Cooperative Assembly of RNA Polymerase II Transcription Complexes

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

The Enhanceosome and Transcriptional Synergy

1998 • 545 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

DNA topology and a minimal set of basal factors for transcription by RNA polymerase II

1993 • 374 citations

Recycling of the general transcription factors during RNA polymerase II transcription.

1995 • 309 citations

Mechanism of action of a yeast activator: Direct effect of GAL4 derivatives on mammalian TFIID-promoter interactions

1988 • 286 citations

Association of an activator with an RNA polymerase II holoenzyme.

1995 • 237 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

Polymerase II Promoter Activation: Closed Complex Formation and ATP-Driven Start Site Opening

1992 • 220 citations

A mechanism for TAFs in transcriptional activation: activation domain enhancement of TFIID-TFIIA--promoter DNA complex formation.

1994 • 207 citations

A general mechanism for transcriptional synergy by eukaryotic activators

1995 • 185 citations

Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination

1995 • 164 citations

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

1993 • 161 citations

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA.

1992 • 160 citations

A Potent GAL4 Derivative Activates Transcription at a Distance in Vitro

1990 • 148 citations

The Switch between Latency and Replication of Epstein-Barr Virus

1990 • 143 citations

The requirement for the basal transcription factor IIE is determined by the helical stability of promoter DNA.

1995 • 143 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

1996 • 136 citations

Architectural Transcription Factors: Proteins That-Remodel DNA

1997 • 129 citations

Combinatorial regulation of transcription II: the immunoglobulin μ heavy chain gene

1995 • 116 citations

Transcription initiation by RNA polymerase II does not require hydrolysis of the beta-gamma phosphoanhydride bond of ATP.

1994 • 99 citations

Transcriptional synergy by the Epstein-Barr virus transactivator ZEBRA

1992 • 92 citations

The ZEBRA activation domain: modular organization and mechanism of action.

1993 • 62 citations

A heteroduplex template circumvents the energetic requirement for ATP during activated transcription by RNA polymerase II

1994 • 61 citations

Promoter Escape by RNA Polymerase II A ROLE FOR AN ATP COFACTOR IN SUPPRESSION OF ARREST BY POLYMERASE AT PROMOTER-PROXIMAL SITES

1996 • 60 citations

A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation

1995 • 56 citations

Uncoupling of Initiation and Reinitiation Rates During HeLa RNA Polymerase II Transcription In Vitro

1993 • 45 citations

Promoter Escape by RNA Polymerase II

1997 • 38 citations

Compensatory Energetic Relationships between Upstream Activators and the RNA Polymerase II General Transcription Machinery

1998 • 31 citations

Uncoupling of initiation and reinitiation rates during HeLa RNA polymerase II transcription in vitro.

1993 • 23 citations

Biochemical mechanism of transcriptional activation by GAL4-VP16

1996 • 21 citations

How Eukaryotic Transcription Activators Increase Assembly of Preinitiation Complexes

1993 • 8 citations