The GABAB Receptor Agonist Baclofen Attenuates Cocaine- and Heroin-Seeking Behavior by Rats

The neural basis of drug craving: An incentive-sensitization theory of addiction

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Limbic Activation During Cue-Induced Cocaine Craving

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Acute Effects of Cocaine on Human Brain Activity and Emotion

1997 • 1,263 citations

Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers

1986 • 1,134 citations

Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants.

1984 • 1,060 citations

Activation of memory circuits during cue-elicited cocaine craving.

1996 • 939 citations

The neuropsychological basis of addictive behaviour

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Conditioning factors in drug abuse: can they explain compulsion?

1998 • 680 citations

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist

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Conditioned responses to cocaine-related stimuli in cocaine abuse patients

1992 • 457 citations

Dissociation in Conditioned Dopamine Release in the Nucleus Accumbens Core and Shell in Response to Cocaine Cues and during Cocaine-Seeking Behavior in Rats

2000 • 446 citations

Enhanced behavioural control by conditioned reinforcers following microinjections of d-amphetamine into the nucleus accumbens

1984 • 440 citations

Control of cocaine-seeking behavior by drug-associated stimuli in rats: Effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens

2000 • 412 citations

Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach behavior.

2001 • 319 citations

Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour

2000 • 309 citations

Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.

1996 • 301 citations

Differential Involvement of NMDA, AMPA/Kainate, and Dopamine Receptors in the Nucleus Accumbens Core in the Acquisition and Performance of Pavlovian Approach Behavior

2001 • 300 citations

Dissociable Effects of Antagonism of NMDA and AMPA/KA Receptors in the Nucleus Accumbens Core and Shell on Cocaine-seeking Behavior

2001 • 287 citations

Acquisition, maintenance and reinstatement of intravenous cocaine self-administration under a second-order schedule of reinforcement in rats: effects of conditioned cues and continuous access to cocaine

1998 • 249 citations

Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement

1996 • 225 citations

Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behavior

2001 • 218 citations

Dissociation of Primary and Secondary Reward-Relevant Limbic Nuclei in an Animal Model of Relapse

2000 • 213 citations

Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey.

1973 • 213 citations

Dissociable Effects of Lidocaine Inactivation of the Rostral and Caudal Basolateral Amygdala on the Maintenance and Reinstatement of Cocaine-Seeking Behavior in Rats

2002 • 198 citations

Baclofen Attenuates the Reinforcing Effects of Cocaine in Rats

1996 • 196 citations

CONDITIONED REINFORCEMENT IN SECOND‐ORDER SCHEDULES¹

1966 • 187 citations

Bromocriptine self-administration and bromocriptine-reinstatement of cocaine-trained and heroin-trained lever pressing in rats

1990 • 179 citations

Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release.

1999 • 172 citations

Differential Contributions of the Basolateral and Central Amygdala in the Acquisition and Expression of Conditioned Relapse to Cocaine-Seeking Behavior

2001 • 157 citations

Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens

1991 • 156 citations

Effects of baclofen on maintenance and reinstatement of intravenous cocaine self-administration in rats

1999 • 155 citations

Baclofen suppression of cocaine self-administration: demonstration using a discrete trials procedure

1997 • 150 citations

Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules

2000 • 149 citations

The GABAB agonist baclofen modifies cocaine self-administration in rats.

1998 • 139 citations

A comparison of the effects of intra-accumbens injections of amphetamine and morphine on reinstatement of heroin intravenous self-administration behavior

1988 • 114 citations

Stimuli associated with drug injections as events that control behavior.

1975 • 110 citations

Conditioned changes in dopamine oxidation currents in the nucleus accumbens of rats by stimuli paired with self‐administration or yoked‐administration of d‐amphetamine

1998 • 101 citations

Increased mesolimbic GABA concentration blocks heroin self-administration in the rat.

2000 • 95 citations

Intra-VTA Baclofen Attenuates Cocaine Self-Administration on a Progressive Ratio Schedule of Reinforcement

2000 • 90 citations

Activation of ventral tegmental GABAB receptors inhibits morphine-induced place preference in rats

1996 • 90 citations

The GABAB agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure

1999 • 88 citations

Second-Order Schedules of Drug Injection

1987 • 88 citations

Symmetrical effects of amphetamine and alpha-flupenthixol on conditioned punishment and conditioned reinforcement: contrasts with midazolam

1997 • 71 citations

Involvement of the Nucleus Accumbens and Medial Prefrontal Cortex in the Expression of Conditioned Hyperactivity to a Cocaine-Associated Environment in Rats

2000 • 60 citations

The relation between dopamine oxidation currents in the nucleus accumbens and conditioned increases in motor activity in rats following repeated administration of d‐amphetamine or cocaine

1998 • 55 citations

GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine

2001 • 53 citations

Heroin self-administration under a second-order schedule of reinforcement: acquisition and maintenance of heroin-seeking behaviour in rats

2000 • 45 citations

Imagery of craving in opiate addicts undergoing detoxification

1997 • 31 citations

The GABA B antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat

2002 • 31 citations