Amyotrophic lateral sclerosis: An unconventional autoimmune disease?

Antibody to acetylcholine receptor in myasthenia gravis

1998 • 1,149 citations

Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value

1976 • 1,123 citations

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

1975 • 937 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside

1988 • 597 citations

The gangliosides

1964 • 500 citations

Axonal uptake and retrograde transport of exogenous proteins in the hypoglossal nerve

1971 • 418 citations

Functional Activities of Autoantibodies to Acetylcholine Receptors and the Clinical Severity of Myasthenia Gravis

1982 • 384 citations

Proximal axonal enlargement in motor neuron disease

1968 • 359 citations

Human motor neuron diseases.

1982 • 352 citations

Molecular Cloning and Expression of Neuroleukin, a Neurotrophic Factor for Spinal and Sensory Neurons

1986 • 332 citations

Ganglioside structures and distribution: Are they localized at the nerve ending?

1978 • 307 citations

Ultrastructural localization of cell membrane G _M1 ganglioside by cholera toxin

1977 • 292 citations

IgM in a human neuropathy related to paraproteinemia binds to a carbohydrate determinant in the myelin-associated glycoprotein and to a ganglioside.

1984 • 258 citations

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

1979 • 229 citations

Tetanus Toxin: Direct Evidence for Retrograde Intraaxonal Transport

1975 • 224 citations

Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patientwith motor neuron disease

1986 • 208 citations

The mode of action of immunosuppressive agents.

1975 • 201 citations

Handbook of Neurochemistry

1983 • 187 citations

Monoclonal IgM with unique specificity to gangliosides GM ₁ and GD _1b and to lacto‐ N ‐tetraose associated with human motor neuron disease

1988 • 183 citations

Immunochemical Reactions of Lipids

2015 • 174 citations

Antibodies to glycosphingolipids in patients with multiple sclerosis and SLE.

1984 • 169 citations

Serum antibodies to GM ₁ ganglioside in amyotrophic lateral sclerosis

1988 • 155 citations

Axonal and transneuronal transport of wheat germ agglutinin demonstrated by immunocytochemistry

1982 • 140 citations

TISSUE CULTURE STUDIES OF DEMYELINATION^*

1965 • 137 citations

Amyotrophic Lateral Sclerosis

1986 • 105 citations

Pneumococcal polysaccharides induce antibody formation by human B lymphocytes in vitro.

1985 • 105 citations

Patterns of serum IgM antibodies to GM1 and GD1a gangliosides in amyotrophic lateral sclerosis

1989 • 102 citations

The clinical spectrum of hexosaminidase deficiency diseases

1981 • 101 citations

Endocytosis of cholera toxin into neuronal GERL.

1978 • 101 citations

Motor neuron disease and plasma cell dyscrasia

1986 • 94 citations

Amyotrophic Lateral Sclerosis: Effect of Serum on Anterior Horn Cells in Tissue Culture

1973 • 91 citations

A Double-blind Study of the Effectiveness of Cyclosporine in Amyotrophic Lateral Sclerosis

1988 • 91 citations

Gangliosides of the Neuron: Localization and Origin

1976 • 87 citations

GANGLIOSIDE COMPOSITION AND CONTENT OF RAT‐BRAIN SUBCELLULAR FRACTIONS

1973 • 85 citations

Macroglobulinemia with peripheral neuropathy simulating motor neuron disease

1982 • 83 citations

Research Progress in Motor Neurone Disease

1985 • 82 citations

Inhibition of Terminal Axonal Sprouting by Serum from Patients with Amyotrophic Lateral Sclerosis

1984 • 82 citations

SPINAL CORD INJURY FOLLOWING ELECTRICAL ACCIDENTS

1975 • 69 citations

Neuron specific in vitro cytotoxicity of sera from patients with amyotrophic lateral sclerosis

1982 • 67 citations

Differential Reactivities of Fetal and Adult Human Erythrocytes to Antisera Directed Against Glycolipids of Human Erythrocytes¹

1969 • 66 citations

Immunostaining of motor nerve terminals by IgM M protein with activity against gangliosides GM ₁ and GD _lb from a patient with motor neuron disease

1988 • 64 citations

EVIDENCE FOR IMMUNE-COMPLEX FORMATION IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS

1976 • 63 citations

Plasmapheresis With Immunosuppression in Amyotrophic Lateral Sclerosis

1983 • 57 citations

Plasmapheresis and the Immunobiology of Myasthenia Gravis

1980 • 55 citations

Failure of Immunosuppression With a Ten- to 14-Day Course of High-Dose Intravenous Cyclophosphamide to Alter the Progression of Amyotrophic Lateral Sclerosis

1986 • 53 citations

Localization of neural epitopes that bind to IgM monoclonal autoantibodies (M-proteins) from two patients with motor neuron disease

1989 • 51 citations

Uptake of plasma IgG by CNS motoneurons

1988 • 49 citations

Antibodies to Gangliosides and Myelin Autoantigens Are Produced in Mice Following Sciatic Nerve Injury

1982 • 49 citations

Retrograde axonal transport of lead in rat sciatic nerve

1981 • 47 citations

Amyotrophic Lateral Sclerosis: Recent Research Trends

1977 • 45 citations

Toxicity of motor neurone disease serum for myelin in tissue culture.

1965 • 45 citations

Retrograde transport and differential accumulation of serum proteins in motor neurons

1987 • 44 citations

Histocompatibility Typing in Amyotrophic Lateral Sclerosis

1976 • 43 citations

Two processes for B-Cell triggering by T-independent antigens as evidenced by the effect of azathioprine

1976 • 43 citations

Pneumococcal polysaccharides induce antibody formation by human B lymphocytes in vitro.

1985 • 42 citations

Antineural antibodies in the serum of patients with amyotrophic lateral sclerosis

1987 • 41 citations

Prolonged metoclopramideinduced dyskinetic reaction

1984 • 39 citations

Amyotrophic Lateral Sclerosis Sera Applied to Cultured Motor Neurons

1974 • 39 citations

Leçons sur les maladies du système nerveux

1896 • 38 citations

Immune Reactions of Lipids and Lipid Model Membranes

1977 • 38 citations

The mode of action of immunosuppressive agents

1986 • 37 citations

Differential effects of prednisone and cyclophosphamide on autoantibodies in human neuromuscular disorders

1989 • 36 citations

Gammopathy with proximal motor axonopathy simulating motor neuron disease

1986 • 36 citations

Preparation and Properties of Antibodies to G_D3 and G_M1 Gangliosides

1980 • 35 citations

Motor neuron disease and toxic metals.

1982 • 34 citations

Anti-inflammatory Effects of Corticosteroids

1984 • 32 citations

Neuropathy and motor neuron syndromes associated with plasma cell disease

2009 • 31 citations

The effect of serum from ALS patients on organotypic nerve and muscle tissue cultures

1975 • 29 citations

Cultured rat spinal cord neurons: Interaction with motor neuron disease immunoglobulins

1985 • 27 citations

Motor neuron disease and paraproteinemia

1987 • 27 citations

Axonal transport of antibodies to subcellular and protein fractions of rat brain

1985 • 27 citations

Spinal muscular atrophy secondary to macroglobulinemia

1968 • 26 citations

Antibodies to phospholipids and liposomes: binding of antibodies to cells

1987 • 23 citations

Amyotrophic lateral sclerosis and paraproteinemia

1982 • 22 citations

MACROGLOBULINEMIA WALDENSTRÖM AND MOTOR NEURON SYNDROME

1977 • 21 citations

Immunoblot analysis of circulating antibodies against muscle proteins in amyotrophic lateral sclerosis and other neurologic diseases

1986 • 17 citations

E.N.T. TEXTBOOK

1953 • 15 citations

Immunoregulatory and activated T cells in amyotrophic lateral sclerosis patients

1985 • 13 citations

RESULTS OF TREATMENT OF CERTAIN DISEASES OF THE CENTRAL NERVOUS SYSTEM WITH ACTH AND CORTICOSTEROIDS

2009 • 12 citations

Sera from patients with motor neuron disease and associated paraproteinaemia fail to inhibit experimentally induced sprouting of motor nerve terminals.

1986 • 6 citations