Immunoregulation through CD8 (Ly‐2): state of aggregation with the α/β/CD3 T cell receptor controls interleukin 2‐dependent T cell growth

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Cytochemical Identification of Monocytes and Granulocytes

1971 • 2,735 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen.

1975 • 1,105 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

Perturbation of the T4 molecule transmits a negative signal to T cells.

1985 • 335 citations

The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.

1983 • 325 citations

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

1987 • 265 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

1979 • 173 citations

Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells.

1985 • 167 citations

Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor

1988 • 166 citations

Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.

1986 • 159 citations

Cross-linking of T3 (CD3) with T4 (CD4) enhances the proliferation of resting T lymphocytes.

1987 • 136 citations

Effective activation of resting mouse T lymphocytes by cross‐linking submitogenic concentrations of the T cell antigen receptor with either Lyt‐2 or L3T4

1987 • 120 citations

Cross‐linking of the T cell receptor complex with the subset‐specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells

1987 • 117 citations

A speculative view of the multicomponent nature of T cell antigen recognition

1986 • 117 citations

Evidence for an association between CD8 molecules and the T cell receptor complex on cytotoxic T cells.

1987 • 83 citations

Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function.

1984 • 76 citations

Quantitative studies on T cell diversity. I. Determination of the precursor frequencies for two types of streptococcus A-specific helper cells in nonimmune, polyclonally activated splenic T cells.

1980 • 75 citations

Accessory cell function in the Con A response: role of Ia-positive and Ia-negative accessory cells.

1985 • 72 citations

Expression and function of CD8 in a murine T cell hybridoma.

1987 • 63 citations

Network regulation among T cells; Conclusions from limiting dilution experiments

1983 • 54 citations

Network Regulation among T Cells: Qualitative and Quantitative Studies on Suppression in the Non‐Immune State

1984 • 49 citations

Monoclonal anti-Lyt-2.2 antibody blocks lectin-dependent cellular cytotoxicity of H-2-negative target cells.

1984 • 47 citations

Antibody producing human-human hybridomas. II. Derivation and characterization of an antibody specific for human leukemia cells.

1984 • 44 citations

The influence of valence on the functional activities of monoclonal anti-L3T4 antibodies. Discrimination of signaling from other effects.

1987 • 34 citations

Heterologous cross-linking of Lyt-2 (CD8) to the alpha beta-T cell receptor is more effective in T cell activation than homologous alpha beta-T cell receptor cross-linking.

1988 • 20 citations

Antibodies to the L3T4 and Lyt-2 molecules interfere with antigen receptor-driven activation of cloned murine T cells.

1987 • 19 citations

Selective stimulation of human t lymphocyte subsets by heteroconjugates of antibodies to the t cell receptor and to subset-specific differentiation antigens

1988 • 19 citations