[¹²⁵I]‐GR231118: a high affinity radioligand to investigate neuropeptide Y Y₁ and Y₄ receptors

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1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

A receptor subtype involved in neuropeptide-Y-induced food intake

1996 • 892 citations

XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.

1998 • 867 citations

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1986 • 632 citations

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1986 • 570 citations

Neuropeptide Y: emerging evidence for a functional role in seizure modulation

1999 • 470 citations

Regional distribution of Y‐receptor subtype mRNAs in rat brain

1999 • 400 citations

Neuropeptide Y-Related Peptides and their Receptors--Are the Receptors Potential Therapeutic Drug Targets?

1993 • 380 citations

Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues

1992 • 379 citations

Cloning and Functional Expression of a Human Y4 Subtype Receptor for Pancreatic Polypeptide, Neuropeptide Y, and Peptide YY

1995 • 372 citations

The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226

1994 • 369 citations

Cloning of a Human Receptor of the NPY Receptor Family with High Affinity for Pancreatic Polypeptide and Peptide YY

1995 • 321 citations

Cloning and Expression of a Novel Neuropeptide Y Receptor

1996 • 280 citations

Effects of neuropeptide Y on the electrical properties of neurons

1994 • 261 citations

Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents

1998 • 254 citations

Identification of a Novel Hypothalamic Neuropeptide Y Receptor Associated with Feeding Behavior

1996 • 237 citations

Neuropeptide Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinizing hormone.

1992 • 233 citations

Comparative characterization and autoradiographic distribution of neuropeptide Y receptor subtypes in the rat brain

1993 • 203 citations

Neuropeptide Y feeding receptors: are multiple subtypes involved?

1999 • 200 citations

Species differences in the expression and distribution of the neuropeptide Y Y1, Y2, Y4, and Y5 receptors in rodents, guinea pig, and primates brains

1998 • 186 citations

Potent neuropeptide Y Y1 receptor antagonist, 1229U91: blockade of neuropeptide Y-induced and physiological food intake.

1996 • 185 citations

Multiple Receptors for the Pancreatic Polypeptide (PP-Fold) Family: Physiological Implications

1998 • 180 citations

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1996 • 175 citations

Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system—I. Radioimmunoassay and chromatographic characterisation

1986 • 157 citations

Autoradiographic distribution of [125I]Leu31,Pro34]PYY and [125I]PYY3-36 binding sites in the rat brain evaluated with two newly developed Y1 and Y2 receptor radioligands

1996 • 157 citations

Inactivation of a Novel Neuropeptide Y/Peptide YY Receptor Gene in Primate Species

1996 • 151 citations

Expression cloning of a human brain neuropeptide Y Y2 receptor

1996 • 142 citations

Expression and Characterization of the Neuropeptide Y Y₅Receptor Subtype in the Rat Brain

1998 • 142 citations

Characterization of saturable binding sites for circulating pancreatic polypeptide in rat brain

1990 • 139 citations

Regional Distribution of Putative NPY Y₁Receptors and Neurons Expressing Y₁mRNA in Forebrain Areas of the Rat Central Nervous System

1993 • 139 citations

High-affinity neuropeptide Y receptor antagonists.

1995 • 138 citations

Time-varying magnetic fields increase cytosolic free Ca2+ in HL-60 cells

1990 • 138 citations

Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system

1997 • 137 citations

Characterization of neuropeptide Y binding sites in rat brain membrane preparations using [125I][Leu31,Pro34]peptide YY and [125I]peptide YY3-36 as selective Y1 and Y2 radioligands.

1995 • 122 citations

GR231118 (1229U91) and other analogues of the C-terminus of neuropeptide Y are potent neuropeptide Y Y1 receptor antagonists and neuropeptide Y Y4 receptor agonists

1998 • 113 citations

Differential distribution of neuropeptide Y1 and Y2 receptors in the rat brain

1990 • 112 citations

The cloned rat pancreatic polypeptide receptor exhibits profound differences to the orthologous receptor.

1996 • 110 citations

Neuropeptide Y receptor binding sites in rat brain: differential autoradiographic localizations with 125I-peptide YY and 125I- neuropeptide Y imply receptor heterogeneity

1989 • 107 citations

Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family

1996 • 102 citations

Distribution of a novel hypothalamic neuropeptide Y receptor gene and its absence in rat

1998 • 85 citations

Characterization of the peptide binding requirements for the cloned human pancreatic polypeptide-preferring receptor.

1996 • 82 citations

Receptor-selective analogs demonstrate NPY/PYY receptor heterogeneity in rat brain

1991 • 81 citations

Quantitative receptor autoradiography demonstrates a differential distribution of neuropeptide-Y Y1 and Y2 receptor subtypes in human and rat brain

1993 • 77 citations

Distribution of pancreatic polypeptide receptors in the rat brain

1997 • 75 citations

[Leu31-Pro34] neuropeptide Y identifies a subtype of 125I-labeled peptide YY binding sites in the rat brain

1992 • 68 citations

The neuropeptide Y (Y4) receptor is highly expressed in neurones of the rat dorsal vagal complex

1997 • 67 citations

Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIBO3304 (Y1) and CGP71683A (Y5)

2000 • 67 citations

The Neuropeptide Y Y1 Antagonist, 1229U91, A Potent Agonist for the Human Pancreatic Polypeptide-Preferring (NPY Y4) Receptor

1998 • 66 citations

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1997 • 63 citations

Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors

1995 • 61 citations

Localization of Neuropeptide Y Y1 mRNA in the Human Brain: Abundant Expression in Cerebral Cortex and Striatum

1997 • 58 citations

Quantitative autoradiographic localization of [125I] neuropeptide Y receptor binding sites in rat spinal cord and the effects of neonatal capsaicin, dorsal rhizotomy and peripheral axotomy

1992 • 57 citations

Quantitative autoradiographic distribution of [125i]bolton-hunter neuropeptide y receptor binding sites in rat brain. comparison with [125i]peptide yy receptor sites

1990 • 56 citations

Differential distribution of neuropeptide Y Y1 and Y2 receptors in rat and guinea-pig brains

1996 • 54 citations

Structural study of the N-terminal segment of neuropeptide tyrosine

1990 • 53 citations

Synthesis of receptor antagonists of neuropeptide Y.

1992 • 52 citations

Comparative autoradiographic distribution of neuropeptide Y Y-1 receptors visualized with the Y1 receptor agonist [125l][Leu31, Pro34]PYY and the non-peptide antagonist [3H]BIBP3226

1996 • 46 citations

Characterization of the neuropeptide Y5 receptor in the human hypothalamus: a lack of correlation between Y5 mRNA levels and binding sites

1998 • 45 citations

Characterization of neuropeptide Y receptor subtypes in the normal human brain, including the hypothalamus

1997 • 43 citations

Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain

1998 • 42 citations

Expression of the neuropeptide Y Y1 receptor mRNA in the human brain

1996 • 42 citations

Neuropeptide Y Receptors: Autoradiographic Distribution in the Brain and Structure‐Activity Relationshipsa

1990 • 40 citations

Comparative developmental profile of the neuropeptide Y Y1 receptor gene and protein in the rat brain

1997 • 40 citations

Labeling of neuropeptide Y receptors in SK-N-MC cells using the novel, nonpeptide Y1 receptor-selective antagonist [3H]BIBP3226

1995 • 37 citations

Distribution of neuropeptide Y receptor expression in the rat suprachiasmatic nucleus

1998 • 36 citations

Discrete distribution of the neuropeptide Y Y5 receptor gene in the human brain: an in situ hybridization study

1998 • 35 citations

High levels of specific neuropeptide Y/pancreatic polypeptide receptors in the rat hypothalamus and brainstem

1996 • 34 citations

A Structure-Activity Analysis of the Cloned Rat and Human Y4 Receptors for Pancreatic Polypeptide

1997 • 33 citations

The neuropeptide Y Y1 receptor selective radioligand, [125I][Leu31,Pro34]peptide YY, is also a high affinity radioligand for human pancreatic polypeptide 1 receptors

1996 • 27 citations

Neuropeptide Y: a novel neuroendocrine peptide in the control of pituitary hormone secretion, and its relation to luteinizing hormone.

1992 • 25 citations

Comparison of Y-receptor subtype expression in the rat hippocampus

1998 • 23 citations

Neuropeptide y receptor types in the mammalian brain

1997 • 23 citations

GW1229, a novel neuropeptide Y Y1 receptor antagonist, inhibits the vasoconstrictor effect of neuropeptide Y in the hamster microcirculation

1997 • 19 citations

Identification of multiple neuropeptide Y receptor subtypes in the human frontal cortex

1997 • 15 citations

Expression of the neuropeptide Y Y1 receptor in human embryonic kidney 293 cells: ligand binding characteristics, in situ hybridization and receptor autoradiography

1995 • 13 citations

Potent and selective tools to investigate neuropeptide Y receptors in the central and peripheral nervous systems: BIBO3304 (Y1) and CGP71683A (Y5)

2000 • 6 citations