Physiological roles for adenosine and ATP in synaptic transmission in the spinal dorsal horn

The pharmacological basis of therapeutics

1981 • 2,853 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Is there a basis for distinguishing two types of P2-purinoceptor?

1985 • 1,353 citations

Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones

1977 • 1,284 citations

Calcium Channels, Stores, and Oscillations

1990 • 1,208 citations

The Challenge of Pain

1996 • 1,198 citations

Hyperpolarizing Vasodilators Activate ATP-sensitive K ⁺ Channels in Arterial Smooth Muscle

1989 • 1,197 citations

Subclasses of external adenosine receptors.

1980 • 1,087 citations

Substance P: Localization in the Central Nervous System and in Some Primary Sensory Neurons

1975 • 1,029 citations

The sense of flutter-vibration: comparison of the human capacity with response patterns of mechanoreceptive afferents from the monkey hand.

1968 • 966 citations

Advances in Pain Research and Therapy

1985 • 963 citations

Activity-dependent neuronal plasticity following tissue injury and inflammation

1992 • 933 citations

Adenosine 5'-Triphosphate-Sensitive Potassium Channels

1988 • 888 citations

Cell membrane receptors for drugs and hormones: A multidisciplinary approach

1979 • 850 citations

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.

1986 • 821 citations

ATP receptor-mediated synaptic currents in the central nervous system

1992 • 814 citations

The responses of human muscle spindle endings to vibration of non‐contracting muscles.

1976 • 796 citations

Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers

1979 • 785 citations

The role of adenosine and its nucleotides in central synaptic transmission

1981 • 767 citations

A basis for distinguishing two types of purinergic receptor

1978 • 725 citations

The sensitivity of muscle spindle afferents to small sinusoidal changes of length

1969 • 708 citations

Adenosine receptors and behavioral actions of methylxanthines.

1981 • 705 citations

Adenosine receptors: targets for future drugs

1982 • 681 citations

Central Projections of Identified, Unmyelinated (C) Afferent Fibers Innervating Mammalian Skin

1986 • 670 citations

Effects of substance P on functionally identified units in cat spinal cord

1976 • 655 citations

How does adenosine inhibit transmitter release?

1988 • 649 citations

A physiological role for GABAB receptors in the central nervous system

1988 • 643 citations

The Physiological Role of Adenosine In The Central Nervous System

1985 • 628 citations

Two distinct adenosine-sensitive sites on adenylate cyclase.

1977 • 574 citations

Cutaneous Mechanoreceptors and Nociceptors

1973 • 561 citations

ATP mediates fast synaptic transmission in mammalian neurons

1992 • 549 citations

Tachykinins

1988 • 542 citations

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

1989 • 537 citations

Organization in the Spinal Cord

1981 • 514 citations

The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves

1959 • 498 citations

Physiological roles for adenosine and adenosine 5′-triphosphate in the nervous system

1981 • 484 citations

Adenosine as a Neuromodulator

1985 • 462 citations

Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels

1990 • 458 citations

Th molecular organization of adrenal chromaffin granules

1980 • 455 citations

Substance P: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons

1979 • 455 citations

The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells.

1987 • 452 citations

The relative sensitivity to vibration of muscle receptors of the cat

1967 • 448 citations

Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential

1992 • 447 citations

Neurons that subserve the sensory-discriminative aspects of pain

1977 • 429 citations

Suramin: a reversible P₂‐purinoceptor antagonist in the mouse vas deferens

1988 • 426 citations

Adenosine and the concept of ‘retaliatory metabolites’

1984 • 422 citations

Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine

1982 • 417 citations

Responses of mechanoreceptive afferent units in the glabrous skin of the human hand to sinusoidal skin displacements

1982 • 416 citations

Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes

1990 • 409 citations

Overview: Purinergic Mechanisms

1990 • 408 citations

Organization of the Spinal Cord

1964 • 402 citations

ATP excites a subpopulation of rat dorsal horn neurones

1983 • 389 citations

Further subclassification of ATP receptors based on agonist studies

1991 • 374 citations

Release of substance P from the cat spinal cord.

1987 • 371 citations

The effect of adenosine on the release of the transmitter from the phrenic nerve of the rat

1972 • 366 citations

Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin

1981 • 363 citations

Effect of substance P in cat dorsal horn neurones activated by noxious stimuli

1977 • 362 citations

ADENINE NUCLEOTIDES AND SYNAPTIC TRANSMISSION IN THE in vitro RAT HIPPOCAMPUS

1980 • 357 citations

Molecular Cloning and Characterization of a Rat A₁-Adenosine Receptor that is Widely Expressed in Brain and Spinal Cord

1991 • 341 citations

Effects of adenosine and adenine nucleotides on synaptic transmission in the cerebral cortex

1979 • 338 citations

Receptor for ATP in the membrane of mammalian sensory neurones

1983 • 335 citations

Pharmacology and electrophysiology of ATP-activated ion channels

1992 • 326 citations

The influence of naloxone on analgesia produced by peripheral conditioning stimulation

1979 • 322 citations

Suramin antagonizes responses to P₂‐purinoceptor agonists and purinergic nerve stimulation in the guinea‐pig urinary bladder and taenia coli

1990 • 317 citations

Inhibitory and excitatory factors influencing the receptive fields of lamina 5 spinal cord cells

1969 • 290 citations

Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor

1986 • 284 citations

Pharmacology and Nerve-Endings

1935 • 280 citations

RDC8 codes for an adenosine A2 receptor with physiological constitutive activity

1990 • 270 citations

An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus

1983 • 257 citations

Calcium‐dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.

1986 • 256 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Characteristics and function of Ca2+ — and inositol 1,4,5-trisphosphate-releasable stores of Ca2+ in neurons

1992 • 253 citations

Adenosine-activated potassium conductance in cultured striatal neurons.

1985 • 253 citations

P₂‐purinoceptors of two subtypes in the rabbit mesenteric artery: reactive blue 2 selectively inhibits responses mediated via the P_2y‐ but not the P_2x‐purinoceptor

1987 • 245 citations

ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics

1990 • 243 citations

The electrophysiology of adenosine in the mammalian central nervous system

1991 • 238 citations

Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes.

1990 • 237 citations

Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation.

1991 • 237 citations

Cloning and expression of an A1 adenosine receptor from rat brain.

1991 • 235 citations

The capillary dilator substances in dry powders of spinal roots; a possible role of adenosine triphosphate in chemical transmission from nerve endings

1954 • 233 citations

On the Mechanism of Action of Theophylline and Caffeine

1985 • 228 citations

Intracellular ADP activates K⁺ channels that are inhibited by ATP in an insulin‐secreting cell line

1986 • 227 citations

Micro‐iontophoretic studies on neurones in the cuneate nucleus

1967 • 227 citations

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors

1985 • 223 citations

Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides

1979 • 222 citations

Modulation of ATP-sensitive K+ channels in skeletal muscle by intracellular protons

1990 • 217 citations

On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings.

1984 • 214 citations

Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes

1990 • 213 citations

Structure and function of A ₁ adenosine receptors ¹

1991 • 212 citations

Pain alleviation by vibratory stimulation

1984 • 211 citations

Rapid release of endothelin and ATP from isolated aortic endothelial cells exposed to increased flow

1990 • 211 citations

[ ³ H]Adenosine Triphosphate: Release during Stimulation of Enteric Nerves

1971 • 204 citations

The role of purines in nociception

1989 • 198 citations

Endothelial cells cultured from human umbilical vein release ATP, substance P and acetylcholine in response to increased flow

1990 • 194 citations

The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor.

1991 • 191 citations

Adenosine agonists reduce voltage‐dependent calcium conductance of mouse sensory neurones in cell culture.

1986 • 188 citations

Monoclonal antibodies against carbohydrate differentiation antigens identify subsets of primary sensory neurones

1984 • 185 citations

Response of Pacinian corpuscles to sinusoidal vibration

1961 • 183 citations

The sense of flutter-vibration evoked by stimulation of the hairy skin of primates: Comparison of human sensory capacity with the responses of mechanoreceptive afferents innervating the hairy skin of monkeys

1969 • 183 citations

Substance P and Spinal Neurones

1975 • 183 citations

Cytochemistry of Cell Glycoconjugates

1981 • 178 citations

ATP-sensitive K+ channels regulate resting potential of pulmonary arterial smooth muscle cells

1992 • 177 citations

Modulation of ION Channels in Neurons and Other Cells

1988 • 176 citations

Drugs used in the treatment of asthma

1990 • 175 citations

Ecto-protein kinase activity on the external surface of neural cells

1986 • 173 citations

On the nature of vibration receptors in the hind limb of the cat

1961 • 172 citations

Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands.

1980 • 168 citations

Intrathecal substance P and somatostatin in rats: behaviors indicative of sensation

1983 • 167 citations

Intracellular analysis of a postsynaptic action of adenosine in the rat hippocampus

1982 • 167 citations

Immunohistochemistry of Adenosine Deaminase: Implications for Adenosine Neurotransmission

1984 • 166 citations

Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin?

1984 • 165 citations

Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS

1984 • 164 citations

The substantia gelatinosa Rolandi of the rat. Fine structure, cytochemistry (acid phosphatase) and changes after dorsal root section

1974 • 163 citations

Characterization of inhibition mediated by adenosine in the hippocampus of the rat in vitro.

1989 • 160 citations

Adenosine-containing neurons in the brain localized by immunocytochemistry

1986 • 159 citations

Classification of adenosine receptors mediating antinociception in the rat spinal cord

1986 • 152 citations

ATP‐sensitive K+ channels in rat pancreatic beta‐cells: modulation by ATP and Mg2+ ions.

1989 • 152 citations

The source of choline for acetylcholine synthesis in a sympathetic ganglion

1969 • 148 citations

post‐synaptic excitation and inhibition from primary afferents in neurones of the spinocervical tract

1968 • 147 citations

ATP-activated channels in rat and bullfrog sensory neurons: current- voltage relation and single-channel behavior

1990 • 145 citations

POTENTIATION OF ADENOSINE AND THE ADENINE NUCLEOTIDES BY DIPYRIDAMOLE

1966 • 143 citations

Substance P reduces tail-flick latency: Implications for chronic pain syndromes

1982 • 137 citations

Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts

1981 • 137 citations

On the mechanism of nucleotide diphosphate activation of the ATP‐sensitive K+ channel in ventricular cell of guinea‐pig.

1991 • 132 citations

Pain, Itch, and Vibration

1960 • 130 citations

Effects of adenosine 5′-monophosphate and adenosine 5′-triphosphate on functionally identified units in the cat spinal dorsal horn. Evidence for a differential effect of adenosine 5′-triphosphate on nociceptive vs non-nociceptive units

1985 • 128 citations

Adenosine actions on CA1 pyramidal neurones in rat hippocampal slices.

1985 • 127 citations

Autoradiographic localization of adenosine uptake sites in rat brain using [3H]nitrobenzylthioinosine

1985 • 125 citations

Adenosine A1 and A2 receptors of the substantia gelatinosa are located predominantly on intrinsic neurons: an autoradiography study.

1988 • 124 citations

DEPRESSION OF EVOKED POTENTIALS IN BRAIN SLICES BY ADENOSINE COMPOUNDS

1978 • 124 citations

G Protein Modulation of Calcium Currents in Neurons

1990 • 123 citations

Characterization and localization of adenosine receptors in rat spinal cord

1984 • 122 citations

The pharmacology of the inhibition of dorsal horn neurones by impulses in myelinated cutaneous afferents in the cat

1975 • 121 citations

FRAP: Histochemistry of the Primary Nociceptive Neuron

1981 • 121 citations

In vivo bahavioral assessment of central nervous system purinergic receptors

1981 • 120 citations

G-Proteins and Potassium Currents in Neurons

1990 • 120 citations

Distribution of adenosine deaminase activity in rat brain and spinal cord

1986 • 119 citations

The antidiabetic sulfonylurea glibenclamide is a potent blocker of the ATP-modulated K+ channel in insulin secreting cells

1987 • 117 citations

Pharmacology and Nerve Endings

1935 • 116 citations

Morphine, capsaicin and K+ release purines from capsaicin-sensitive primary afferent nerve terminals in the spinal cord.

1989 • 115 citations

Sensory transmitters regulate intracellular calcium in dorsal horn neurons

1988 • 115 citations

Characteristics of responses from receptors from the flexor longus digitorum muscle and the adjoining interosseous region of the cat

1960 • 114 citations

Sensory mechanisms of the spinal cord

1979 • 113 citations

Pre- and postsynaptic actions of adenosine in the in vitro rat hippocampus

1987 • 106 citations

Analgesia following transcutaneous electrical stimulation and its partial reversal by a narcotic antagonist

1977 • 106 citations

Identification of A1 and A2 adenosine receptors in the rat spinal cord.

1987 • 104 citations

Adenosine receptors in the nervous system

1989 • 102 citations

Spinal adenosine modulates descending antinociceptive pathways stimulated by morphine.

1986 • 102 citations

Structure-activity relationships for enhancement of adenosine A1 receptor binding by 2-amino-3-benzoylthiophenes.

1990 • 100 citations

Uptake by central nervous tissues as a mechanism for the regulation of extracellular adenosine concentrations

1984 • 97 citations

The ionic basis of adenosine receptor actions on post‐ganglionic neurones in the rat.

1983 • 94 citations

Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat

1987 • 91 citations

Autoreceptor‐mediated purinergic and cholinergic inhibition of motor nerve terminal calcium currents in the rat.

1991 • 91 citations

Vibratory stimulation for the relief of pain of dental origin

1981 • 91 citations

Effects of (−)-N6-(R-phenylisopropyl)-adenosine (PIA) and caffeine on nociception and morphine-induced analgesia, tolerance and dependence in mice

1985 • 89 citations

Responses of functionally identified neurones in the dorsal horn of the cat spinal cord to substance P, neurokinin A and physalaemin

1991 • 88 citations

Adenosine release may mediate spinal analgesia by morphine

1989 • 88 citations

Turnover of adenine nucleotides in cholinergic synaptic vesicles of the Torpedo electric organ

1978 • 87 citations

Effects of Intrathecal Injection of the Adenosine Receptor Agonists R-Phenylisopropyl-Adenosine and N-Ethylcarboxamide-Adenosine on Nociception and Motor Function in the Rat

1990 • 87 citations

Cytochemical and Physiological Properties of Sensory and Dorsal Horn Neurons That Transmit Cutaneous Sensation

1983 • 87 citations

Neurotransmitter modulation of calcium current in rat spinal cord neurons

1990 • 87 citations

Role of Spinal Adenosine Receptors in Modulating the Hyperesthesia Produced by Spinal Glycine Receptor Antagonism

1989 • 86 citations

Adenosine mediates a slow hyperpolarizing synaptic potential in autonomic neurones

1984 • 84 citations

Long-term results of vibratory stimulation as a pain relieving measure for chronic pain

1984 • 82 citations

Substance P immunoreactive neurons following neonatal administration of capsaicin

1981 • 82 citations

Comparison of the effects of substance P, neurokinin A, physalaemin and eledoisin in facilitating a nociceptive reflex in the rat

1986 • 82 citations

Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow

1986 • 81 citations

Excitation of single sensory neurones in the rat caudal trigeminal nucleus by iontophoretically applied adenosine 5′-triphosphate

1983 • 80 citations

Adenosine and ATP Receptors

2007 • 80 citations

Antinociceptive effects in mice after intrathecal injection of 5′-N-ethylcarboxamide adenosine

1984 • 78 citations

Bicuculline and spinal inhibition produced by dorsal column stimulation in the cat

1985 • 78 citations

Adenosine Triphosphatase Activity at the External Surface of Chicken Brain Synaptosomes

1983 • 77 citations

Assessment of the role of A1/A2 adenosine receptors mediating the purine antinociception, motor and autonomic function in the rat spinal cord.

1989 • 77 citations

Ecto - adenosine triphosphatase activity at the cholinergic nerve endings of the torpedo electric organ

1983 • 76 citations

ATP release from dorsal spinal cord synaptosomes: characterization and neuronal origin

1993 • 76 citations

Anatomical and cytochemical relationships of adenosine deaminase-containing primary afferent neurons in the rat

1985 • 75 citations

Naloxone does not affect pain relief induced by electrical stimulation in man

1983 • 75 citations

Adenosine receptor activation by adenine nucleotides requires conversion of the nucleotides to adenosine

1980 • 74 citations

Functional linkage between nociception and fluoride-resistant acid phosphatase activity in the Rolando substance.

1975 • 71 citations

Adenosine Triphosphate and Adenosine Triphosphatase in Hormone-Containing Granules of Posterior Pituitary Gland

1968 • 70 citations

THE SPECIFICITY OF 5'-NUCLEOTIDASE IN THE BRAIN OF THE MOUSE

1965 • 70 citations

Adenosine in Rat Cerebral Cortex: Its Determination, Normal Values, and Correlation to AMP and Cyclic AMP during Shortlasting Ischemia

1977 • 67 citations

Studies on the adenosine‐receptor mediating the augmentation of histamine‐induced inositol phospholipid hydrolysis in guinea‐pig cerebral cortex

1987 • 67 citations

Vibratory stimulation for the alleviation of chronic pain.

1983 • 67 citations

Involvement of A2 adenosine receptors in spinal mechanisms of antinociception

1987 • 66 citations

Adenosine and cyclic AMP in cerebral cortex of rats in hypoxia, status epilepticus and hypercapnia

1978 • 63 citations

Nucleoside transport in rat cerebral-cortical synaptosomes. Evidence for two types of nucleoside transporters

1988 • 62 citations

The distribution of 5′‐nucleotidase in the brain of the mouse

1967 • 62 citations

GTP and GDP activation of K+ channels that can be inhibited by ATP

1986 • 59 citations

5′-Nucleotidase in the Nervous System

1986 • 59 citations

Failure of naloxone to reverse analgesia from transcutaneous electrical stimulation in patients with chronic pain.

1981 • 57 citations

Morphine releases endogenous adenosine from the spinal cord in vivo

1987 • 57 citations

Subtypes of P₂‐Purinoceptors

1990 • 55 citations

Ectoprotein Kinase in the Regulation of Cellular Responsiveness to Extracellular ATP^a

1990 • 54 citations

Cloning and expression of a bovine adenosine A₁ receptor cDNA

1992 • 54 citations

Reconstitution of the ATP-sensitive potassium channel of skeletal muscle. Activation by a G protein-dependent process.

1989 • 53 citations

2‐Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin‐sensitive manner.

1989 • 52 citations

ATP-sensitive K+ channels from aortic smooth muscle incorporated into planar lipid bilayers

1991 • 51 citations

Adenosine-sensitive phosphoinositide turnover in a newly established renal cell line

1989 • 51 citations

Distribution of glomeruli with fluoride-resistant acid phosphatase (FRAP)-containing terminals in the substantia gelatinosa of the rat

1986 • 50 citations

Calcium-dependent inactivation of the ATP-sensitive K+ channel of rat ventricular myocytes

1988 • 50 citations

Localization of [3H]nitrobenzylthioinosine binding sites in rat spinal cord and primary afferent neurons

1985 • 49 citations

Differential responses of nociceptive vs. non-nociceptive spinal dorsal horn neurones to cutaneously applied vibration in the cat

1990 • 49 citations

Characteristics of K+- and veratridine-induced release of ATP from synaptosomes prepared from dorsal and ventral spinal cord

1985 • 48 citations

Antinociceptive effects in the rat of an adenosine analogue, N6-phenylisopropyladenosine

1983 • 47 citations

Flow-induced release of adenosine 5′-triphosphate from endothelial cells of the rat mesenteric arterial bed

1992 • 47 citations

Somatically recorded Ca-currents in guinea-pig hippocampal and olfactory cortex neurones are resistant to adenosine action

1984 • 47 citations

Modification of human pain threshold by specific tactile receptors

1979 • 47 citations

Ultrastructural localization of acid phosphatase in synaptic terminals of the rat substantia gelatinosa Rolandi

1970 • 46 citations

High‐ and low‐affinity binding sites for [³H]‐α,β‐methylene ATP in rat urinary bladder membranes

1990 • 46 citations

Molecular cloning of adenosine A1 and A2 receptors

1991 • 44 citations

Glucose-Induced Electrical Activity in β-Cells: Feedback Control of ATP-Sensitive K+ Channels by Ca2+

1990 • 44 citations

P₂‐Purinoceptor Antagonists^a

1990 • 44 citations

Sodium‐Dependent Uptake of Nucleosides by Dissociated Brain Cells from the Rat

1989 • 43 citations

The subcellular distribution of 5′-nucleotidase activity in mouse cerebellum

1977 • 43 citations

[3H]-α,β-Methylene ATP, a radioligand labelling P2-purinoceptors

1989 • 41 citations

Pharmacological Characterization of Rapidly Accumulated Adenosine by Dissociated Brain Cells from Adult Rat

1988 • 41 citations

Failure of Naloxone to Reverse Analgesia from Transcutaneous Electrical Stimulation in Patients with Chronic Pain

1981 • 41 citations

Autoradiographic studies on the uptake of adenosine and on binding of adenosine analogues in neurons and astrocytes of cultured rat cerebellum and spinal cord

1988 • 40 citations

Evaluation of adenosine agonists as potential analgesics

1989 • 40 citations

Adenosine Receptors

1992 • 40 citations

Influence of naloxone on relief of acute oro-facial pain by transcutaneous electrical nerve stimulation (TENS) or vibration

1986 • 38 citations

The actions of adenosine and various nucleosides and nucleotides on the isolated toad spinal cord

1978 • 37 citations

5'-NUCLEOTIDASE AND AN ACID PHOSPHATASE OF SPINAL CORD COMPARATIVE HISTOCHEMISTRY AND SPECIFICITY OF THE ENZYMES IN MOUSE AND CAT SPINAL CORDS. CYTOLOGIC LOCALIZATION IN MOUSE SUBSTANTIA GELATINOSA

1974 • 37 citations

DEVELOPMENT OF NICOTINIC RESPONSES IN THE RAT ADRENAL MEDULLA AND LONG‐TERM EFFECTS OF NEONATAL NICOTINE ADMINISTRATION

1977 • 36 citations

The distribution of 5′-nucleotidase in subcellular fractions of mouse cerebellum

1970 • 36 citations

Adenosine deaminase and purinergic neuroregulation

1990 • 34 citations

Effects of conditioning vibratory stimulation on pain threshold of the human tooth

1982 • 34 citations

Immunohistochemical localization of adenosine deaminase in primary afferent neurons of the rat

1984 • 33 citations

Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord

1992 • 33 citations

Physiological characteristics of responses of wide dynamic range spinal neurones to cutaneously applied vibration in the cat

1990 • 32 citations

Antinociception produced by interactions between intrathecally administered adenosine agonists and norepinephrine

1990 • 31 citations

Spinal antinociceptive effects of adenosine compounds in mice

1987 • 30 citations

The pathway for the slow inhibitory postsynaptic potential in bullfrog sympathetic ganglia

1986 • 30 citations

Regional distribution of acid phosphatase-positive axonal systems in the rat spinal cord and medulla, representing central terminals of cutaneous and visceral nociceptive neurons

1977 • 29 citations

Vasodepressor mechanisms of 2-(1-octynyl)-adenosine (YT-146), a selective adenosine A2 receptor agonist, involve the opening of glibenclamide-sensitive K+ channels

1992 • 29 citations

Presynaptic depression of synaptic response of Renshaw cells by adenosine 5′-monophosphate

1977 • 27 citations

Failure of naloxone to reverse peripheral transcutaneous electro-analgesia in patients suffering from acute trauma.

1978 • 27 citations

Cholinergic Synaptic Vesicles

1988 • 27 citations

Functional activity of the adenosine binding enhancer, PD 81,723, in the in vitro hippocampal slice

1991 • 25 citations

Characteristics of neuronal release of ATP

1984 • 25 citations

Active transport of nucleosides and nucleoside drugs

1989 • 24 citations

Adenosine derived from hydrolysis of presynaptically released ATP inhibits neuromuscular transmission in the rat

1991 • 22 citations

Tachykinins enhance the depression of spinal nociceptive neurons caused by cutaneously applied vibration in the cat

1988 • 21 citations

Permeation of purine derivatives into the cerebrospinal fluid of dogs

1968 • 19 citations

ATP Compartmentation in Neuroendocrine Secretory Vesicles

1990 • 19 citations

Vibrotactile thresholds in mechanoreceptive afferents innervating the foot pad of the cat: The importance of stimulus frequency and duration

1984 • 19 citations

Purine-induced depression of dorsal horn neurons in the cat spinal cord: Enhancement by tachykinins

1987 • 19 citations

Morphine (intracerebroventricular) activates spinal systems to inhibit behavior induced by putative pain neurotransmitters.

1989 • 18 citations

Differentiating Adenosine Receptors and Adenosine Uptake Sites in Brain

1984 • 17 citations

Adenosine analogs do not inhibit the potassium-stimulated release of substance P from rat spinal cord slices

1990 • 17 citations

ATP‐Sensitive K⁺ channels mediate an IPSP in dorsal horn neurones elicited by sensory stimulation

1992 • 15 citations

8-Phenyltheophylline reverses the antinociceptive action of morphine in the periaqueductal gray

1991 • 15 citations

5'-NUCLEOTIDASE AND ACID PHOSPHATASE OF SPINAL CORD QUANTITATIVE HISTOCHEMISTRY IN CAT AND MOUSE SPINAL CORDS AND IN MOUSE BRAIN

1974 • 14 citations

Adenosine and related compounds do not affect nerve terminal excitability in rat CNS

1980 • 13 citations

An open label trial of the possible analgesic effects of dipyridamole

1989 • 13 citations

Glucose-induced electrical activity in beta-cells. Feedback control of ATP-sensitive K+ channels by Ca2+? [corrected]

1990 • 13 citations

Cellular biology of ectoenzymes

1987 • 12 citations

GABA pretreatment enhances glutamate mediated phosphoinositide hydrolysis in neurons

1988 • 10 citations

LIMINAL AND SUPRALIMINAL RESPONSE CHARACTERISTICS OF MECHANORECEPTORS OF THE HAIRY AND FOOT PAD SKIN OF CAT DETERMINED WITH SHORT TACTILE PULSES

1983 • 10 citations