Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein

1987 • 1,074 citations

Simian virus 40 DNA replication in vitro.

1984 • 562 citations

ANIMAL VIRUS DNA REPLICATION

1989 • 520 citations

An auxiliary protein for DNA polymerase-delta from fetal calf thymus.

1986 • 500 citations

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

1987 • 491 citations

Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin

1990 • 430 citations

[31] Tackling the protease problem in Saccharomyces cerevisiae

1991 • 427 citations

Binding and unwinding—How T antigen engages the SV40 origin of DNA replication

1990 • 404 citations

Cellular factors required for multiple stages of SV40 DNA replication in vitro.

1988 • 398 citations

Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA

1988 • 395 citations

Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells.

1985 • 380 citations

Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

1991 • 380 citations

A third essential DNA polymerase in S. cerevisiae

1990 • 360 citations

Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.

1987 • 355 citations

Replication of simian virus 40 origin-containing DNA in vitro with purified proteins.

1987 • 355 citations

Initiation Of Eukaryotic DNA Replication In Vitro

1989 • 343 citations

ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication

1989 • 342 citations

In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site.

1985 • 334 citations

Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells.

1990 • 327 citations

Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication

1989 • 286 citations

Localized melting and structural changes in the SV40 origin of replication induced by T-antigen.

1988 • 268 citations

Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis

1991 • 263 citations

Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.

1990 • 261 citations

Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template.

1987 • 260 citations

Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta.

1991 • 254 citations

Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and delta.

1989 • 252 citations

Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III.

1989 • 231 citations

Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro.

1989 • 209 citations

Simian virus 40 DNA replication in vitro: specificity of initiation and evidence for bidirectional replication.

1985 • 206 citations

Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1.

1990 • 205 citations

Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase.

1991 • 196 citations

Isolation of the gene encoding yeast DNA polymerase I

1985 • 194 citations

Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene

1990 • 193 citations

Unwinding of Duplex DNA from the SV40 Origin of Replication by T Antigen

1987 • 172 citations

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta.

1988 • 155 citations

DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene

1989 • 154 citations

Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta.

1989 • 148 citations

ATP-dependent formation of a specialized nucleoprotein structure by simian virus 40 (SV40) large tumor antigen at the SV40 replication origin.

1987 • 141 citations

ATP enhances the binding of simian virus 40 large T antigen to the origin of replication

1987 • 128 citations

Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system.

1990 • 127 citations

Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen

1990 • 122 citations

DNA polymerase III from Saccharomyces cerevisiae. I. Purification and characterization.

1988 • 116 citations

Targeting bacteriophage T7 RNA polymerase to the mammalian cell nucleus

1988 • 109 citations

Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation.

1989 • 94 citations

Requirement for two DNA polymerases in the replication of simian virus 40 DNA in vitro.

1989 • 84 citations

DNA polymerase I and DNA primase complex in yeast.

1984 • 81 citations

Simian virus 40 (SV40) large tumor antigen causes stepwise changes in SV40 origin structure during initiation of DNA replication.

1989 • 62 citations

A DNA primase that copurifies with the major DNA polymerase from the yeast Saccharomyces cerevisiae.

1984 • 58 citations

Expression in Escherichia coli of BCY1, the regulatory subunit of cyclic AMP-dependent protein kinase from Saccharomyces cerevisiae. Purification and characterization.

1987 • 54 citations

Purification of DNA polymerase delta as an essential simian virus 40 DNA replication factor

1991 • 49 citations