Quantitative studies on T cell diversity. I. Determination of the precursor frequencies for two types of streptococcus A-specific helper cells in nonimmune, polyclonally activated splenic T cells.

Towards a network theory of the immune system.

1974 • 3,379 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Antitrinitrophenyl (TNP) Plaque Assay. Primary Response of Balb/c Mice to Soluble and Particulate Immunogen

1969 • 935 citations

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.

1979 • 522 citations

Monoclonal cytolytic T-cell lines.

1979 • 364 citations

Expression and Function of Idiotypes on Lymphocytes

1978 • 340 citations

Fine specificity of a continuously growing killer cell clone specific for H-Y antigen

1979 • 317 citations

Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cells.

1978 • 316 citations

Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: suppressor and helper activities are inherent properties of distinct T-cell subclasses.

1976 • 279 citations

Idiotype‐specific T helper cells are required to induce idiotype‐positive B memory cells to secrete antibody

1978 • 268 citations

The Search for Antibodies with Molecular Uniformity

1970 • 258 citations

Antigen-Binding, Idiotypic T-Lymphocyte Receptors

1977 • 230 citations

Antigen Receptors of T Helper Cells

1977 • 200 citations

Proliferation of Murine Thymic Lymphocytes in Vitro Is Mediated by the Concanavalin A-Induced Release of a Lymphokine (Costimulator)

1976 • 151 citations

Regulation of the Immune Response by T-Cell Subclasses

1977 • 150 citations

Recognition of idiotypes in lymphocyte interactions II. Antigen‐independent cooperation between T and B lymphocytes that possess similar and complementary idiotypes

1978 • 149 citations

Studies on T lymphocyte activation I. Requirements for the mitogen‐dependent production of T cell growth factors

1979 • 146 citations

Cloned T-Cell Lines with Specific Cytolytic Activity

1979 • 127 citations

Frequencies of mitogen-reactive B cells in the mouse. II. Frequencies of B cells producing antibodies which lyse sheep or horse erythrocytes, and trinitrophenylated or nitrodophenylated sheep erythrocytes

1977 • 125 citations

Idiotypic analysis of lymphocytes in vitro. I. Specificity and heterogeneity of B and T lymphocytes reactive with anti-idiotypic antibody.

1976 • 117 citations

Recognition of idiotypes in lymphocyte interactions I. Idiotypic selectivity in the cooperation between T and B lymphocytes

1978 • 109 citations

Absolute frequencies of lipopolysaccharide-reactive B cells producing A5A idiotype in unprimed, streptococcal A carbohydrate-primed, anti-A5A idiotype-sensitized and anti-A5A idiotype-suppressed A/J mice.

1977 • 104 citations

Quantitative studies on the precursors of cytotoxic lymphocytes. I. Characterization of a clonal assay and determination of the size of clones derived from single precursors.

1977 • 103 citations

Histocompatibility antigen-activated cytotoxic T lymphocytes. I. Estimates of the absolute frequency of killer cells generated in vitro.

1977 • 95 citations

Antigen-specific T-helper cells stimulate H-2-compatible and H-2-incompatible B-cell blasts polyclonally.

1980 • 94 citations

Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells.

1975 • 94 citations

Absence of an antigen‐specific helper T cell required for the expression of the Tn 15 idiotype in mice treated with anti‐μ antibody

1980 • 92 citations

T cell receptor idiotypes are controlled by genes in the heavy chain linkage group and the major histocompatibility complex

1977 • 77 citations

The fine specificity of regulatory T cells IV. Idiotypic complementarity and antigen‐bridging interactions in the anti‐lysozyme response

1979 • 77 citations

Conditions Determining the Generation and Expression of T Helper Cells

1977 • 64 citations

Idiotype suppression. III. Induction of unresponsiveness to sensitization with anti-idiotypic antibody: identification of the cell types tolerized in high zone and in low zone, suppressor cellmediated, idiotype suppression

1978 • 53 citations

Sheep red blood cell-specific helper activity in rat thoracic duct lymphocyte populations positively selected for reactivity to specific strong histocompatibility alloantigens.

1976 • 45 citations

Alloantigen receptors on activated T cells in mice. I. Binding of alloantigens and anti-idiotypic antibodies to the same receptors.

1978 • 45 citations

Experimental approaches tohomogenous antibody populations. iIndividual antigenic specificity, cross specificity and diversity of human antibodies.

1970 • 42 citations

T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response.

1975 • 42 citations

Developmental and communicative interrelations of Ly123 and Ly1 cell sets.

1980 • 41 citations

Correlated expression of V_H framework and V_Hidiotypic determinants on T helper cells and on functionally undefined T cells binding group A streptococcal carbohydrate

1980 • 41 citations

Amplification of B cell clones forming antibody to the 2,4‐dinitrophenyl group

1972 • 34 citations

Generation of effector cells from T cell subsets. II. Lyt 123 T cells contain the precursors for all primary cytotoxic effector cells and for cells involved in the regulation of cytotoxic responses

1980 • 29 citations

The Generation of Effector Functions as a Result of Communication between Subclasses of T Lymphocytes

1980 • 4 citations

Genetic control of idiotypes of T cell receptors for antigen

1978 • 4 citations