Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

1988 • 811 citations

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

1993 • 811 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Stress proteins in biology and medicine

1990 • 731 citations

Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity.

1992 • 702 citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 • 698 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data

1984 • 610 citations

fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen.

1988 • 518 citations

Stress proteins in biology and medicine

1990 • 502 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene

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Definitive evidence for hypoxic cells influencing cure in cancer therapy.

1978 • 422 citations

Role of Oxygen in Modifying the Radiosensitivity of E. Coli B.

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Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

1992 • 353 citations

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.

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The hypoxic tumor cell: A target for selective cancer chemotherapy

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MAMMALIAN GENES INDUCED BY RADIATION; Activation of Genes Associated with Growth Control

1992 • 284 citations

Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells.

1983 • 282 citations

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding.

1993 • 270 citations

Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in the FSaIIC murine fibrosarcoma.

1990 • 222 citations

Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin

1991 • 213 citations

Polyamines Differentially Modulate the Transcription of Growth-associated Genes in Human Colon Carcinoma Cells

1989 • 211 citations

Identification of Newly Transcribed <scp>RNA</scp>

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Response to adversity: molecular control of gene activation following genotoxic stress.

1991 • 189 citations

Activation of the heat shock transcription factor by hypoxia in mammalian cells.

1990 • 173 citations

In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response.

1993 • 128 citations

Chemical modifiers of cancer treatment.

1988 • 127 citations

Imaging tumor hypoxia and tumor perfusion.

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Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes

1991 • 120 citations

Escape from redox regulation enhances the transforming activity of Fos.

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Response of Chinese hamster ovary cells to anticancer drugs under aerobic and hypoxic conditions

1981 • 110 citations

Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance

1991 • 108 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecanoylphorbol 13-acetate.

1993 • 100 citations

Inducible cellular responses to ultraviolet light irradiation and other mediators of DNA damage in mammalian cells

1990 • 88 citations

Identification of Residues in the Human DNA Repair Enzyme HAP1 (Ref-1) That are Essential for Redox Regulation of Jun DNA Binding

1993 • 84 citations

A simplification of the nuclear run-off transcription assay.

1989 • 75 citations

Mammalian Genes Coordinately Regulated by Growth Arrest Signals and DNA-Damaging Agents

1989 • 64 citations

Sensitizers and protectors in radiotherapy

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Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells.

1992 • 51 citations

Effects of hypoxia on detoxicating enzyme activity and expression in HT29 colon adenocarcinoma cells.

1994 • 50 citations

Mammalian Genes Induced by Radiation: Activation of Genes Associated with Growth Control

1992 • 16 citations

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

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Chemotherapy of Cancer

1978 • 6 citations