A Macrophage Invasion Mechanism of Pathogenic Mycobacteria

Lack of Acidification inMycobacteriumPhagosomes Produced by Exclusion of the Vesicular Proton-ATPase

1994 • 1,289 citations

Identification of the C3bi receptor of human monocytes and macrophages by using monoclonal antibodies.

1983 • 674 citations

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

1995 • 496 citations

Simple and rapid measurement of human T lymphocytes and their subclasses in peripheral blood.

1980 • 463 citations

Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins.

1990 • 391 citations

CHROMATOGRAPHIC RESOLUTION OF THE FIRST COMPONENT OF HUMAN COMPLEMENT INTO THREE ACTIVITIES

1963 • 377 citations

Immunopathology of tuberculosis: roles of macrophages and monocytes

1996 • 308 citations

FORMATION AND FUNCTIONAL SIGNIFICANCE OF A MOLECULAR COMPLEX DERIVED FROM THE SECOND AND THE FOURTH COMPONENT OF HUMAN COMPLEMENT

1967 • 244 citations

Mycobacterium avium Infection and AIDS: A Therapeutic Dilemma in Rapid Evolution

1991 • 220 citations

Macrophage activation: lipoarabinomannan from avirulent and virulent strains of Mycobacterium tuberculosis differentially induces the early genes c-fos, KC, JE, and tumor necrosis factor-alpha.

1993 • 216 citations

Phagocytosis of Mycobacterium leprae by human monocyte-derived macrophages is mediated by complement receptors CR1 (CD35), CR3 (CD11b/CD18), and CR4 (CD11c/CD18) and IFN-gamma activation inhibits complement receptor function and phagocytosis of this bacterium.

1991 • 166 citations

Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

1977 • 130 citations

THE SECOND COMPONENT OF HUMAN COMPLEMENT: ITS ISOLATION, FRAGMENTATION BY C'1 ESTERASE, AND INCORPORATION INTO C'3 CONVERTASE

1968 • 127 citations

Immunoglobulin-mediated phagocytosis by human monocytes requires protein kinase C activation. Evidence for protein kinase C translocation to phagosomes.

1992 • 123 citations

Leukocyte adhesion-deficient neutrophils fail to amplify phagocytic function in response to stimulation. Evidence for CD11b/CD18-dependent and -independent mechanisms of phagocytosis.

1991 • 105 citations

Mycobacteria-macrophage interactions. Macrophage phenotype determines the nonopsonic binding of Mycobacterium tuberculosis to murine macrophages.

1993 • 104 citations

Control of complement synthesis and secretion in bronchoalveolar and peritoneal macrophages.

1980 • 70 citations

Immune complexes and antibodies to BCG in sera from patients with mycobacterial infections.

1980 • 50 citations

C′2ad, an inactive derivative of C′2 released during decay of EAC′4,2a

1966 • 50 citations

Reversible adsorption of C′2 by EAC′4: Role of Mg2+, enumeration of competent SAC′4, two-step nature of C′2a fixation and estimation of its efficiency

1966 • 47 citations

Immune complexes in the spectrum of tuberculosis

1981 • 41 citations

Tuberculosis—Immunopathogenesis and Therapy

1993 • 20 citations

Complement activation in pulmonary tuberculosis

1990 • 19 citations

Human phagocyte respiratory burst by Mycobacterium bovis BCG and M. leprae: functional activation by BCG is mediated by complement and its receptors on monocytes.

1992 • 9 citations