A folding model of α-lactalbumin deduced from the three-state denaturation mechanism

Methods in Enzymology , Vol

1966 • 26,261 citations

Tissue sulfhydryl groups

1959 • 25,130 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Prediction of protein conformation

1974 • 3,327 citations

Protein Denaturation

1968 • 2,108 citations

Protein denaturation. C. Theoretical models for the mechanism of denaturation.

1970 • 1,550 citations

Structure and stability of biological macromolecules

1969 • 1,313 citations

Protein Denaturation

1970 • 1,264 citations

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

1975 • 1,108 citations

A simplified representation of protein conformations for rapid simulation of protein folding

1976 • 1,099 citations

Experimental and Theoretical Aspects of Protein Folding

1975 • 965 citations

A possible three-dimensional structure of bovine α-lactalbumin based on that of hen's egg-white lysozyme

1969 • 517 citations

The Complete Amino Acid Sequence of Bovine α-Lactalbumin

1970 • 327 citations

Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. I. Dependence on pH at 25°

1969 • 275 citations

Intermediates in Protein Folding Reactions and the Mechanism of Protein Folding

1975 • 257 citations

Three-state denaturation of α-lactalbumin by guanidine hydrochloride

1976 • 249 citations

Computation of structures of homologous proteins. .alpha.-Lactalbumin from lysozyme

1974 • 230 citations

Hydrophobic Interactions

1967 • 217 citations

A model of myoglobin self-organization

1975 • 207 citations

Thermodynamic investigations of proteins

1976 • 203 citations

A quantitative treatment of the kinetics of the folding transition of ribonuclease A

1976 • 167 citations

Stability of the polyglutamic acid .alpha. helix

1968 • 158 citations

The Thermodynamic Basis of the Stability of Proteins, Nucleic Acids, and Membranes

1976 • 152 citations

Conformational studies of poly‐<scp>L</scp>‐alanine in water

1968 • 149 citations

Experimental Free Energy and Enthalpy of Formation of the α Helix¹

1966 • 146 citations

Equilibrium and kinetics of the unfolding of lysozyme (muramidase) by guanidine hydrochloride

1966 • 141 citations

Thermodynamic investigations of proteins

1976 • 137 citations

Direct Spectrophotometric Measurement of the Rate of Reduction of Disulfide Bonds

1973 • 134 citations

Induced dynamic nuclear spin polarization in reactions of photochemically and thermally generated triplet diphenylmethylene

1969 • 119 citations

The mechanism of folding of globular proteins. Equilibria and kinetics of conformational transitions of penicillinase from Staphylococcus aureus involving a state of intermediate conformation

1976 • 108 citations

Hydrogen ion titration curve of lysozyme in 6 M guanidine hydrochloride

1971 • 98 citations

The Disulfide Bonds of Bovine α-Lactalbumin

1970 • 98 citations

Inter- and Intramolecular Interactions of α-Lactalbumin. II. Aggregation Reactions at Acid pH^*

1964 • 94 citations

Thermodynamics of the denaturation of ribonuclease by guanidine hydrochloride

1970 • 93 citations

On the rate‐determining step for helix propagation in the helix–coil transition of polypeptides in solution

1975 • 76 citations

A theory of protein molecule self-organization

1976 • 75 citations

Thermodynamics of the denaturation of lysozyme by guanidine hydrochloride. III. Dependence on temperature

1970 • 69 citations

The heat-unfolded state of ribonuclease A is an equilibrium mixture of fast and slow refolding species

1975 • 67 citations

Folding and stability of helical proteins: Carp myogen

1976 • 63 citations

Inter- and Intramolecular Interactions of α-Lactalbumin

1971 • 59 citations

The Stability of the Helical Conformation of Random L-Leucine-L-Glutamic Acid Copolymers in Aqueous Solution¹

1965 • 55 citations

Equilibrium and kinetics of the unfolding of α-lactalbumin by guanidine hydrochloride

1973 • 51 citations

Circular dichroism spectra of α-lactalbumin

1970 • 48 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. IX. Glutamic Acid Parameters from Random Poly(hydroxybutylglutamine-co-L-glutamic acid)

1975 • 47 citations

Kinetics of thermal unfolding of lysozyme

1973 • 42 citations

Prediction of structural homology between bovine α-lactalbumin and hen egg white lysozyme

1971 • 42 citations

Helix–coil transition kinetics in aqueous poly(α,<scp>L</scp>‐glutamic acid)

1975 • 41 citations

A comparison of the denatured states of α-lactalbumin and lysozyme

1974 • 32 citations

Equilibrium and kinetics of the unfolding of α-lactalbumin by guanidine hydrochloride (II)

1976 • 27 citations

Change in the Ultraviolet Absorption of an Adenosine Triphosphate Analog, β-Naphthyl Triphosphate, during Its Hydrolysis by Heavy Meromyosin1

1975 • 26 citations

Inter- and intramolecular interactions of α-lactalbumin

1972 • 26 citations

Calorimetric Determination of Denaturation Enthalpy for Lysozyme in Guanidine Hydrochloride

1971 • 24 citations

Equilibrium and kinetics of the unfolding of α-lactalbumin by guanidine hydrochloride (IV) Dependence of the N ⇌ A transconformation on temperature

1977 • 21 citations

Thermodynamics of the unfolding of α-lactalbumin by guanidine thiocyanate

1974 • 13 citations

Calorimetric Study on the Conformational Transition of α-Lactalbumin Induced by Guanidine Hydrochloride

1977 • 11 citations