Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

1989 • 3,458 citations

“Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin

1953 • 3,421 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Risk Factors for Breast Cancer in Women with Proliferative Breast Disease

1985 • 1,817 citations

Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation.

1992 • 1,686 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

Langerhans'-Cell Histiocytosis (Histiocytosis X) -- A Clonal Proliferative Disease

1994 • 999 citations

Atypical hyperplastic lesions of the female breast. A long-term follow-up study

1985 • 963 citations

Breast Cancer

1992 • 695 citations

Clonal origin of human tumors

1976 • 662 citations

Immunoglobulin-Gene Rearrangements as Unique Clonal Markers in Human Lymphoid Neoplasms

1983 • 621 citations

Microsatellite instability: marker of a mutator phenotype in cancer.

1994 • 552 citations

A Prospective Study of Benign Breast Disease and the Risk of Breast Cancer

1992 • 491 citations

Microsatellite alterations as clonal markers for the detection of human cancer.

1994 • 448 citations

Instability of short tandem repeats (microsatellites) in human cancers

1994 • 413 citations

Use of Restriction Fragment Length Polymorphisms to Determine the Clonal Origin of Human Tumors

1985 • 387 citations

A comparison of the results of long-term follow-up for atypical intraductal hyperplasia and intraductal hyperplasia of the breast

1990 • 374 citations

High frequencies of short frameshifts in poly-CA/TG tandem repeats borne by bacteriophage M13 inEscherichia coliK-12

1987 • 362 citations

A PROSPECTIVE STUDY OF THE DEVELOPMENT OF BREAST CANCER IN 16,692 WOMEN WITH BENIGN BREAST DISEASE

1988 • 328 citations

Breast Cancer

1992 • 303 citations

Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia.

1995 • 289 citations

Breast Cancer

1992 • 249 citations

A study of the origin of ‘shadow bands’ seen when typing dinucleotide repeat polymorphisms by the PCR

1993 • 246 citations

Cystic disease of the breast: Relationship to carcinoma

1964 • 213 citations

Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p.

1995 • 207 citations

Microsatellite instability and loss of heterozygosity in breast cancer.

1994 • 189 citations

Five polymorphic microsatellite VNTRs on the human X chromosome.

1990 • 164 citations

Genetic evidence for an independent origin of multiple preneoplastic and neoplastic lung lesions

1995 • 160 citations

Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellite instability in lobular breast carcinomas.

1995 • 141 citations

Molecular genetic studies of early breast cancer evolution

1994 • 120 citations

p53 abnormalities and genomic instability in primary human breast carcinomas.

1995 • 108 citations

Risk of Breast Cancer after Benign Breast Diseases

1992 • 98 citations

Chromosomal aneuploidy in proliferative breast disease

1994 • 98 citations

Chromosome abnormalities in benign hyperproliferative disorders of epithelial and stromal breast tissue

1995 • 92 citations

Clonal analysis by study of X chromosome inactivation in formalin-fixed paraffin-embedded tissue.

1994 • 88 citations

Clonal analysis of predominantly intraductal carcinoma and precancerous lesions of the breast by means of polymerase chain reaction.

1994 • 65 citations

Microsatellite instabilities at five chromosomes in primary breast tumors.

1994 • 60 citations

Microsatellite instability and pathological aspects of breast cancer

1995 • 54 citations

Multiple dispersed spontaneous mutations: a novel pathway of mutation in a malignant human cell line.

1991 • 52 citations

Immunohistochemical expression of the mutant p53 protein and nuclear DNA content during the transition from benign to malignant breast disease

1994 • 52 citations

Benign breast disease: absence of genetic alterations at several loci implicated in breast cancer malignancy.

1995 • 34 citations

On the Specific Adsorption of Alcohols at the Salicylaldehyde/Water Interface

1941 • 18 citations

Spontaneous length variation in microsatellite dna from human T‐cell clones

1995 • 17 citations