A Widespread and Early Requirement for a Novel Notch Function during Drosophila Embryogenesis

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

The development of Drosophila melanogaster

1994 • 3,057 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1991 • 1,693 citations

Nuclear Access and Action of Notch In Vivo

1998 • 730 citations

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1998 • 720 citations

Chapter 24 Imaging Neuronal Subsets and Other Cell Types in Whole-Mount Drosophila Embryos and Larvae Using Antibody Probes

1994 • 608 citations

Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.

1995 • 594 citations

The suppressor of hairless protein participates in notch receptor signaling

1994 • 547 citations

LIN-12/Notch signaling: lessons from worms and flies

1998 • 545 citations

The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development

1991 • 501 citations

On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

1983 • 493 citations

Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila.

1992 • 484 citations

Intrinsic activity of the lin-12 and Notch intracellular domains in vivo

1993 • 466 citations

The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

1995 • 430 citations

Numb Antagonizes Notch Signaling to Specify Sibling Neuron Cell Fates

1996 • 415 citations

The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate

1997 • 407 citations

Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein

1985 • 406 citations

Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system

1992 • 397 citations

Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing

1995 • 392 citations

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

1996 • 372 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

Expression and Function of the Segmentation Gene fushi tarazu During Drosophila Neurogenesis

1988 • 342 citations

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila

1996 • 331 citations

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.

1996 • 316 citations

Autosomal P[ovo D1 ] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras

1993 • 302 citations

Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates

1992 • 264 citations

A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing

1996 • 260 citations

The function of the neurogenic genes during epithelial development in the Drosophila embryo

1992 • 248 citations

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

1992 • 246 citations

A role for the Drosophila neurogenic genes in mesoderm differentiation

1991 • 235 citations

Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo

1992 • 211 citations

New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system

1995 • 206 citations

The Notch locus of Drosophila melanogaster

1983 • 203 citations

Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS

1998 • 199 citations

Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos

1998 • 193 citations

The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs

1991 • 179 citations

Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development

1996 • 175 citations

Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster

1987 • 119 citations

tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the drosophila PNS

1995 • 110 citations

The expression and role of a proneural gene, achaete, in the development of the larval nervous system of Drosophila.

1993 • 103 citations

A dual requirement for neurogenic genes in Drosophila myogenesis

1993 • 95 citations

A Functional Analysis of Notch Mutations in Drosophila

1997 • 91 citations

Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification

1995 • 85 citations

The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene

1994 • 71 citations

Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila

1999 • 59 citations

The Drosophila neurogenic gene big brain, which encodes a membrane-associated protein, acts cell autonomously and can act synergistically with Notch and Delta

1997 • 59 citations

huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding

1995 • 58 citations

Hox genes differentially regulate Serrate to generate segment-specific structures

1999 • 54 citations

Evidence for a novel Notch pathway required for muscle precursor selection in Drosophila

1998 • 48 citations

The engrailed locus of D. melanogaster provides an essential zygotic function in precellular embryos

1985 • 46 citations

Cytogenetic definition and morphogenetic analysis of Delta, a gene affecting neurogenesis in Drosophila melanogaster.

1988 • 38 citations

Mastermind Acts Downstream of Notch to Specify Neuronal Cell Fates in theDrosophilaCentral Nervous System

1999 • 36 citations

Function of trans-acting genes of theachaete-scute complex in sensory organ patterning in the mesonotum ofDrosophila

1991 • 29 citations