Host Defenses Against Pneumocystis carinii in Mice Selectively Depleted of CD4+ Lymphocytes

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Acquired Immunodeficiency Syndrome: Epidemiologic, Clinical, Immunologic, and Therapeutic Considerations

1984 • 871 citations

The Risk ofPneumocystis cariniiPneumonia among Men Infected with Human Immunodeficiency Virus Type 1

1990 • 682 citations

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

1990 • 250 citations

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice.

1990 • 242 citations

Importance of endogenous tumor necrosis factor alpha and gamma interferon in host resistance against Pneumocystis carinii infection

1992 • 173 citations

Activation of tissue macrophages from AIDS patients: in vitro response of AIDS alveolar macrophages to lymphokines and interferon-gamma.

1985 • 129 citations

Inflammatory Responses to Pneumocystis carinii in Mice Selectively Depleted of Helper T Lymphocytes

1991 • 120 citations

Reduction in intensity of Pneumocystis carinii pneumonia in mice by aerosol administration of gamma interferon

1991 • 120 citations

Species heterogeneity in macrophage expression of the CD4 antigen.

1987 • 103 citations

Lung-specific delivery of cytokines induces sustained pulmonary and systemic immunomodulation in rats.

1988 • 88 citations

T4+ Cell Production of Interferon Gamma and the Clinical Spectrum of Patients at Risk for and With Acquired Immunodeficiency Syndrome

1988 • 44 citations

Immunopathogenesis of Pneumocystis carinii infection.

1991 • 28 citations

Effects of human immunodeficiency virus on pulmonary host defenses.

1989 • 25 citations

Clinical relevance of animal models of Pneumocystis carinii pneumonia

1984 • 9 citations