 2. Studies on “nile blue” cells

1972 • 15 citations

Peroxides as a factor of atherosclerosis

1966 • 14 citations

Intimal Lesions in Arteries of Vit. E Deficient Rats.

1960 • 12 citations

A COMPARISON OF THE OXIDATION OF CHOLESTEROL‐26‐¹⁴C, PALMITATE‐1‐¹⁴C AND TRIPALMITIN‐1‐¹⁴C BY MACROPHAGES IN VITRO

1961 • 9 citations

Leukocyte Lipids of Human Blood

1967 • 9 citations

Tocopherol, Non-protein SH and Metals in the Human Aorta

1969 • 6 citations

Insoluble Hard Material found in Human Atherosclerotic Aortas

1968 • 6 citations

The influence of dietary fats on lipid synthesis by human mononuclear cells

1981 • 5 citations

Studies on the distribution and chemical properties of the bound lipids of the human aorta

1966 • 4 citations