High Affinity Binding of Latent Matrix Metalloproteinase-9 to the α2(IV) Chain of Collagen IV

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

1996 • 1,555 citations

Isolation and Characterization of a Spontaneously Immortalized Human Breast Epithelial Cell Line, MCF-10

1990 • 1,495 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin.

1992 • 519 citations

Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts

1990 • 428 citations

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants

1997 • 427 citations

Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.

1990 • 374 citations

Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).

1995 • 324 citations

Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2

1997 • 279 citations

Binding of gelatinases A and B to type-I collagen and other matrix components

1995 • 270 citations

Extracellular Matrix Binding Properties of Recombinant Fibronectin Type II-like Modules of Human 72-kDa Gelatinase/Type IV Collagenase

1995 • 221 citations

Assessment of the role of the fibronectin-like domain of gelatinase A by analysis of a deletion mutant.

1994 • 211 citations

Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different ? chains of human type IV collagen

1995 • 207 citations

Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.

1992 • 201 citations

[28] Gelatinases A and B

1995 • 182 citations

Enhanced expression of tissue inhibitor of metalloproteinase‐2 (TIMP‐2) in the stroma of breast carcinomas correlates with tumor recurrence

1994 • 173 citations

Urokinase Plasminogen Activator and Gelatinases Are Associated with Membrane Vesicles Shed by Human HT1080 Fibrosarcoma Cells

1997 • 169 citations

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

1990 • 158 citations

Tumor promoter-stimulated Mr 92,000 gelatinase secreted by normal and malignant human cells: isolation and characterization of the enzyme from HT1080 tumor cells.

1990 • 151 citations

The complete primary structure of the alpha 2 chain of human type IV collagen and comparison with the alpha 1(IV) chain.

1988 • 149 citations

Membrane proteases: roles in tissue remodeling and tumour invasion

1992 • 139 citations

Immunohistochemical localization of matrix metallloproteinase 2 and its specific inhibitor timp‐2 in neoplastic tissues with monclonal antibodies

1994 • 137 citations

Complex Roles of Matrix Metalloproteinases in Tumor Progression

1996 • 121 citations

Phorbol ester-induced cell surface association of matrix metalloproteinase-9 in human MCF10A breast epithelial cells.

1997 • 93 citations

Evidence for the involvement of type II domains in collagen binding by 72 kDa type IV procollagenase

1991 • 72 citations

Localization of 92-kDa Type IV Collagenase in Human Skin Tumors: Comparison with Normal Human Fetal and Adult Skin

1993 • 64 citations

Enrichment of collagen and gelatin degrading activities in the plasma membranes of human cancer cells.

1987 • 60 citations

Extraction of type‐IV collagenase/gelatinase from plasma membranes of human cancer cells

1990 • 51 citations

ISolation and characterization of cerebral resistance vessel endothelium in culture

1993 • 50 citations

Identification of a specific receptor for interstitial collagenase on osteoblastic cells.

1994 • 42 citations

Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.

1989 • 39 citations

The Recognition Sites of the Integrins α1β1 and α2β1 within Collagen IV Are Protected against Gelatinase A Attack in the Native Protein

1996 • 26 citations