DDAVP IS NOT A PANACEA FOR CHILDREN WITH BLEEDING DISORDERS

1-DEAMINO-8-D-ARGININE VASOPRESSIN: A NEW PHARMACOLOGICAL APPROACH TO THE MANAGEMENT OF HAEMOPHILIA AND VON WILLEBRAND'S DISEASE

1977 • 597 citations

Bernard-Soulier Syndrome

1998 • 552 citations

Desmopressin (DDAVP) in the Treatment of Bleeding Disorders: The First 20 Years

1997 • 415 citations

Desmopressin (DDAVP) in the Treatment of Bleeding Disorders: The First 20 Years

1997 • 412 citations

DIABETIC KETOACIDOSIS

1974 • 363 citations

Controlled trial of desmopressin in liver cirrhosis and other conditions associated with a prolonged bleeding time

1986 • 212 citations

Quantitative analysis of von Willebrand factor propeptide release in vivo: effect of experimental endotoxemia and administration of 1- deamino-8-D-arginine vasopressin in humans

1996 • 211 citations

Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects

1986 • 206 citations

DDAVP Use During Pregnancy

1998 • 164 citations

Use of DDAVP in inherited and acquired platelet dysfunction

1990 • 164 citations

Factor VIII inhibitors in mild and moderate‐severity haemophilia A

1998 • 132 citations

The Effect of Desmopressin on Reducing Blood Loss in Cardiac Surgery – A Meta-Analysis of Double-Blind, Placebo-Controlled Trials

1995 • 107 citations

Acquired von Willebrand Disease

1997 • 103 citations

Prospective Multicenter Study on Subcutaneous Concentrated Desmopressin for Home Treatment of Patients with von Willebrand Disease and Mild or Moderate Hemophilia A

1996 • 99 citations

Hyponatremia in patients with nocturnal enuresis treated with DDAVP

1996 • 98 citations

Biological effect of desmopressin in eight patients with type 2n (‘Normandy’) von Willebrand disease

1994 • 94 citations

Desmopressin - a haemostatic drug

1997 • 84 citations

Mediastinal Bleeding After Cardiopulmonary Bypass in Pediatric Patients

1996 • 80 citations

Platelet‐activating factor secreted by DDAVP‐treated monocytes mediates von willebrand factor release from endothelial cells

1993 • 80 citations

DDAVP in acquired hemophilia a: Case report and review of the literature

1993 • 76 citations

Use of desmopressin acetate to reduce blood transfusion requirements during cardiac surgery in patients with acetylsalicylic-acid-induced platelet dysfunction.

1994 • 74 citations

A Study of Desmopressin and Blood Loss during Spinal Fusion for Neuromuscular Scoliosis

1997 • 67 citations

DDAVP‐induced enhancement of platelet retention: Its dependence on platelet‐von Willebrand Factor and the platelet receptor GP IIb/IIIa

1992 • 66 citations

Mechanisms of platelet dysfunction and response to DDAVP in patients with congenital platelet function defects. A double-blind placebo-controlled trial.

1995 • 65 citations

The Effects of Desmopressin and 6% Hydroxyethyl Starch on Factor VIII

1996 • 65 citations

CD4+ T Cell Response to Factor VIII in Hemophilia A, Acquired Hemophilia, and Healthy Subjects

1999 • 65 citations

Mechanisms of Platelet Dysfunction and Response to DDAVP in Patients with Congenital Platelet Function Defects

1995 • 61 citations

DDAVP Therapy Controls Bleeding in Ehlers-Danlos Syndrome

1997 • 54 citations

Adenotonsillectomy in Children With von Willebrand Disease

1999 • 51 citations

DDAVP in type IIa von Willebrand's disease

1986 • 47 citations

Evidence of a Local Mechanism for Desmopressin-Induced Tissue-Type Plasminogen Activator Release in Human Forearm

1998 • 46 citations

Platelet aggregates as markers of platelet activation: Characterization of flow cytometric method suitable for clinical applications

1998 • 45 citations

Post-DDAVP Thrombocytopenia in Type 2B von Willebrand Disease Is not Associated with Platelet Consumption: Failure to Demonstrate Glycocalicin Increase or Platelet Activation

1999 • 45 citations

Clinical usefulness of desmopressin for prevention of surgical bleeding in patients with symptomatic heterozygous factor XI deficiency

1996 • 42 citations

Platelet aggregation at high shear is impaired in patients with congenital defects of platelet secretion and is corrected by DDAVP: correlation with the bleeding time.

1995 • 42 citations

DDAVP for type IIB von Willebrand disease [letter]

1989 • 42 citations

3 Acquired von Willebrand disease

1998 • 41 citations

DDAVP shortens the bleeding time in bernard-soulier syndrome

1988 • 41 citations

The role of platelet von Willebrand factor in platelet adhesion and thrombus formation: a study of 34 patients with various subtypes of type I von Willebrand disease

1994 • 41 citations

A new variant of Bernard‐Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV

1998 • 40 citations

Heparin, DDAVP and the Bleeding Time

1991 • 39 citations

Haemate P<sup>®</sup> in Children with von Willebrand’s Disease

1994 • 38 citations

Optimizing therapy with factor VIII/von Willebrand factor concentrates in von Willebrand disease

1998 • 37 citations

Burned patients are not resistant to the neuromuscular effects of mivacurium

1997 • 36 citations

Perioperative Management of von Willebrand's Disease in Otolaryngologic Surgery

1998 • 35 citations

The Influence of Desmopressin on Blood Loss During Spinal Fusion Surgery in Neuromuscular Patients

1998 • 35 citations

von Willebrand factor‐collagen binding activity is increased in newborns and infants

1995 • 34 citations

Desmopressin (DDAVP) in Bleeding Disorders of Childhood

1998 • 31 citations

1-desamino-8-arginine-vasopressin corrects the hemostatic defects in type 2B von Willebrand's disease

1996 • 31 citations

Evidence that DDAVP transiently improves hemostasis in Bernard-Soulier syndrome independent of von Willebrand-Factor

1993 • 29 citations

Response to 1-Deamino-8-<i>D</i>-Arginine Vasopressin in von Willebrand Disease

1994 • 29 citations

Treatment of refractory thrombocytopenic bleeding with 1-desamino-8-d-arginine vasopressin (desmopressin)

1988 • 28 citations

Management of children with von Willebrand disease undergoing adenotonsillectomy

1996 • 28 citations

Ehlers-Danlos syndrome, type VIII presenting with periodontitis and prolonged bleeding time

1995 • 28 citations

NEW FAMILIES WITH VON WILLEBRAND DISEASE TYPE 2M (VICENZA)

1997 • 27 citations

Patients With Prolonged Bleeding Time of Undefined Etiology, and Their Response to Desmopressin

1988 • 27 citations

Bernard‐Soulier syndrome in two Swedish families: Effect of DDAVP on bleeding time

1991 • 26 citations

The Bleeding Time in Pediatrics

1998 • 26 citations

Review of clinical experience of desmopressin in patients with congenital and acquired bleeding disorders

1997 • 25 citations

New variant of von Willebrand disease type II with markedly increased levels of von Willebrand factor antigen and dominant mode of inheritance: von Willebrand disease type IIC Miami

1993 • 25 citations

DDAVP Shortens Bleeding Time in Bernard-Soulier Syndrome

1994 • 24 citations

Use of desmopressin to prevent bleeding in surgery

2002 • 24 citations

Intranasal DDAVP induced increases in plasma von Willebrand factor alter the pharmacokinetics of high‐purity factor VIII concentrates in severe haemophilia A patients

1999 • 23 citations

Von Willebrand Disease in Childhood

1995 • 23 citations

Changes in factor VIII binding capacity of von Willebrand factor and factor VIII coagulant activity in two patients with type 2N von Willebrand disease after hemostatic treatment and during pregnancy.

1996 • 21 citations

Hemostatic and Fibrinolytic Response to Desmopressin in Uremic Patients

1997 • 18 citations

Protracted, gross hematuria in sickle cell trait: response to multiple doses of 1-desamino-8-D-arginine vasopressin

1996 • 18 citations

Platelet Activation and Aggregation Induced by Recombinant von Willebrand Factors Reproducing Four Type 2B von Willebrand Disease Missense Mutations

1998 • 18 citations

Management of severe chronic thrombocytopenia in von Willebrand's disease type 2B

1998 • 17 citations

Effect of a 15-Minute Infusion of DDAVP on the Pharmacokinetics and Pharmacodynamics of ™REVASC during a Four-Hour Intravenous Infusion in Healthy Male Volunteers

1997 • 14 citations

Central nervous system ischemia after varicella infection and desmopressin therapy for enuresis

1997 • 13 citations

Acute and delayed effects of endotoxin on rat sciatic nerve in vivo

1997 • 13 citations

Type IV Ehlers-Danlos syndrome with platelet δ -storage pool disease

1998 • 12 citations

Alpha-delta-storage-pool-disease der Thrombozyten: Verkürzung der Blutungszeit durch Gabe von 1-Desamino-8-D-Arginin-Vasopressin (DDAVP)

1999 • 11 citations

DDAVP REDUCES BLOOD LOSS AND TRANSFUSION IN CARDIAC SURGICAL PATIENTS WITH IMPAIRED PLATELET FUNCTION IDENTIFIED USING A POINT-OF-CARE TEST

1998 • 8 citations

DDAVP in Bleeding Disorders

1981 • 7 citations

Coagulation Changes Associated with the Hemolytic Uremic Syndrome

1998 • 7 citations

Investigation of type IIC von Willebrand disease.

1994 • 4 citations

The influence of D.D.A.V.P. on the survival of factor VIII in severe haemophiliacs

1985 • 4 citations

Von Willebrand-Syndrom - Blutungsrisiko bei HNO-Eingriffen im Kindesalter

1994 • 4 citations

PädiatrieEvaluation of Laboratory Tests Used to Monitor 1 -Deamino-8-D-Arginine Vasopressin Infusion: Preliminary Results

1997 • 3 citations

[Utility of desmopressin in 4 cases of thrombocytopathies associated with giant platelets].

1997 • 2 citations

Hermansky-Pudlak-Syndrom: Diagnosestellung und Therapiemöglichkeit mit DDAVP

1991 • 2 citations

DDAVP-Therapie bei mittelschwerer/leichter Hämophilie B

1997 • 1 citations

Protracted, gross hematuria in sickle cell trait: response to multiple doses of 1-desamino-8-D-arginine vasopressin

1996 • 1 citations