Effects of overexpression of basic helix–loop–helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells

Multilineage Potential of Adult Human Mesenchymal Stem Cells

1999 • 20,447 citations

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

1997 • 4,191 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

1997 • 1,463 citations

PPARγ: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth

2001 • 1,147 citations

Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model

2000 • 1,024 citations

Dec1 and Dec2 are regulators of the mammalian molecular clock

2002 • 654 citations

Retention of Multilineage Differentiation Potential of Mesenchymal Cells during Proliferation in Response to FGF

2001 • 565 citations

Inhibition of PPARγ2 Gene Expression by the HIF-1-Regulated Gene DEC1/Stra13

2002 • 454 citations

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

2001 • 444 citations

Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation

1999 • 419 citations

Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix–loop–helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells

1997 • 236 citations

Identification of Functional Hypoxia Response Elements in the Promoter Region of the DEC1 and DEC2 Genes

2002 • 222 citations

Molecular Characterization of the Novel Basic Helix–Loop–Helix Protein DEC1 Expressed in Differentiated Human Embryo Chondrocytes

1997 • 153 citations

SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.

1997 • 120 citations

A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation

2003 • 119 citations

SHARPs: MammalianEnhancer-of-Split- andHairy-Related Proteins Coupled to Neuronal Stimulation

1997 • 115 citations

Basic Helix-loop-helix Protein DEC1 Promotes Chondrocyte Differentiation at the Early and Terminal Stages

2002 • 108 citations

DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter

2003 • 108 citations

Functional analysis of the basic helix‐loop‐helix transcription factor DEC1 in circadian regulation

2004 • 107 citations

Stra13 Homodimers Repress Transcription through Class B E-box Elements

2002 • 99 citations

A new technique to expand human mesenchymal stem cells using basement membrane extracellular matrix

2003 • 99 citations

Molecular Cloning and Characterization of DEC2, a New Member of Basic Helix-Loop-Helix Proteins

2001 • 97 citations

Expression of the gene for Dec2, a basic helix–loop–helix transcription factor, is regulated by a molecular clock system

2004 • 91 citations

DEC1 is a downstream target of TGF-β with sequence-specific transcriptional repressor activities

2002 • 86 citations

Sharp-1/DEC2 Inhibits Skeletal Muscle Differentiation through Repression of Myogenic Transcription Factors

2004 • 81 citations

Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP

2004 • 65 citations

DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1

2004 • 47 citations

Induction of basic helix-loop-helix protein DEC1 (BHLHB2)/Stra13/Sharp2 in response to the cyclic adenosine monophosphate pathway

2001 • 42 citations

Dec1 and Dec2 Expression is Disrupted in the Suprachiasmatic Nuclei of Clock Mutant Mice

2004 • 31 citations

Expression of Stra13 during mouse endochondral bone development

2004 • 11 citations