Effect of hyperlipidemic serum on lipid peroxidation, synthesis of prostacyclin and thromboxane by cultured endothelial cells: Protective effect of antioxidants

Free radicals in biology and medicine

1991 • 17,840 citations

Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.

1984 • 826 citations

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

1976 • 606 citations

Selection and characterization of bovine aortic endothelial cells

1978 • 417 citations

STUDIES ON THE ROLE OF LIPOPEROXIDES IN HUMAN PATHOLOGY

1952 • 347 citations

Lipid peroxidation and endothelial cell injury: implications in atherosclerosis

1988 • 335 citations

ASSAY FOR SERUM LIPID PEROXIDE LEVEL AND ITS CLINICAL SIGNIFICANCE

1982 • 302 citations

Bovine endothelial cells in culture produce thromboxane as well as prostacyclin.

1981 • 300 citations

Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits

1978 • 256 citations

LIPID PEROXIDATION IN RELATION TO PROSTACYCLIN AND THROMBOXANE PHYSIOLOGY AND PATHOPHYSIOLOGY

1983 • 184 citations

Dietary Supplementation with Vitamin E in Hyperlipoproteinemias: Effects on Plasma Lipid Peroxides, Antioxidant Activity, Prostacyclin Generation and Platelet Aggregability

1985 • 121 citations

Modulation of platelet thromboxane A2 and arterial prostacyclin by dietary vitamin E

1981 • 99 citations

Exposure to fatty acid increases human low density lipoprotein transfer across cultured endothelial monolayers.

1985 • 73 citations

Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells.

1980 • 64 citations

Linoleic acid hydroperoxide increases the transfer of albumin across cultured endothelial monolayers

1986 • 53 citations

Selenium enhances prostacyclin production by cultured endothelial cells: Possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement

1984 • 51 citations

Cultured endothelial cells increase their capacity to synthesize prostacyclin following the formation of a contact inhibited cell monolayer

1983 • 40 citations

LDL cytotoxicity The state of the art

1984 • 33 citations

ROLE OF GSH PEROXIDASE IN LIPID PEROXIDE METABOLISM

1982 • 31 citations

The Problems and the Promise of Prostaglandin Influences in Atherogenesis

1985 • 29 citations

Influence of dietary vitamin E on platelet tnromboxane A2 and vascular prostacyclin I2 in rabbit

1982 • 19 citations

Prostacyclin production by endothelial cells. Effects of sera from normal and hyperlipidemic subjects.

1985 • 12 citations

Lipid peroxides, glutathione peroxidase, prostacyclin and cell cycle stages in normal and atherosclerotic Japanese quail arteries

1989 • 11 citations