Positive Selection by Purified MHC Class II / Thymic Epithelial CellsIn Vitro: Costimulatory Signals Mediated by B7 Are Not Involved

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.

1992 • 558 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

1993 • 359 citations

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.

1991 • 349 citations

Activation events during thymic selection.

1992 • 326 citations

Studies on T cell maturation on defined thymic stromal cell populations in vitro.

1992 • 249 citations

Molecules involved in T-cell costimulation

1993 • 237 citations

Costimulation of T-cell growth

1992 • 225 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Successful transplantation across major histocompatibility barrier of deoxyguanosine-treated embryonic thymus expressing class II antigens

1984 • 138 citations

Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction

1993 • 138 citations

Intrathymic presentation of circulating non-major histocompatibility complex antigens

1984 • 102 citations

A cell line that can induce thymocyte positive selection

1992 • 91 citations

Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes.

1992 • 90 citations

CD28-B7 interactions are not required for intrathymic clonal deletion

1993 • 53 citations