Structure of human immunoglobulin gamma genes: implications for evolution of a gene family

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Repeated Sequences in DNA

1968 • 2,836 citations

Why genes in pieces?

1978 • 2,256 citations

[31] Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acids

1971 • 1,605 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning

1977 • 951 citations

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

1969 • 869 citations

Genes in pieces: were they ever together?

1978 • 440 citations

Implications of RNA⋅RNA Splicing in Evolution of Eukaryotic Cells

1978 • 333 citations

Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

1979 • 329 citations

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

1982 • 323 citations

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1980 • 306 citations

Nucleotide sequence divergence and functional constraint in mRNA evolution.

1980 • 249 citations

Cloning and complete nucleotide sequence of mouse immunoglobulin γ1 chain gene

1979 • 230 citations

Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes

1981 • 219 citations

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

1980 • 213 citations

Human immunoglobulin heavy chain genes: evolutionary comparisons of Cμ, Cδ and Cγ genes and associated switch sequences

1981 • 205 citations

Mapping of Heavy Chain Genes for Mouse Immunoglobulins M and D

1980 • 188 citations

Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences

1981 • 173 citations

Exon shuffling generates an immunoglobulin heavy chain gene.

1980 • 146 citations

Primary structure of the "hinge" region of human IgG3. Probable quadruplication of a 15-amino acid residue basic unit.

1977 • 136 citations

Cloning of human immunoglobulin μ gene and comparison with mouse μ gene

1980 • 124 citations

Sequence of the Cloned Gene for the Constant Region of Murine γ2b Immunoglobulin Heavy Chain

1979 • 117 citations

Complete nucleotide sequence of mouse imunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes

1980 • 108 citations

Ordering of mouse immunoglobulin heavy chain genes by molecular cloning

1981 • 101 citations

Evolutionary approach to the question of immunoglobulin heavy chain switching: evidence from cloned human and mouse genes.

1980 • 97 citations

Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a γ4 chain

1970 • 96 citations

Rearrangements of Immunoglobulin Genes during Differentiation and Evolution

1981 • 95 citations

Complete nucleotide sequence of immunoglobulin γ2b chain gene cloned from newborn mouse DNA

1980 • 93 citations

Recombination activities of E. coli RecA protein

1981 • 87 citations

Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer.

1980 • 82 citations

Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster.

1981 • 70 citations

Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains.

1982 • 67 citations

The complete nucleotide sequence of mouse immunoglobulin γ2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer

1981 • 66 citations

Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains

1980 • 65 citations

Genetic Markers of the Heavy Chain Subgroups of Human G Globulin

1967 • 61 citations

Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin λ2b-chain gene

1980 • 54 citations

Linkage of the four gamma subclass heavy chain genes.

1981 • 39 citations

Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination.

1979 • 36 citations

The primary structure of a human IgG2 heavy chain: genetic, evolutionary, and functional implications.

1980 • 30 citations

Recombination, mutation, or constitutive expression at a Gm locus and familial hypergammaglobulinemia.

1977 • 23 citations

Immunoglobulin γ1 heavy chain gene: Structural gene sequences cloned in a bacterial plasmid

1980 • 22 citations

Complete nucleotide sequence of mouse immunoglobulin μ gene and comparison with other immunoglobulin heavy chain genes

1983 • 9 citations