LDL cytotoxicity The state of the art

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Hyperlipidemia and Atherosclerosis

1976 • 746 citations

Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

1983 • 623 citations

Lipoprotein oxidation and lipoprotein-induced cytotoxicity.

1983 • 545 citations

Cultured human endothelial cells generate tissue factor in response to endotoxin.

1983 • 516 citations

LDL-induced cytotoxicity and its inhibition by HDL in human vascular smooth muscle and endothelial cells in culture

1979 • 512 citations

Lipid peroxide level in plasma of diabetic patients

1979 • 463 citations

George Lyman Duff Memorial Lecture. Atherosclerosis: a problem of the biology of arterial wall cells and their interactions with blood components.

1981 • 456 citations

STUDIES ON THE ROLE OF LIPOPEROXIDES IN HUMAN PATHOLOGY

1952 • 347 citations

Lipid peroxide levels of serum lipoprotein fractions of diabetic patients

1981 • 305 citations

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

1978 • 276 citations

Injury to human endothelial cells in culture induced by low density lipoproteins

1979 • 231 citations

Regulatory Serum Lipoproteins: Regulation of Lymphocyte Stimulation by a Species of Low Density Lipoprotein

1976 • 187 citations

Effect of high and low density lipoproteins on proliferation of cultured bovine vascular endothelial cells.

1980 • 185 citations

Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B.

1980 • 126 citations

Apoprotein E suppresses phytohemagglutinin-activated phospholipid turnover in peripheral blood mononuclear cells.

1982 • 107 citations

LDL-induced cytotoxicity and its inhibition by anti-oxidant treatment in cultured human endothelial cells and fibroblast

1983 • 100 citations

Inhibition of lymphocyte proliferation stimulated by lectins and allogeneic cells by normal plasma lipoproteins.

1977 • 99 citations

Maintenance of integrity in aortic endothelium.

1980 • 95 citations

Characterization of low density lipoprotein-like particle in the human aorta from grossly normal and atherosclerotic regions

1979 • 91 citations

Low density lipoproteins (LDL) are carriers for lipid peroxides and inhibit prostacyclin (PGI2) biosynthesis in arteries.

1980 • 89 citations

Experiments on the Degradation of Lipoproteins from Serum

1954 • 83 citations

Plasma Lipoprotein Induction and Suppression of the Generation of Cellular Procoagulant Activity in Vitro

1981 • 81 citations

Inhibition of lymphoproliferation by hyperlipoproteinemic plasma.

1976 • 75 citations

Identification of a lymphocyte surface receptor for low density lipoprotein inhibitor, an immunoregulatory species of normal human serum low density lipoprotein.

1978 • 67 citations

Effects of moderate hypercholesterolemia on rabbit endothelium.

1981 • 64 citations

In Vivo Suppression of the Primary Immune Response by a Species of Low Density Serum Lipoprotein

1977 • 63 citations

9th international symposium on atherosclerosis

1991 • 61 citations

Abnormal effects of hypertriacylglycerolemic very low-density lipoproteins on 3-hydroxy-3-methylglutaryl-CoA reductase activity and viability of cultured bovine aortic endothelial cells

1980 • 61 citations

Injury to cultured endothelial cells induced by low density lipoproteins: protection by high density lipoproteins

1979 • 60 citations

Absence of enhanced intimal thickening in the response of the carotid arterial wall to endothelial injury in hypercholesterolemic rats.

1976 • 52 citations

Lipid peroxides and alpha-tocopherol in rat streptozotocin-induced diabetes mellitus.

1982 • 47 citations

Inhibition of lymphocyte mitogenesis by autoxidized low-density lipoprotein

1978 • 46 citations

In Vitro Injury of Porcine Aortic Endothelial Cells by Very-Low-Density Lipoproteins from Diabetic Rat Serum

1982 • 43 citations

Immunoregulation by low density lipoproteins in man: low density lipoprotein inhibits mitogen-stimulated human lymphocyte proliferation after initial activation.

1983 • 36 citations

Effects of hydrogen peroxide on lipoproteins and associated lipids

1969 • 34 citations

Endothelial regeneration in hypertensive and genetically hypercholesterolemic rats.

1983 • 27 citations

In vitro injury of porcine aortic endothelial cells by very-low-density lipoproteins from diabetic rat serum

1982 • 19 citations

In vitro effects of hyperlipoproteinemic sera on human endothelium: Inhibition of endothelial cell migration by familial hypercholesterolemic sera

1980 • 14 citations

Injury to human cells in culture induced by low density lipoprotein: An effect independent of receptor binding and endocytotic uptake of low density lipoprotein

1982 • 14 citations

Injury to human cells in culture induced by low density lipoprotein: An effect independent of receptor binding and endocytotic uptake of low density lipoprotein

1982 • 14 citations

Studies on the Cellular Basis of Atherosclerosis: The Effects of Atherosclerosis Risk Factors on Platelets and the Vascular Endothelium

1981 • 14 citations

Inhibition of In Vitro Lymphocyte Response by Streptozotocin-induced Diabetic Rat Serum: A Function of Very-Low-Density Lipoproteins

1982 • 12 citations

Interaction of Lipoproteins with Cultured Endothelial Cells

2015 • 12 citations

Injury to cultured human fibroblasts induced by low density lipoproteins: Potentiating and protective factors

1982 • 11 citations

Very low density lipoprotein hematopoiesis inhibitor from rat plasma.

1980 • 10 citations

Injury to cultured human fibroblasts induced by low density lipoproteins: Potentiating and protective factors

1982 • 10 citations

Modulation of peripheral blood mononuclear cell cyclic adenosine monophosphate levels by human very low density lipoprotein

1981 • 8 citations

Characterization of a very-low-density lipoprotein (VLDL)-associated cytotoxic factor

1981 • 8 citations

The stability of human serum lipoproteins, in vitro.

1972 • 7 citations

Rat hematopoietic cell receptors for very low density lipoprotein (VLDL) growth inhibitor.

1981 • 5 citations

Deficiency in the ability of serum from pigs on an atherogenic diet to stimulate the migration of 3T3 cells in culture.

1979 • 4 citations