Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Coordination of circadian timing in mammals

2002 • 4,132 citations

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

2002 • 2,248 citations

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

2000 • 2,232 citations

A novel method for real time quantitative RT-PCR.

1996 • 2,093 citations

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

1972 • 1,975 citations

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 • 1,915 citations

Extensive and divergent circadian gene expression in liver and heart

2002 • 1,498 citations

Molecular Analysis of Mammalian Circadian Rhythms

2001 • 1,428 citations

Circadian rhythms from flies to human

2002 • 979 citations

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

1999 • 894 citations

A transcription factor response element for gene expression during circadian night

2002 • 852 citations

Dec1 and Dec2 are regulators of the mammalian molecular clock

2002 • 654 citations

DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally

1990 • 410 citations

Antagonistic role of E4BP4 and PAR proteins in the circadian oscillatory mechanism

2001 • 374 citations

Multitissue Circadian Expression of Rat periodHomolog (rPer2) mRNA Is Governed by the Mammalian Circadian Clock, the Suprachiasmatic Nucleus in the Brain

1998 • 305 citations

Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP.

1993 • 293 citations

Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix–loop–helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells

1997 • 236 citations

Role of DBP in the Circadian Oscillatory Mechanism

2000 • 235 citations

Antiphase Circadian Expression betweenBMAL1andperiodHomologue mRNA in the Suprachiasmatic Nucleus and Peripheral Tissues of Rats

1998 • 235 citations

Identification of Functional Hypoxia Response Elements in the Promoter Region of the DEC1 and DEC2 Genes

2002 • 222 citations

Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms

2000 • 171 citations

Defective T cell activation and autoimmune disorder in Stra13-deficient mice

2001 • 167 citations

Circadian Expression of the Steroid 15 α-Hydroxylase (Cyp2a4) and Coumarin 7-Hydroxylase (Cyp2a5) Genes in Mouse Liver Is Regulated by the PAR Leucine Zipper Transcription Factor DBP

1999 • 163 citations

Rat liver cholesterol 7 alpha-hydroxylase. Pretranslational regulation for circadian rhythm.

1990 • 157 citations

Molecular Characterization of the Novel Basic Helix–Loop–Helix Protein DEC1 Expressed in Differentiated Human Embryo Chondrocytes

1997 • 153 citations

SHARPs: mammalian enhancer-of-split- and hairy-related proteins coupled to neuronal stimulation.

1997 • 120 citations

SHARPs: MammalianEnhancer-of-Split- andHairy-Related Proteins Coupled to Neuronal Stimulation

1997 • 115 citations

Immunochemical Study on the Electron Pathway from NADH to Cytochrome P-450 of Liver Microsomes

1978 • 113 citations

Basic Helix-loop-helix Protein DEC1 Promotes Chondrocyte Differentiation at the Early and Terminal Stages

2002 • 108 citations

DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter

2003 • 108 citations

Humoral signals mediate the circadian expression of rat period homologue (rPer2) mRNA in peripheral tissues

1998 • 106 citations

Stra13 Homodimers Repress Transcription through Class B E-box Elements

2002 • 99 citations

Sterol 14-Demethylase P450 (P45014DM*) Is One of the Most Ancient and Conserved P450 Species

1996 • 97 citations

Molecular Cloning and Characterization of DEC2, a New Member of Basic Helix-Loop-Helix Proteins

2001 • 97 citations

Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.

1994 • 82 citations

mSharp-1/DEC2, a Basic Helix-Loop-Helix Protein Functions as a Transcriptional Repressor of E Box Activity and Stra13 Expression

2003 • 68 citations

Structure and Chromosomal Assignment of the Sterol 12α-Hydroxylase Gene (CYP8B1) in Human and Mouse: Eukaryotic Cytochrome P-450 Gene Devoid of Introns

1999 • 65 citations

Insulin Is a Dominant Suppressor of Sterol 12 -Hydroxylase P450 (CYP8B) Expression in Rat Liver: Possible Role of Insulin in Circadian Rhythm of CYP8B

2000 • 51 citations

Cross-talk between hypoxic and circadian pathways: cooperative roles for hypoxia-inducible factor 1α and CLOCK in transcriptional activation of the vasopressin gene

2003 • 50 citations

Sterol 14-Demethylase P450 Activity Expressed in Rat Gonads: Contribution to the Formation of Mammalian Meiosis-Activating Sterol

1996 • 44 citations

The Basic Helix-Loop-Helix Protein, SHARP-1, Represses Transcription by a Histone Deacetylase-dependent and Histone Deacetylase-independent Mechanism

2001 • 40 citations

Structure, Evolution, and Liver-Specific Expression of Sterol 12 -Hydroxylase P450 (CYP8B)

1999 • 31 citations

Structural and Evolutionary Studies on Sterol 14-Demethylase P450 (CYP51), the Most Conserved P450 Monooxygenase: I. Structural Analyses of the Gene and Multiple Sizes of mRNA

1997 • 30 citations

Gene Structure and Chromosomal Location of a Human bHLH Transcriptional Factor DEC1-Stra13-SHARP-2/BHLHB2

2001 • 29 citations

Structural analysis of the gene encoding rat cholesterol alpha-hydroxylase, the key enzyme for bile acid biosynthesis.

1991 • 24 citations