Analysis of a break in chromosome 14 mapping to the region of the immunoglobulin heavy chain locus.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH

1980 • 872 citations

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

1969 • 869 citations

Characteristic chromosomal abnormalities in biopsies and lymphoid‐cell lines from patients with burkitt and non‐burkitt lymphomas

1976 • 864 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

A highly polymorphic locus in human DNA.

1980 • 716 citations

Human Growth Hormone: Complementary DNA Cloning and Expression in Bacteria

1979 • 399 citations

ANTENATAL DIAGNOSIS OF SICKLE-CELL ANÆMIA BY D.N.A. ANALYSIS OF AMNIOTIC-FLUID CELLS

1978 • 380 citations

Human Immunoglobulin Heavy Chain Genes Map to a Region of Translocations in Malignant B Lymphocytes

1982 • 351 citations

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1982 • 323 citations

Identification of the Constant Chromosome Regions Involved in Human Hematologic Malignant Disease

1982 • 309 citations

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1980 • 306 citations

Molecular basis for familial isolated growth hormone deficiency.

1981 • 250 citations

DNA Sequences Mediating Class Switching in α-Immunoglobulins

1980 • 243 citations

Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing

1982 • 235 citations

Structure of human immunoglobulin gamma genes: implications for evolution of a gene family

1982 • 231 citations

The nucleotide sequence of a human immnnoglobulin C_γlgene

1982 • 158 citations

Genes for Growth Hormone, Chorionic Somatomammotropin, and Growth Hormone-Like Gene on Chromosome 17 in Humans

1980 • 158 citations

Genes for immunoglobulin heavy chains and for α1-antitrypsin are localized to specific regions of chromosome 14q

1982 • 139 citations

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

1981 • 138 citations

Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes.

1982 • 126 citations

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing

1980 • 121 citations

Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.

1980 • 97 citations

Nucleotide Sequence of a Human Immunoglobulin Cγ4 Gene

1981 • 91 citations

Assignment of first random restriction fragment length polymorphism (RFLP) locus ((D14S1) to a region of human chromosome 14.

1982 • 78 citations

Distribution of spontaneous chromosome breaks in man

1979 • 72 citations

Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells.

1982 • 58 citations

Comparison of phenotypic expression with genotypic transformation by using cloned, selectable markers.

1982 • 24 citations

Highly polymorphic DNA site D14S1 maps to the region of Burkitt lymphoma translocation and is closely linked to the heavy chain γ1 immunoglobulin locus

1982 • 20 citations

Introduction and Recovery of a Selectable Bacterial Gene from the Genome of Mammalian Cells

1982 • 16 citations

Comparison of Phenotypic Expression with Genotypic Transformation by Using Cloned, Selectable Markers

1982 • 8 citations