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Reactive Oxygen Species Regulate a Slingshot-Cofilin Activation Pathway

Data up to Jan 2025

Published2009
Citations175
References57

Total Citations Per Year

Abstract

References (57)

The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

2007 • 6,348 citations

Cell Migration: Integrating Signals from Front to Back

2003 • 4,755 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Production of large amounts of hydrogen peroxide by human tumor cells.

1991 • 2,465 citations

Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system

2006 • 1,813 citations

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1998 • 1,384 citations

ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

2008 • 1,324 citations

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

1998 • 1,263 citations

Arp2/3 Complex and Actin Depolymerizing Factor/Cofilin in Dendritic Organization and Treadmilling of Actin Filament Array in Lamellipodia

1999 • 1,150 citations

Regulation of the actin cytoskeleton in cancer cell migration and invasion

2006 • 1,071 citations

Vascular NAD(P)H oxidases: specific features, expression, and regulation

2003 • 1,029 citations

Proteins of the ADF/Cofilin Family: Essential Regulators of Actin Dynamics

1999 • 1,004 citations

Novel gp91 phox Homologues in Vascular Smooth Muscle Cells

2001 • 841 citations

Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

2002 • 740 citations

The signaling mechanism of ROS in tumor progression

2006 • 730 citations

Redox Redux: Revisiting PTPs and the Control of Cell Signaling

2005 • 696 citations

Control of Actin Reorganization by Slingshot, a Family of Phosphatases that Dephosphorylate ADF/Cofilin

2002 • 670 citations

Regulation of Actin Filament Network Formation Through ARP2/3 Complex: Activation by a Diverse Array of Proteins

2001 • 667 citations

Regulation of Nox and Duox enzymatic activity and expression

2007 • 490 citations

The cofilin pathway in breast cancer invasion and metastasis

2007 • 469 citations

Life at the Leading Edge: The Formation of Cell Protrusions

1993 • 442 citations

Angiotensin receptors: a new role in cancer?

2005 • 422 citations

NADPH oxidases: not just for leukocytes anymore!

2003 • 387 citations

NADPH oxidases and angiotensin II receptor signaling

2008 • 374 citations

Neurodegenerative stimuli induce persistent ADF/cofilin–actin rods that disrupt distal neurite function

2000 • 374 citations

Compartmentalization of Redox Signaling Through NADPH Oxidase–Derived ROS

2008 • 348 citations

Cofilin phosphatases and regulation of actin dynamics

2005 • 325 citations

Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics

2004 • 321 citations

Epidermal Growth Factor Receptor Transactivation by Angiotensin II Requires Reactive Oxygen Species in Vascular Smooth Muscle Cells

2001 • 285 citations

Interplay between components of a novel LIM kinase–slingshot phosphatase complex regulates cofilin

2005 • 284 citations

Calcium Signal-induced Cofilin Dephosphorylation Is Mediated by Slingshot via Calcineurin

2005 • 228 citations

Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation

2009 • 226 citations

Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration

2005 • 209 citations

A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia

2004 • 195 citations

Redox Changes of Cultured Endothelial Cells and Actin Dynamics

2000 • 167 citations

Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration

2004 • 162 citations

The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes

2000 • 161 citations

Regulation of Signal Transduction Through Protein Cysteine Oxidation

2006 • 160 citations

Nox1 is over‐expressed in human colon cancers and correlates with activating mutations in K‐Ras

2008 • 153 citations

Nox1 Mediates Basic Fibroblast Growth Factor-Induced Migration of Vascular Smooth Muscle Cells

2007 • 143 citations

The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

2004 • 133 citations

Transforming growth factor-β1 regulates macrophage migration via RhoA

2006 • 131 citations

IQGAP1 Regulates Reactive Oxygen Species–Dependent Endothelial Cell Migration Through Interacting With Nox2

2005 • 122 citations

Reactive oxygen species regulate F‐actin dynamics in neuronal growth cones and neurite outgrowth

2008 • 119 citations

Probing cellular protein targets of H2O2 with fluorescein‐conjugated iodoacetamide and antibodies to fluorescein

1998 • 98 citations

Regulation of Nox1 Activity via Protein Kinase A-mediated Phosphorylation of NoxA1 and 14-3-3 Binding

2007 • 98 citations

Nox1-dependent superoxide production controls colon adenocarcinoma cell migration

2007 • 98 citations

The Slingshot Family of Phosphatases Mediates Rac1 Regulation of Cofilin Phosphorylation, Laminin-332 Organization, and Motility Behavior of Keratinocytes

2007 • 89 citations

Chronophin Mediates an ATP-Sensing Mechanism for Cofilin Dephosphorylation and Neuronal Cofilin-Actin Rod Formation

2008 • 87 citations

Vascular Endothelial Growth Factor Causes Translocation of p47 to Membrane Ruffles through WAVE1

2003 • 83 citations

Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation

1997 • 76 citations

Mechanism of Angiotensin II-induced Superoxide Production in Cells Reconstituted with Angiotensin Type 1 Receptor and the Components of NADPH Oxidase

2007 • 76 citations

Effect of reactive oxygen intermediates on the in vitro invasive capacity of tumor cells and liver metastasis in mice

1993 • 75 citations

Dual Regulation of Cofilin Activity by LIM Kinase and Slingshot-1L Phosphatase Controls Platelet-Derived Growth Factor–Induced Migration of Human Aortic Smooth Muscle Cells

2007 • 62 citations

Proteomic profiling and identification of cofilin responding to oxidative stress in vascular smooth muscle

2006 • 58 citations

Quantification and morphologic demonstration of reactive oxygen species produced by Walker 256 tumor cells in vitro and during metastasis in vivo.

1994 • 36 citations

RETRACTED: Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer’s disease and cerebral amyloid angiopathy

2007 • 19 citations

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