Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

Biological properties of carrageenan

1972 • 474 citations

Mechanism of Immunologically Specific Killing of Tumour Cells by Macrophages

1972 • 435 citations

Effect of Cyclic AMP on Release of Lysosomal Enzymes from Phagocytes

1971 • 380 citations

Mammalian glycosidases. Distribution in the body

1959 • 354 citations

Collagenase Production by Endotoxin-Activated Macrophages

1974 • 303 citations

Protection of mice against Babesia, and Plasmodium with BCG

1976 • 289 citations

Properdin System and Immunity: II. Interaction of the Properdin System with Polysaccharides

1955 • 268 citations

Generation of C5-Derived Lysosomal Enzyme-Releasing Activity (C5a) by Lysates of Leukocyte Lysosomes

1974 • 197 citations

The production of granulomata by antigen‐antibody complexes

1969 • 184 citations

Effects of activated complement components on enzyme secretion by macrophages.

1976 • 162 citations

The immunopathogenesis of schistosomiasis: A multidisciplinary approach

1972 • 161 citations

CHANGES IN CELLULAR ENZYME LEVELS AND EXTRACELLULAR RELEASE OF LYSOSOMAL ACID HYDROLASES IN MACROPHAGES EXPOSED TO GROUP A STREPTOCOCCAL CELL WALL SUBSTANCE

1974 • 155 citations

Mechanisms of Cell and Tissue Injury Induced by Group A Streptococci: Relation to Poststreptococcal Sequelae

1972 • 146 citations

Comparison between macrophage activation and enhancement of nonspecific resistance to tumors by mycobacterial immunoadjuvants.

1975 • 111 citations

In vitro synthesis of factor B of the alternative pathway of complement activation by mouse peritoneal macrophages

1976 • 97 citations

EXPERIMENTAL CHRONIC GLOMERULITIS

1968 • 91 citations

The binding of human lgG subclasses to human monocytes

1972 • 80 citations

Effects of dental plaque on the production and release of lysosomal hydrolases by macrophages in culture

1973 • 78 citations

In vitro synthesis of some complement components (C1q, C3 and C4) by lymphoid tissues and circulating leucocytes in man.

1975 • 72 citations

RELATION OF RHEUMATIC-LIKE CARDIAC LESIONS OF THE MOUSE TO LOCALIZATION OF GROUP A STREPTOCOCCAL CELL WALLS

1969 • 71 citations

Reactions in the Periodontium to Continuous Antigenic Stimulation in Sensitized Gnotobiotic Rats

1974 • 71 citations

The reaction of zymosan with the properdin system in normal and C4-deficienct guinea pig serum. Demonstration of C3- and C5-cleaving multi-unit enzymes, both containing factor B, and acceleration of their formation by the classical complement pathway.

1973 • 62 citations

Independent and consecutive action of the complement components C5, C6 and C7 in immune hemolysis — I

1970 • 58 citations

An investigation of the egg-white mucoproteins, ovomucoid and ovalbumin

1961 • 54 citations

Inhibition of In Vitro Growth of Lymphoma Cells by Macrophages From Tumor-Bearing Mice

1975 • 53 citations

Dextran sulphate: a synthetic activator of C3 via the alternative pathway. I. Influence of molecular size and degree of sulphation on the activation potency.

1975 • 51 citations

Nonspecific complement activation by streptococcal structures. II. Properdin-independent initiation of the alternate pathway.

1976 • 48 citations

Immune complexes in rheumatoid synovitis: a mixed staining immunofluorescence study.

1970 • 48 citations

Interactions of the Complement System with Native and Chemically Modified Endotoxins

1968 • 48 citations

ISOLATION OF THE CAUSATIVE AGENT OF FARMER'S LUNG.

1964 • 46 citations

Pulmonary responses to particulate materials capable of activating the alternative pathway of complement

1976 • 44 citations

Pathogenesis of the chronic inflammatory lesion induced by group A streptococcal cell walls.

1974 • 43 citations

Pathophysiology of rheumatoid arthritis.

1973 • 42 citations

Ability of the T cell‐replacing polyanion dextran sulfate to trigger the alternate pathway of complement activation

1973 • 40 citations

Activation of the classical and alternate pathways of complement by Corynebacterium parvum.

1975 • 39 citations

The fixation of guinea pig complement by gamma 1 and gamma 2 immunoglobulins.

1969 • 34 citations

Activation by Some T-Independent Antigens and B Cell Mitogens of the Alternative Pathway of the Complement System

1975 • 33 citations

Analysis of bypass activation of C3 by endotoxic LPS and loss of this potency.

1973 • 33 citations

INHIBITION OF GUINEA-PIG COMPLEMENT IN VITRO AND IN VIVO BY CARRAGEENIN.

1963 • 32 citations

Bypass-activation of the complement system starting with C3-II. C3-activation by gamma-1-immune aggregates in guinea pig serum

1973 • 13 citations