Diabetes Results from a Late Change in the Autoimmune Response of NOD Mice

Type I Diabetes Mellitus

1986 • 1,615 citations

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

1995 • 1,528 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

1965 • 1,338 citations

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

The Pathogenesis of Insulin-Dependent Diabetes Mellitus

1994 • 1,077 citations

Amino Acid Homology Between the Encephalitogenic Site of Myelin Basic Protein and Virus: Mechanism for Autoimmunity

1985 • 941 citations

Insulin-Dependent Diabetes Mellitus as an Autoimmune Disease

1994 • 818 citations

Deciding who gets what.

1983 • 561 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

EVIDENCE FOR A LONG PREDIABETIC PERIOD IN TYPE I (INSULIN-DEPENDENT) DIABETES MELLITUS

1981 • 480 citations

The histopathology of the pancreas in Type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1986 • 453 citations

Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes

1990 • 356 citations

RUBELLA INFECTION AND DIABETES MELLITUS

1978 • 355 citations

Checkpoints in the progression of autoimmune disease: lessons from diabetes models.

1996 • 340 citations

Prevention of autoimmune insulitis by expression of I–E molecules in NOD mice

1987 • 308 citations

A Prospective Study of the Development of Diabetes in Relatives of Patients with Insulin-Dependent Diabetes

1990 • 288 citations

First-Degree Relatives of Patients with Type I Diabetes Mellitus

1985 • 226 citations

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

1990 • 204 citations

Prevention of Type I Diabetes in Nonobese Diabetic Mice by Virus Infection

1988 • 202 citations

Competitive Insulin Autoantibody Assay: Prospective Evaluation of Subjects at High Risk for Development of Type I Diabetes Mellitus

1987 • 181 citations

Pre-Type I Diabetes: Linear Loss of Beta Cell Response to Intravenous Glucose

1984 • 171 citations

Altered Cytokine Activity in Adjuvant Inhibition of Autoimmune Diabetes

1993 • 151 citations

The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice.

1991 • 147 citations

Persistent MHV (mouse hepatitis virus) infection reduces the incidence of diabetes mellitus in non-obese diabetic mice

1991 • 147 citations

Are Insulin Autoantibodies Markers for Insulin-Dependent Diabetes Mellitus?

1986 • 146 citations

Successful Allotransplantation of Mouse Pancreatic Islets to Nonimmunosuppressed Recipients

1980 • 124 citations

Examination of islets in the pancreas biopsy specimens from newly diagnosed Type 1 (insulin-dependent) diabetic patients

1990 • 105 citations

Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence.

1990 • 89 citations

Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection

1992 • 87 citations

Non-obese-diabetic mice: immune mechanisms of pancreatic ?-cell destruction

1984 • 76 citations

AN AUTOPSY STUDY OF THE ISLETS OF LANGERHANS IN ACUTE-ONSET JUVENILE DIABETES MELLITUS

1977 • 73 citations

Islet-Infiltrating Lymphocytes from Prediabetic NOD Mice Rapidly Transfer Diabetes to NOD-scid/scid mice

1995 • 68 citations

Expression of the Co-stimulator Molecule B7–1 in Pancreatic β-Cells Accelerates Diabetes in the NOD Mouse

1995 • 67 citations

Paradoxical lessening of autoimmune processes in non‐obese diabetic mice afterinfection with the diabetogenic variant of encephalomyocarditis virus

1990 • 55 citations

Circulating lymphocyte populations and autoantibodies in non-obese diabetic (NOD) mice: a longitudinal study.

1987 • 55 citations

Radioassay Determination of Insulin Autoantibodies in NOD Mice: Correlation With Increased Risk of Progression to Overt Diabetes

1989 • 52 citations

Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse

1994 • 34 citations

Immunological aspect of non-obese diabetic mice: immune islet cell-killing mechanism and cell-mediated immunity

1984 • 28 citations

Protection of nonobese diabetic mice from autoimmune diabetes by reduction of islet mass before insulitis.

1996 • 26 citations

Type I diabetes mellitus: A predictable autoimmune disease with interindividual variation in the rate of β cell destruction

1989 • 24 citations

Course of pancreatic beta cell destruction in prediabetic NOD mice: a histomorphometric evaluation.

1994 • 19 citations

The histocompatibility requirements of ovarian grafts in mice

1960 • 16 citations

Insulin autoantibodies in non-obese diabetic (NOD) mice and streptozotocin-induced diabetic mice.

1988 • 16 citations

Regulation of autoimmune diabetes: Characteristics of non‐islet‐antigen specific therapies

1996 • 13 citations

Autoimmune diabetes: Caught in the causality trap?

1995 • 12 citations