Association of VEGF genetic polymorphisms with prostate carcinoma risk and clinical outcome

A simple salting out procedure for extracting DNA from human nucleated cells

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A New Statistical Method for Haplotype Reconstruction from Population Data

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Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

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Cancer Statistics, 2005

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Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Cancer Statistics, 2004

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Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland

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Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

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Vascular endothelial growth factor (VEGF) and its receptors

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Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Molecular and biological properties of vascular endothelial growth factor

1999 • 1,174 citations

Detection of Organ-Confined Prostate Cancer Is Increased Through Prostate-Specific Antigen—Based Screening

1993 • 1,014 citations

Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages In Vivo

1998 • 933 citations

Intratumor microvessel density as a prognostic factor in cancer.

1995 • 881 citations

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

2003 • 858 citations

Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages In Vivo

1998 • 828 citations

Regulation of angiogenesis via vascular endothelial growth factor receptors.

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How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture.

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IDENTIFICATION OF POLYMORPHISMS WITHIN THE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENE: CORRELATION WITH VARIATION IN VEGF PROTEIN PRODUCTION

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Hereditary Prostate Cancer: Epidemiologic and Clinical Features

1993 • 610 citations

A Common Polymorphism in the 5′-Untranslated Region of the VEGF Gene Is Associated With Diabetic Retinopathy in Type 2 Diabetes

2002 • 554 citations

A Common 936 C/T Mutation in the Gene for Vascular Endothelial Growth Factor Is Associated with Vascular Endothelial Growth Factor Plasma Levels

2000 • 545 citations

Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells.

1998 • 524 citations

VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression

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Vascular permeability factor/vascular endothelial growth factor:A multifunctional angiogenic cytokine

1997 • 474 citations

Assignment of the Vascular Endothelial Growth Factor Gene to Human Chromosome 6p21.3

1996 • 473 citations

Vascular Endothelial Growth Factor Affects Dendritic Cell Maturation Through the Inhibition of Nuclear Factor-κB Activation in Hemopoietic Progenitor Cells

1998 • 440 citations

Decreased antigen presentation by dendritic cells in patients with breast cancer.

1997 • 439 citations

Vascular Endothelial Growth Factor Gene Polymorphisms Are Associated with Acute Renal Allograft Rejection

2002 • 413 citations

Haplotype analysis of the polymorphic human vascular endothelial growth factor gene promoter.

2003 • 370 citations

VEGF as a Mediator of Tumor-Associated Immunodeficiency

2001 • 351 citations

Influence of cytokine gene polymorphisms on the development of prostate cancer.

2002 • 342 citations

A common 936 C/T gene polymorphism of vascular endothelial growth factor is associated with decreased breast cancer risk

2003 • 322 citations

Prognostic Value of Vascular Endothelial Growth Factor in Breast Cancer

2000 • 302 citations

Novel polymorphisms in the promoter and 5′ UTR regions of the human vascular endothelial growth factor gene

1999 • 301 citations

Angiogenesis and Metastasis

2002 • 294 citations

Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening

1993 • 278 citations

Cancer Risk and Low-Penetrance Susceptibility Genes in Gene-Environment Interactions

2000 • 275 citations

VEGF gene sequence variation defines VEGF gene expression status and angiogenic activity in non-small cell lung cancer

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Plasma levels of vascular endothelial growth factor are increased in patients with metastatic prostate cancer

1999 • 251 citations

Angiogenesis and Prostate Cancer: In vivo and In vitro Expression of Angiogenesis Factors by Prostate Cancer Cells

1998 • 251 citations

Vascular Endothelial Growth Factor Polymorphisms in Relation to Breast Cancer Development and Prognosis

2005 • 246 citations

Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function.

1999 • 235 citations

Differential Roles of Vascular Endothelial Growth Factor Receptors 1 and 2 in Dendritic Cell Differentiation

2005 • 231 citations

Expression of vascular endothelial growth factor receptors in human prostate cancer

1999 • 202 citations

A potential autocrine role for vascular endothelial growth factor in prostate cancer.

2002 • 178 citations

Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma

2002 • 162 citations

Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study.

2001 • 158 citations

Cytokine gene polymorphisms and breast cancer susceptibility and prognosis*

2004 • 157 citations

Association of Genetic Polymorphisms in the VEGF Gene with Breast Cancer Survival

2005 • 151 citations

Vascular Endothelial Growth Factor Gene Polymorphisms and Risk of Primary Lung Cancer

2005 • 136 citations

Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes

2005 • 134 citations

Vascular endothelial growth factor expression and capillary architecture in high-grade PIN and prostate cancer in untreated and androgen-ablated patients

2000 • 119 citations

Vascular endothelial growth factor effects on nuclear factor-kappaB activation in hematopoietic progenitor cells.

2001 • 55 citations

An autocrine loop for vascular endothelial growth factor is established in prostate cancer cells generated after prolonged treatment with interleukin 6

2004 • 52 citations

Vascular endothelial growth factor expression, S-phase fraction and thymidylate synthase quantitation in node-positive colon cancer: Relationships with tumor recurrence and resistance to adjuvant chemotherapy

2001 • 49 citations

Single Nucleotide Polymorphisms in the 3' Untranslated Region of Vascular Endothelial Growth Factor Gene in Japanese Population with or without Renal Cell Carcinoma.

2002 • 48 citations

Expression of Vascular Endothelial Growth Factor Gene and Its Receptor (flt-1) Gene in Urinary Bladder Cancer.

1998 • 41 citations